A5053492340- Glaucoma and retinal disorders
- Corneal surgery and disorders
- Retinal and Optic Conditions
- Retinal Diseases and Treatments
- Intraocular Surgery and Lenses
- Ophthalmology and Eye Disorders
- Retinal Imaging and Analysis
- Ocular Surface and Contact Lens
- Ocular Diseases and Behçet’s Syndrome
- Retinal and Macular Surgery
- Vasculitis and related conditions
- Corneal Surgery and Treatments
- Retinal Development and Disorders
- Biomedical Research and Pathophysiology
- Otitis Media and Relapsing Polychondritis
- Traumatic Ocular and Foreign Body Injuries
- Ocular Infections and Treatments
- Pituitary Gland Disorders and Treatments
- Systemic Lupus Erythematosus Research
- Advanced Differential Geometry Research
- Vascular Malformations Diagnosis and Treatment
- Thyroid Disorders and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Neonatal Health and Biochemistry
- COVID-19 and healthcare impacts
University of Pisa
2016-2025
Azienda Ospedaliera Universitaria Pisana
2015-2025
Creative Commons
2022
Misericordia University
2021
University of Pavia
2021
Istituti di Ricovero e Cura a Carattere Scientifico
2021
Ospedale Cisanello
2019
Background: Treatment for Graves' hyperthyroidism (GH) in patients with orbitopathy (GO) remains a topic of debate. This study aimed to investigate the outcome GO following glucocorticoids, depending on chosen thyroid treatment. Methods: retrospective cohort included 49 consecutive GH and moderate-to-severe, active GO, as defined by European Group Orbitopathy guidelines. Twenty-four were treated radioactive iodine (RAI) 25 methimazole (MMI). All administered intravenous methylprednisolone....
The recent outbreak of coronavirus disease 2019 (COVID-19) has been declared a public health emergency worldwide. scientific community put in much effort and published studies that described COVID-19’s biology, transmission, clinical diagnosis, candidate therapeutics, vaccines. However, to date, only few data are available on the impact COVID-19 pandemic ophthalmological care different systems, its future consequences terms disability, access sight-saving cures for many patients. To reduce...
Background Though several procedures of IOL implantation have been described (sutured scleral fixation, intra-scleral angle-supported anterior chamber, and chamber or retropupillary iris-claw IOLs), there are no randomized trials which comparing different techniques. Hence, the surgical treatment aphakia still remains controversial challenging. The purpose this study was to compare long-term efficacy rate complications versus posterior Iris-claw intraocular lenses (IOL) correct for without...
To evaluate frequency, conversion rate, and risk factors for blindness in glaucoma patients treated European Universities.This multicenter retrospective study included 2402 consecutive with at least one eye. Medical charts were inspected divided into those blind the remainder ('controls'). Blindness was defined as visual acuity≤0.05 and/or field loss to less than 10°.Unilateral bilateral respectively 11.0% 1.6% beginning, 15.5% 3.6% end of observation period (7.5±5.5 years, range:1-25...
To compare the number of eye surgical procedures performed in Italy 2 months following beginning lockdown (study period) because COVID-19 epidemic with those two earlier same year (intra-year control) and period 2019 corresponding to (inter-year control).Retrospective analysis carried out at 39 Academic hospitals. A distinction was made between elective urgent procedures. Intravitreal injections were also considered. Percentages for all incidence rate ratios (IRR) rhegmatogenous retinal...
Abstract Objectives A beneficial effect of sirolimus in Graves’ orbitopathy (GO) was reported, suggesting a possible use clinical practice. We conducted an observational, single-centre, no-profit, study to investigate the efficacy as second-line treatment for moderate-to-severe, active GO compared with methylprednisolone. Methods Data from consecutive patients given (2 mg orally on first day, followed by 0.5 mg/day 12 weeks) or methylprednisolone [500 iv/weekly (6 weeks), 250 mg/weekly...
Keratoplasty is one of the irreplaceable treatment options for corneal diseases. Currently, there no evidence to substantiate that harvested grafts from COVID-19 patients can contain SARS-CoV-2 virus and lead a systemic infection. Although risk transmission through stromal tissue low, it potentially exists. Lack clinical data, unclear potential donor-derived infection non-established recommendations transplantation during pandemic have resulted in dramatic reduction number keratoplasty...
This study assessed the 24 h circadian rhythm of intraocular pressure (IOP) using a contact lens sensor in three groups patients with open-angle glaucoma. was monocentric, cross-sectional, nonrandomized, prospective, pilot study. Eighty-nine were enrolled: 29 previously underwent an Ex-PRESS mini glaucoma device procedure (Group 1), 28 Hydrus microstent implantation 2), and 32 currently being treated medically for primary 3). Circadian patterns considered five indicators: fluctuation ranges,...
Although the expression of microRNAs (miRNAs) in retinal pigment epithelial (RPE) cells undergoing epithelial-mesenchymal transition (EMT) is involved pathogenesis proliferative vitreoretinopathy (PVR), its vitreous patients with primary detachment (RD) and different PVR grading has not yet been investigated. We assessed miRNAs humor (VH) diagnosed RD PVR.The VH was extracted from core chamber who had undergone standard vitrectomy for RD. RNA TaqMan Low-Density Arrays (TLDAs) were used miRNA...
Since the end of 2019, an outbreak severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), originating in Chinese city Wuhan has spread rapidly worldwide causing thousands deaths. Coronavirus disease (COVID-19) is supported by SARS-CoV-2 and represents causative agent a potentially fatal that great global public health concern. Italy been first European country recording elevated number infected forcing Italian Government to call for total lockdown. The lockdown had aim limit infection...
Sirolimus was found to be associated with a better outcome of Graves' orbitopathy (GO) at 24 weeks compared methylprednisolone. We conducted retrospective study investigate its efficacy and safety over longer period.