A5060427599- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Corneal surgery and disorders
- Retinal Imaging and Analysis
- Ocular Surface and Contact Lens
- Retinal and Optic Conditions
- Neurological Disorders and Treatments
- Ophthalmology and Eye Disorders
- Ophthalmology and Visual Impairment Studies
- Corneal Surgery and Treatments
- Intraocular Surgery and Lenses
- Optical Coherence Tomography Applications
- Ubiquitin and proteasome pathways
- Retinal Development and Disorders
- Retinal and Macular Surgery
- Cerebral Venous Sinus Thrombosis
- Retinopathy of Prematurity Studies
- Ocular Infections and Treatments
- Drug-Induced Ocular Toxicity
- Flavonoids in Medical Research
- Neurological Disease Mechanisms and Treatments
- Acute Ischemic Stroke Management
- Diabetes and associated disorders
- Advancements in Transdermal Drug Delivery
- Cerebrovascular and genetic disorders
Istituti di Ricovero e Cura a Carattere Scientifico
2016-2025
Fondazione G.B. Bietti
2016-2025
Thea (France)
2024
International Flame Research Foundation
2021
City, University of London
2021
Universidad de Londres
2021
Nova Scotia Health Authority
2021
Dalhousie University
2021
University of Milan
2021
Hôpital d'Instruction des Armées Bégin
2021
Glaucoma is a progressive optic neuropathy and leading cause of irreversible blindness. The disease has conventionally been characterized by an elevated intraocular pressure (IOP); however, recent research built the consensus that glaucoma not only dependent on IOP but rather represents multifactorial neuropathy. Although many risk factors have identified ranging from demographics to co-morbidities ocular structural predispositions, currently modifiable factor, most often treated topical...
PROLOGUE:
Abstract Background/Objectives To evaluate the efficacy and safety of preservative-free latanoprost eye drop emulsion in reducing intraocular pressure (IOP) versus preserved open-angle glaucoma (OAG) or ocular hypertension (OHT). Methods A Phase III non-inferiority study randomised patients with OAG/OHT 1:1 to receive latanoprost. The primary endpoint was change from baseline peak (9:00 A.M. ± 1 h) trough (4:00 P.M. IOP at Week 12 (non-inferiority margin: 95% confidence interval for...
Abstract Purpose To establish expert consensus on guidelines for implementing glaucoma virtual clinics in Italy, focusing patient suitability, essential clinical assessments and staffing requirements. Methods A modified Delphi method was used to achieve among selected Italian specialists. The steering group developed a structured questionnaire with 66 items across key areas: Patient Categories, Clinical Assessments, Roles Staffing Guidelines clinic implementation. panel of experts reviewed...
To evaluate frequency, conversion rate, and risk factors for blindness in glaucoma patients treated European Universities.This multicenter retrospective study included 2402 consecutive with at least one eye. Medical charts were inspected divided into those blind the remainder ('controls'). Blindness was defined as visual acuity≤0.05 and/or field loss to less than 10°.Unilateral bilateral respectively 11.0% 1.6% beginning, 15.5% 3.6% end of observation period (7.5±5.5 years, range:1-25...
To investigate the serum levels of Brain Derived Neurotrophic Factor (BDNF) and Nerve Growth (NGF) in patients affected by primary open angle glaucoma with a wide spectrum disease severity compared to healthy controls explore their relationship morphological functional parameters.45 at different stages 15 age-matched control subjects underwent visual field testing, peripapillary retinal nerve fibre layer thickness measurement using Spectral Domain Optical Coherence Tomography blood...
To investigate the efficacy and safety of a cross-linked gel stent (XEN45) with or without cataract surgery in treatment glaucoma patients.Five university hospitals.Prospective multicenter clinical trial.Patients inadequately controlled by poor compliance intolerance to topical therapy were included. Patients divided into those who had an implant only (Solo Group; phakic pseudophakic patients) combined (Combo Group). Differences mean intraocular pressure (IOP) number medications between...
Précis: The relationship between structural and hemodynamic parameters in patients with primary open angle glaucoma is strongest the temporal region of optic nerve. Purpose: To investigate radial peripapillary capillary (RPC) vessel density (VD) retinal nerve fiber layer (RNFL) thickness quadrants sectors head (ONH) without (POAG). Methods: In a cross-sectional prospective analysis, 191 subjects (80 early-stage POAG; 111 non-glaucomatous controls) were assessed for RNFL RPC VD each quadrant...
To compare the corneal biomechanical properties in eyes of patients with diabetes mellitus and those subjects without mellitus.Hospital eye clinic.Comparative case series.Corneal hysteresis (CH) response factor (CRF) were measured diabetic nondiabetic using Ocular Response Analyzer. Central thickness (CCT) intraocular pressure (IOP) also measured. Differences determined a 1-way analysis variance. Interassociations between ocular parameters evaluated.Sixty-one 61 123 evaluated. The CRF was...
Primary open angle glaucoma (POAG) is a progressive optic neuropathy characterized by impaired aqueous outflow and extensive remodeling in the trabecular meshwork (TM). The aim of this study was to characterize compare expression patterns selected proteins belonging tissue remodeling, inflammation growth factor pathways ex vivo glaucomatous post-mortem TMs using protein-array analysis. TM specimens were collected from 63 white subjects, including 40 patients with 23 controls. Forty POAG at...