About
Contact & Profiles
A5067750904
Research Areas
- CAR-T cell therapy research
- Immunotherapy and Immune Responses
- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Cancer Immunotherapy and Biomarkers
University of Lisbon
2024
Erasmus MC Cancer Institute
2022
Relapsed or refractory acute myeloid leukemia (AML) remains a major therapeutic challenge. We have recently developed Vδ1+ γδ T cell-based product for adoptive immunotherapy, named Delta One (DOT) cells, and demonstrated their cytolytic capacity to eliminate AML cell lines primary blasts in vitro vivo. However, the molecular mechanisms responsible broad DOT-cell recognition of cells remain poorly understood. Here, we dissected role natural killer (NK) receptor ligands by DOT cells. Screening...
10.1182/blood.2023022992
article
EN
cc-by-nc-nd
Blood
2024-03-04
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