A5041372503- Cerebrovascular and Carotid Artery Diseases
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Atherosclerosis and Cardiovascular Diseases
- Long-Term Effects of COVID-19
- Cardiac Imaging and Diagnostics
- Acute Ischemic Stroke Management
- Intensive Care Unit Cognitive Disorders
- Cardiovascular Health and Disease Prevention
- Medical Imaging Techniques and Applications
- Frailty in Older Adults
- Cardiovascular Disease and Adiposity
- Neurological Disease Mechanisms and Treatments
- Cell Adhesion Molecules Research
- Heparin-Induced Thrombocytopenia and Thrombosis
- Cardiac Arrhythmias and Treatments
- SARS-CoV-2 detection and testing
- Atrial Fibrillation Management and Outcomes
- Pneumonia and Respiratory Infections
- Respiratory Support and Mechanisms
- Anesthesia and Neurotoxicity Research
- Venous Thromboembolism Diagnosis and Management
- Extracellular vesicles in disease
University of Cambridge
2023-2025
Cambridge University Hospitals NHS Foundation Trust
2024
University of Birmingham
2023
University College Dublin
2023
Addenbrooke's Hospital
2023
Abstract Purpose Delirium is a neuropsychiatric disorder delineated by an acute change in cognition, attention, and consciousness. It common, particularly older adults, but poorly recognised. Frailty the accumulation of deficits conferring increased risk adverse outcomes. We set out to determine how severity frailty, as measured using CFS, affected delirium rates, recognition hospitalised people United Kingdom. Methods Adults over 65 years were included observational multi-centre audit...
Background Microcalcification and macrocalcification are critical processes in atherosclerotic plaque progression, though how these relate to the risk of stroke recurrence symptomatic carotid atherosclerosis is poorly understood. Methods We performed a post-hoc analysis data from ICARUSS study, where individuals with acute ischemic originating ipsilateral stenosis ≥50% underwent 18F-sodium fluoride-positron emission tomography (NaF-PET) measure microcalcification. Tracer uptake was...
Introduction: Atrial fibrillation (AF) detected after stroke (AFDAS) may represent a distinct clinical entity to that of known AF (KAF). However, there is limited long-term outcome data available for patients with AFDAS. More information regarding prognosis in AFDAS required inform future trial design these patients. Patients and methods: We used (2015–2019) from national prospective registry consecutive acute ischaemic AF. was defined as new diagnosis on electrocardiograph or cardiac...
Atherosclerosis is a chronic systemic inflammatory condition of the vasculature and leading cause stroke. Luminal stenosis severity an important factor in determining vascular risk. Conventional imaging modalities, such as angiography or duplex ultrasonography, are used to quantify inform clinical care but provide limited information on plaque biology. Inflammatory processes central atherosclerotic progression destabilization. 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)...
Abstract Introduction 18 F-sodium fluoride (NaF) positron-emission tomography (PET) is increasingly being used to measure microcalcification in atherosclerotic disease vivo . Correlations have been drawn between sodium uptake and the presence of high-risk plaque features, as well its association with clinical sequelae. The aim this review was perform a meta-analysis NaF on PET imaging relation symptomatic asymptomatic disease. Methods A systematic performed according PRISMA guidelines, via...