A5087266647- Curcumin's Biomedical Applications
- Advanced Drug Delivery Systems
- Advancements in Transdermal Drug Delivery
- Drug Solubulity and Delivery Systems
- Natural Antidiabetic Agents Studies
- Nanoparticles: synthesis and applications
- Moringa oleifera research and applications
- Malaria Research and Control
- Ethnobotanical and Medicinal Plants Studies
- Lipid Membrane Structure and Behavior
- Surfactants and Colloidal Systems
- Morinda citrifolia extract uses
- Inflammatory Bowel Disease
- Hemoglobinopathies and Related Disorders
- Essential Oils and Antimicrobial Activity
- Natural Compound Pharmacology Studies
- Synthesis and Characterization of Heterocyclic Compounds
- Food Science and Nutritional Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Pomegranate: compositions and health benefits
- Hibiscus Plant Research Studies
- Insect Pest Control Strategies
- Complement system in diseases
- Pharmacological Effects of Medicinal Plants
- Nephrotoxicity and Medicinal Plants
University of Kinshasa
2014-2024
Université Catholique du Graben
2023
Université de Kisangani
2022
Université Officielle de Bukavu
2021-2022
UCLouvain
2012-2016
In the present study, silver nanoparticles (AgNPs) were synthesized using aqueous leaf extracts of three Congolese plant species, namely Brillantaisia patula (BR-PA), Crossopteryx febrifuga (CR-FE) and Senna siamea (SE-SI). The obtained AgNPs studied for their optical, structural, surface morphological antibacterial properties. prepared characterized by UV-Visible spectra, Transmission Electron Microscopy (TEM), Fourier Transform Infrared Spectroscopy (FTIR), X-ray spectroscopy (EDX)...
Antimicrobial natural polymer film with silver nanoparticles (AgNPs) biosynthesized using aqueous plant root extracts as reducing capping agents and for formatting show extensive applicability pathogenic microorganism problems. The formation of AgNPs was confirmed by transmission electron microscopy (TEM) scanning microscopy–energy-dispersive spectroscopy (SEM–EDS) techniques. antimicrobial activity biofilm green analysed inhibiting the growth Gram-negative Gram-positive bacteria culture...
Silver nanoparticles (AgNPs) biosynthesized using aqueous medical plant extracts as reducing and capping agents show multiple applicability for bacterial problems. The aim of this study was to expand the boundaries on AgNPs a novel, low-toxicity, cost-effective alternative green approach biosynthesis metallic NPs Calendula officinalis (Calendula) Hyssopus (Hyssopus) extracts. formation confirmed by transmission electron microscopy (TEM), scanning (SEM), energy-dispersive spectroscopy (EDS)...
Background Supra-nutritional doses of curcumin, derived from the spice Curcuma longa, have been proposed as a potential treatment inflammation and metabolic disorders related to obesity. The aim present study was test whether longa extract rich in curcumin associated with white pepper (Curcuma-P®), at compatible human use, could modulate systemic diet-induced obese mice. We questioned relevance changes adiposity gut microbiota effect Curcuma-P® Methodology/Principal Findings Mice were fed...
Low aqueous solubility and poor oral bioavailability are limiting factors in the delivery of voxelotor, an antisickling agent. To overcome these limitations, a voxelotor self-nanoemulsifying drug system was developed. Various oils, surfactants, cosurfactants were screened for their solubilization potential drug. The area nanoemulsification identified using ternary phase diagram. An experimental mixture design desirability function applied to select SNEDDSs that contain maximum amount lipids...
The aim of this study was to evaluate the antimalarial efficacy and acute toxicity 80% ethanol extracts Enantia olivacea, Garcinia punctata Massularia acuminata stem barks. in vivo these investigated alone or combination by 4-day suppressive test. To assess toxicity, mice were treated with a single oral dose each individual (2,000 mg/kg) combined extract (≤ 1,200 mg/kg). During 7 days, animals observed for any clinical signs changes body weight mortality. At 200 mg/kg, resulted,...
Context: Garcinia kola seeds are widely used in Congolese traditional medicine to treat uncomplicated malaria. While the ethanolic extract of these (GK) is reputed for oral antimalarial activity, some its constituents have shown poor water solubility, which might compromise further phytopharmaceutical developments. Aims: To develop a self-nanoemulsifying drug delivery system (SNEDDS) GK, since SNEDDS promising vehicles enhancing product solubility. Methods: GK was loaded into liquid...