A5017965976- Antibiotic Resistance in Bacteria
- Bacterial biofilms and quorum sensing
- Urinary Tract Infections Management
- Microbial Metabolism and Applications
- Antimicrobial Resistance in Staphylococcus
- Antibiotic Use and Resistance
- Nanoparticles: synthesis and applications
- Orthopedic Infections and Treatments
- Bacterial Identification and Susceptibility Testing
- Surgical site infection prevention
- Streptococcal Infections and Treatments
- Insect and Pesticide Research
- Enterobacteriaceae and Cronobacter Research
- Tryptophan and brain disorders
- Nephrotoxicity and Medicinal Plants
- Insect Pest Control Strategies
- Diabetic Foot Ulcer Assessment and Management
- Infective Endocarditis Diagnosis and Management
- Biochemical and Structural Characterization
- Antimicrobial Peptides and Activities
- Mosquito-borne diseases and control
- Botulinum Toxin and Related Neurological Disorders
- Reproductive tract infections research
- Pharmaceutical Quality and Counterfeiting
- Wound Healing and Treatments
University of Kinshasa
2014-2023
Kinshasa General Hospital
2023
In the present study, silver nanoparticles (AgNPs) were synthesized using aqueous leaf extracts of three Congolese plant species, namely Brillantaisia patula (BR-PA), Crossopteryx febrifuga (CR-FE) and Senna siamea (SE-SI). The obtained AgNPs studied for their optical, structural, surface morphological antibacterial properties. prepared characterized by UV-Visible spectra, Transmission Electron Microscopy (TEM), Fourier Transform Infrared Spectroscopy (FTIR), X-ray spectroscopy (EDX)...
Surgical site infections (SSIs) after surgery are usually caused by Staphylococcus aureus and coagulase-negative staphylococci (CNS). In low income countries, methicillin resistant (MRSA) (MR-CNS) surgical particularly associated with high treatment cost remain a source of mortality morbidity. This study aimed to determine the prevalence sensitivity antibiotics MRSA MR-CNS isolated from SSIs.Wound swabs were collected 130 hospitalized patients in two major hospitals Kinshasa. S. CNS strains...
Background: The AWaRe tool was set up by the World Health Organization (WHO) to promote rational use of antimicrobials. Indeed, this classifies antibiotics into four groups: access, watch, reserve and not-recommended antibiotics. In Democratic Republic Congo, data on antibiotic dispensing (prescribing) health professionals according classification are scarce. research work, we aimed explore pattern from WHO strengthen national antimicrobial resistance plan. Methods: For purpose, a survey...
People infected by Human Immunodeficiency Virus (HIV) are susceptible to develop severe bacterial infections. We set out determine the frequency and sensitivity antibiotics of enterobaceriaceae isolated from urine feces HIV-infected persons.Urine samples were collected patients Centre de Traitement Ambulatoire Kabinda (CTA/Kabinda, Kinshasa) analyzed at Reference National Laboratory for HIV/AIDS Sexually Transmitted Infections. The enterobacteriaceae strains identified conventional...
S. aureus is a Gram positive bacterium which responsible for wide range of infections. This pathogen has also the ability to adhere biotic or abiotic surface such as central venous catheter (CVC) and produce biofilm. The aim this study was evaluate effect hexadecyltrimethyl ammonium bromide (HTAB) Hexadecylbetainate chloride (HBC) on Staphylococcus adherence tubing bacteria growth.Broth microdilution method used determine Minimal Inhibitory Concentration (MIC). detection slime production...
Context and objective. Bacteremia is a major cause of morbidity mortality in hospitalized patients. However, data on bacteremia sub-Saharan African countries are scarce. The aim the study was to identify etiological agents isolated patients admitted several hospitals Kisangani, Democratic Republic Congo. Methods. This series suspected cases severe infections five Kisangani (Cliniques Universitaires de Village pédiatrique, Hôpitaux généraux références Kabongo, Lubunga et Makiso) between 2017...
Group B Streptococcus (GBS) is a Gram-positive bacterium which often colonizes maternal vaginal and rectal epitheliums can be transmitted to the neonate during delivery. GBS infections may cause significant neonatal morbidity, including sepsis, pneumonia meningitis. In Democratic Republic of Congo, few studies have been done on colonization pregnant women. This study was conducted in Kinshasa, Congo order determine prevalence among women at gestational age 35 - 37 weeks antibiotic...
Foot infections resulting from biofilm producers and multi-drug resistant organisms is one of the most important complications diabetes mellitus, as it can impede wound healing process. This study was carried out in order to determine antibiotic resistance pattern production diabetic foot ulcers isolates. Clinical samples were collected patients suffering by using sterile swabs. Antibiotic susceptibility test done disk diffusion method on Mueller Hinton Agar. Biofilm formation assessed...
Abstract Background : Enterobacteriaceae are one of the most predominant pathogen in surgical site infections. In recent years we oberved increase resistance among bacteria from The aim this study was to evaluate antimicrobial suceptibility pattern isolates infections, biofilm formation and production OXA-48 carbapenemase. Methods A total 41 (19 Escherchia coli , 8 Enterobacter sp., 9 Citrobacter 5 Serratia sp. ) clinical were collected patients with SSI Hôpital Saint Joseph (Kinshasa) for...
The aim of this study was to determine the etiologic agents and antibiotic susceptibility pattern Staphylococcus aureus isolated among antiretroviral therapy users with asymptomatic urinary tract infections. Urine samples were collected for diagnostic purpose. Uropathogen bacteria identified using microbiological conventional methods, test carried out disk diffusion method. predominant microorganisms Escherichia coli (49.6 %) followed by coagulase negative staphylococci (18.4 (14.1%). All...
Background: The occurrence of urinary tract infection (UTI) caused by multi-drug resistant bacteria is increasing worldwide and has become a major public health concern that requires global attention. To promote better treatment outcome UTI raise awareness antibiotic resistance in the Democratic Republic Congo (DRC), we investigated antimicrobial profile bacterial pathogens frequently isolated from urine samples inpatients outpatients with symptoms at Monkole Hospital Center (MHC), Kinshasa...
Mosquitoes transmit serious human diseases, causing millions of deaths worldwide every year and the development resistance to chemical insecticides resulting in rebounding vectorial capacity. In this study, larvicidal bioassays for activities aqueous solutions weak acid [(NH4)2SO4 NaH2PO4] base (Na2CO3 NaHCO3) inorganic salts against late instar larvae disease vectors Anopheles stephensi Culex quinquefasciatus were carried out under laboratory settings. The four showed varied levels after 24...
Background: Gram-negative and Gram-positive microorganisms are responsible for both community hospital acquired infections. The increase, emergence, spread of antimicrobial resistance among bacteria the most important health problems worldwide. One mechanisms used by is biofilm formation. aim this study was to investigate antibiotic pattern formation ability Staphylococcus aureus Enterobacteriaceae isolates.
Investigation reports or data on the profiles of microorganisms causing infections, as well their respective antibiotic resistance patterns are lacking in health care institutions present Kisangani Region. In this purpose, retrospective study was carried out, order to determine frequency relevant pathogens and commonly used antibiotics Laboratoire de Santé Publique (Public Health Laboratory) Kisangani. Settings Design: Retrospective for a period 5 years, from January 2013 December 2017,...