- Electric and Hybrid Vehicle Technologies
- Hydraulic and Pneumatic Systems
- Real-time simulation and control systems
- Vehicle Dynamics and Control Systems
- Immune Response and Inflammation
- Fault Detection and Control Systems
- Neonatal Respiratory Health Research
- Digital Transformation in Industry
- Innovative Approaches in Technology and Social Development
- University-Industry-Government Innovation Models
- Soil Mechanics and Vehicle Dynamics
- MicroRNA in disease regulation
- Advanced Combustion Engine Technologies
Universität Bayern
2021
Linköping University
2013-2019
Center for Inherited Blood Disorders
2010
Concise regulation of the Toll signaling pathway is mandatory in neonatal innate immunity. The microRNA-146 family (miR-146a/b) was recently reported to be a regulator Toll-like receptor 4 (TLR4) through negative feedback loop mechanism. Acting as potent regulator, miRNA helps protect organism from developing overwhelming proinflammatory immune responses leading septic shock or chronic inflammatory diseases.We investigated for first time whether miRNA-146a/b plays regulatory role human...
Hybridisation of hydraulic drivetrains offers the potential efficiency improvement for on – and off-road applications. To realise advantages, a carefully designed system corresponding control strategy are required, which commonly obtained through sequential design process. Addressing component selection parameterisation simultaneously simulation-based optimisation allows exploration large space as well relations trade-offs, their evaluation in dynamic conditions exist real driving scenarios....
Simulation-based optimization is a useful tool in the design of complex engineering products. Simulation models are used to capture numerous aspects problem for objective function. Optimization results obtained can be assessed from various perspectives. In this study, component and control series hydraulic hybrid vehicle as an application, different robustness performance evaluated. Owing relatively high computational loads, efficient algorithms important provide sufficient quality at...
Hydraulic hybrids continue to receive attention as a possible solution in the search for improved fuel economy different vehicle types.This paper presents development of framework hybrid hydraulic vehicles, using Hopsan simulation tool Linköping University's Division Fluid and Mechatronic Systems (Flumes).This is then used on series transmission which employs pump control based accumulator's state-of-charge (SoC).Several simplifications were made, especially concerning mechanical...
Hybridization of hydraulic drivetrains offers the potential efficiency improvement for on- and off-road applications. To realize advantages, a carefully designed system corresponding control strategy are required, which commonly obtained through sequential design process.Addressing component selection parameterization simultaneously simulation-based optimization allows exploration large space as well relations trade-offs, their evaluation in dynamic conditions exist real driving scenarios....
Amongst the hybrid vehicle propulsion solutions aiming to improve fuel efficiency, electric currently receive most attention, especially on market. However, hydraulic hybrids are an interesting alternative, for heavier vehicles due higher power density which is beneficial if masses moved. As a step towards comprehensive design framework compare several possible architectures specified application and usage profile, model of series was previously introduced initially studied concerning...
Hybridization of a vehicle’s drivetrain can in principle help to improve its energy efficiency by allowing for recuperation kinetic and modulating the engine’s load. How well this be realized depends on appropriate sizing control additional components. The system is typically designed sequentially, with hardware setup preceding development tuning advanced controller architectures. Taking an alternative approach, component addressed simultaneously through simulation-based optimization....