ABSTRACT Due to the growing concern about diabetes worldwide, we investigated antidiabetic potential of Lactobacillus plantarum DMR14, assessing its effects on diabetic mice and identifying safe, bioactive compounds targeting DPP4 protein for drug development through various methods, including in vivo assays, GC–MS analysis molecular docking simulations. The animal experiments showed that after 3 weeks treatment, blood sugar levels given bacteria were reduced by 35.03% compared baseline....

Chiral unsymmetrical dimeric liquid crystals consisting of a cholesterol moiety as chiral entity and substituted salicylidene imine core (with the substituent being butyl or fluoro chloro group) interconnected through an even methylene spacer have been synthesised their mesomorphic properties are characterised. All dimers exhibit enantiotropic mesophases. The homologue exhibited N* phase only, fluoro- chloro-substituted compound frustrated blue phases (BPs), SmC* twisted grain boundary (TGB)...

Banking sector is one of the fastest growing sectors in Bangladesh.Modern banking becoming more complex than before.Evaluating Bangladeshi challenging task.There are so many factors, which need to be taken care while differentiating good banks from bad ones.Sound financial health a bank guarantee not only its depositors but equally significant for shareholders, employees and whole economy country as well.As result this statement, efforts have been made time time, measure position each manage...

The synthesis and characterization of stable achiral unsymmetrical four-ring banana-shaped molecules consisting a laterally chloro substituted 3,4′-disubstituted biphenyl unit with an ester linkage between the phenyl rings as central in 4-(N-4′-n-tetradecyloxysalicylidene)aminophenyl [2-chloro-5-(N-4′-n-tetradecyloxysalicylidene) aminobenzoate] 4-(N-4′-n-alkyloxysalicylidene)aminophenyl [4-chloro-5-(N-4′-n-alkyloxysalicylidene) are presented. These compounds thermally hydrolytically due to...

Achiral unsymmetrical 2-methyl 3-amino-benzoic acid (2,6-substituted toluene)-derived four-ring bent-core liquid crystals with a polar fluoro or chloro substituent at one end and an alkyloxy group (butyl to dodecyl) the other have been synthesised by simple straightforward synthetic method. The molecular structure characterisation is consistent elemental spectroscopic analysis data. materials' thermal behaviour phase investigated differential scanning calorimetry polarising optical...

Here we report the influence of terminal -F, -Cl and -NO2 substitution on elastic, dielectric polar switching behavior four-ring bent-core liquid crystals (LCs). Elastic constants nematic are key parameters in determining threshold voltage sensitivity to electro-optical response a device. The elastic properties crystal systems show atypical temperature dependence there is no hard-core theory explain behavior. However based molecular simulation atomistic calculations it found earlier studies...

Herein, we report a new type of azobenzene-based unsymmetrical bent-core molecules exhibiting photoswitchability in the liquid crystalline state, solid and solution state mixture upon UV irradiation intense visible light. The compounds exhibited solid-state photochromism exposure to light, whereas reversible phase transitions were observed via both light exposure. Crystal structure analysis reveals basic structural understanding such as nonplanar bent molecular shape, antiparallel...

We report here the synthesis and thermotropic properties of novel short-core hockey stick-shaped liquid crystalline molecules based on 1,3,4-thiadiazole core. Polar switching behavior is observed in cybotactic nematic smectic mesophases for bent-core thiadiazole derivatives. The presence lateral methoxy moiety outer phenyl ring four-ring facilitates formation spontaneous ordering phase via X-ray diffraction measurements. Anomalous temperature dependence polarization cooling explained by...

Non-symmetrical cholesterol-based dimers have emerged as crucial materials in the field of liquid crystal research, owing to their remarkable ability stabilize various exotic mesophases, including blue phases (BPIII, BPII, BPI), cholesteric nematic (N*) phase, smectic phase (SmBP), twist grain boundary (TGB) A/smectic A* (SmA/SmA*) and C/smectic C* (SmC/SmC*) phase. These mesophases garnered considerable attention due diverse applications spatial light modulation, chiro-optical devices,...

Three-ring based BLCs exhibiting orthogonal smectic and nematic phases with antiparallel arrangement as derived from SCXRD X-ray scattering results.

Hockey-stick-shaped liquid crystals are interesting due to their unusual physical properties. Nematic phase observed in these materials have shown promising ferroelectric-like switching, ease of alignment a planar and homeotropic cell, large flexoelectricity, etc. Polar moieties viz. F, Cl, NO2, etc., molecular architecture lead the development permanent dipole moment which turn affects structure Herein, we designed synthesised new series four-ring-based hockey-stick-shaped molecules having...

We report the synthesis and characterization of a new class achiral three-ring bent-core compounds with an amide ester linkage at molecular bend, which are shown to exhibit nematic/phases in wide temperature ranges around room (RT) undulated SmC phases below RT. In contrast previous studies, reported this Communication show true RT nematic phase fluid physical appearance. They strong photoluminescence mesophase found display one-dimensional array intermolecular hydrogen bonding. Furthermore,...

In this work, hydrogen-bonded liquid crystal exhibiting phase dependent fluorescence has been reported. The H-bonded materials were prepared using pyridenyl benzothiazole and alkoxy benzoic acid as H-bond acceptor donor respectively. formation of the target was confirmed via different spectroscopic technique their mesogenic behaviour studied through polarising optical microscope, differential scanning calorimetry 2D-X-ray diffraction. material showed aggregation switching when subjected to...

An extensive study on the effect of terminal halogens structure–property relationship polar L-shaped mesogens has been elucidated.

Research on low-temperature polar bent-core nematogens having lower molecular weight has gathered appreciable momentum by virtue of their significance in potential applications. However, the lack availability and easy-to-perform synthesis processes appears to be bottleneck towards fabrication thereby limiting possible device Hence, we have designed a new class achiral symmetrical three-ring-based-bent shaped molecules incorporating an imine ester linkage at bend with highly nitro/cyano...

We have investigated two new series of unsymmetrical four-ring bent-core molecules with methylated azobenzene wings exhibiting nematic mesophase. The difference between the was in relative position methyl (−CH3) substituent respect to azo (−N═N−) linkage molecule. Single-crystal X-ray diffraction analysis unravels significant insights into spatial molecular arrangement and stacking interactions these systems. materials were able show photoswitching behavior photomasking effect...

Probing “cybotactic clusters” in bent-core nematic liquid crystals using microrheological technique.

Non-symmetrically substituted four-ring achiral bent-core compounds with polar substituents, i.e.., chloro in the bent or transverse direction central core and cyano lateral at one terminal end of molecule, are designed synthesized. These molecules possess an alkoxy chain attached only molecule. The molecular structure characterization is consistent data from elemental spectroscopic analysis. materials thermal behaviour phase have been investigated by differential scanning calorimetry...

A simple molecular design of unsymmetrical bent-core molecules exhibiting low layer shrinkage and a dip in the birefringence at SmA–SmC phase transition, typical characteristics “de Vries” liquid crystals.

A new family of four-ring achiral bent-core compounds derived from 2-methyl 3-amino benzoic acid with the methyl group in bent direction incorporated into central core have been designed and synthesised. These possess an alkoxy chain attached at only one end molecule, while other arm consists a biphenyl moiety possessing highly polar cyano-group. The molecular structure has confirmed by elemental analysis spectroscopic data, thermal behaviour phase characterisation investigated differential...

First examples of smart bent-core materials that exhibited frustrated structures with high polar order and thermochromism.