Diego Garcia Castillo

ORCID: 0000-0003-3212-5417
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About
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Research Areas
  • Mollusks and Parasites Studies
  • Marine Bivalve and Aquaculture Studies
  • Marine Biology and Ecology Research
  • Genomics and Phylogenetic Studies
  • Chromosomal and Genetic Variations
  • Plant Disease Resistance and Genetics
  • Wheat and Barley Genetics and Pathology
  • Genetic diversity and population structure
  • Evolution and Genetic Dynamics
  • Lung Cancer Treatments and Mutations
  • Geological and Geochemical Analysis
  • Geological and Geophysical Studies Worldwide
  • Lung Cancer Diagnosis and Treatment
  • Radiomics and Machine Learning in Medical Imaging
  • Paleontology and Stratigraphy of Fossils
  • Gene expression and cancer classification
  • Marine and coastal plant biology
  • Bioinformatics and Genomic Networks

University of Concepción
2025

Institute of Science and Technology Austria
2023-2024

Chinese Academy of Agricultural Sciences
2020-2021

Institute of Crop Sciences
2020-2021

Universidad Nacional de La Plata
2014

Key innovations are fundamental to biological diversification, but their genetic basis is poorly understood. A recent transition from egg-laying live-bearing in marine snails ( Littorina spp.) provides the opportunity study architecture of an innovation that has evolved repeatedly across animals. Individuals do not cluster by reproductive mode a genome-wide phylogeny, local genealogical analysis revealed numerous small genomic regions where all live-bearers carry same core haplotype....

10.1126/science.adi2982 article EN Science 2024-01-04

Predicting the outcomes of adaptation is a major goal evolutionary biology. When temporal changes in environment mirror spatial gradients, it opens up potential for predicting course adaptive evolution over time based on patterns genetic and phenotypic variation. We assessed this approach 30-year transplant experiment intertidal snail Littorina saxatilis . In 1992, snails were transplanted from predation-dominated to one dominated by wave action. On basis patterns, we predicted transitions...

10.1126/sciadv.adp2102 article EN cc-by-nc Science Advances 2024-10-11

In the Chilean Frontal Cordillera between 28.5 and 30.5° S, two volcano-sedimentary succesions of Late Guadalupian to Middle Triassic age croup out: El Tapado (Late Guadalupian-Lopingian) Guanaco Sonso Lopingian-Middle Triassic) formations, representing westernmost exposures Choiyoi Group post-Choiyoi magmatism. Recently, these units have been characterized in detail, shedding light into tectonic climatic context late stages magmatism, and, more generally, geology intra-arc successions...

10.5027/andgeov52n1-3689 article EN cc-by Andean geology 2025-01-31

Abstract Summary: Development of effective tools such as oligo-microarrays and next-generation sequencing methods for monitoring gene expression on a large scale has resulted in the discovery signatures with prognostic/predictive value various malignant neoplastic diseases. However, exponential growth databases, biologists are faced challenge extracting useful information from these repositories. Here, we present software package, BioPlat (Biomarkers Platform), which allows to identify novel...

10.1093/bioinformatics/btu111 article EN Bioinformatics 2014-02-25

Abstract Key innovations are fundamental to biological diversification, but their genetic architecture is poorly understood. A recent transition from egg-laying live-bearing in Littorina snails provides the opportunity study of an innovation that has evolved repeatedly animals. Samples do not cluster by reproductive mode a genome-wide phylogeny, local genealogical analysis revealed numerous genomic regions where all live-bearers carry same core haplotype. Associated show evidence for...

10.1101/2023.02.13.528213 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2023-02-13

Abstract Predicting the outcomes of adaptation is a major goal evolutionary biology. When temporal changes in environment mirror spatial gradients, it opens up potential for predicting course adaptive evolution over time based on patterns genetic and phenotypic variation. We assessed this approach 30-year transplant experiment marine snail Littorina saxatilis . In 1992, snails were transplanted from predation-dominated to one dominated by wave action. Based patterns, we predicted transitions...

10.1101/2023.09.27.559715 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2023-09-29

Common wheat (Triticum aestivum) is a hexaploid plant (AABBDD) derived from genetically related tetraploid T. turgidum (AABB) and diploid goatgrass Aegilops tauschii (DD). Recent advances in sequencing technology genome assembly strategies allow the acquisition of multiple genomes, calling for centralized database to store, manage query genomics information manner reflect their evolutionary relationship perform effective comparative analysis. Here, we built WheatGene, that contains five...

10.1016/j.cj.2021.04.011 article EN cc-by-nc-nd The Crop Journal 2021-06-13
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