Chris B. Agala

ORCID: 0000-0001-7157-814X
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About
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Research Areas
  • Breast Cancer Treatment Studies
  • HIV/AIDS Research and Interventions
  • Burn Injury Management and Outcomes
  • Colorectal Cancer Surgical Treatments
  • Breast Lesions and Carcinomas
  • Peripheral Artery Disease Management
  • COVID-19 and healthcare impacts
  • HIV, Drug Use, Sexual Risk
  • Adolescent Sexual and Reproductive Health
  • Mechanical Circulatory Support Devices
  • Cardiac, Anesthesia and Surgical Outcomes
  • Bariatric Surgery and Outcomes
  • Congenital Heart Disease Studies
  • Trauma and Emergency Care Studies
  • Inflammatory Bowel Disease
  • Cardiac Structural Anomalies and Repair
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Tracheal and airway disorders
  • HIV-related health complications and treatments
  • Advanced Breast Cancer Therapies
  • Esophageal and GI Pathology
  • Lung Cancer Treatments and Mutations
  • HER2/EGFR in Cancer Research
  • Traumatic Brain Injury Research
  • Diversity and Career in Medicine

University of North Carolina at Chapel Hill
2016-2025

University of North Carolina at Charlotte
2025

University of Colorado Anschutz Medical Campus
2024

University of North Carolina Health Care
2022-2024

University of North Carolina Hospitals
2023

Duke University Hospital
2022-2023

Howard University
2023

University of Nebraska Medical Center
2022

China Population and Development Research Center
2018-2019

Thomas University
2018

Patients with metastatic melanoma to the lung typically have poor outcomes. Although a pulmonary metastasectomy for selected patients has been shown improve survival, role of surgical resection following introduction immunotherapy is unknown. The objective this study was determine predictors survival in era immunotherapy. In retrospective study, data from National Cancer Database were abstracted metastases. overall evaluated using Kaplan-Meier and Cox proportional hazard analysis, adjusting...

10.3390/cancers17020206 article EN Cancers 2025-01-10

In Kenya in 1999, an estimated 6.9% of women nationally said they had exchanged sex for money, gifts or favours the previous year. 2000 and 2001, collaboration with workers who formed a network self-help groups, we conducted exploratory survey among 475 four rural towns three Nairobi townships, regarding where worked, number clients risks were exposed to. Participants identified by social contacts seven centres. Most (88%) worked from bars, hotels, bus stages discos; 57% lived stable partner...

10.1016/s0968-8080(04)23125-1 article FR Reproductive Health Matters 2004-01-01

As antiretroviral therapy (ART) for HIV becomes increasingly available in low and middle income countries (LMICs), understanding reasons lack of adherence is critical to stemming the tide infections improving health. Understanding effect psychosocial experiences mental health symptomatology on ART can help maximize benefit expanded programs by indicating types services, which could be offered combination with care.The Coping HIV/AIDS Tanzania (CHAT) study a longitudinal cohort Kilimanjaro...

10.1371/journal.pone.0074771 article EN cc-by PLoS ONE 2013-10-04

Abstract Background Poor oral health has been identified as a prognostic factor potentially affecting the survival of patients with head and neck squamous cell carcinoma. However, evidence to date supporting this association emanated from studies based on single cohorts small-to-modest sample sizes. Methods Pooled analysis 2449 carcinoma participants 4 International Head Neck Cancer Epidemiology Consortium included data periodontal disease, tooth brushing frequency, mouthwash use, numbers...

10.1093/jnci/djad156 article EN cc-by JNCI Journal of the National Cancer Institute 2023-09-19

Abstract Background Sleeve gastrectomy (SG) increased in popularity after 2010 but recent data suggest it has concerning rates of gastroesophageal reflux and need for conversions. This study aims to evaluate trends the utilization bariatric procedures, associated complications, conversions using an administrative claims database United States. Methods We included adults who had procedures from 2000 2020 with continuous enrollment at least 6 months MarketScan Commercial Claims Encounters...

10.1007/s00464-024-10985-7 article EN cc-by Surgical Endoscopy 2024-06-20

Background In high income nations, traumatic life experiences such as childhood sexual abuse are much more common in people living with HIV/AIDS (PLWHA) than the general population, and trauma is associated worse current health functioning. Virtually no data exist on prevalence or consequences of for PLWHA low nations. Methodology/Principal Findings We recruited four cohorts Tanzanian patients established medical care HIV infection (n = 228), individuals newly testing positive 267), negative...

10.1371/journal.pone.0036304 article EN cc-by PLoS ONE 2012-05-14

24 Background: Given noted heterogeneity in Hispanic adults, cancer outcomes reported aggregate may not detect disparities within specific subgroups. The objective was to assess whether any potential differences colon (CC) stage at diagnosis among patients with background (HBackground) could be explained by socio-economic determinants of health (SDOH) including income, education and insurance status. Methods: National Cancer Database queried for diagnosed CC from 2004 2021. Two logistic...

10.1200/jco.2025.43.4_suppl.24 article EN Journal of Clinical Oncology 2025-01-27

To evaluate the bleeding risk associated with anticoagulation (AC) in kidney transplant patients post-operative atrial fibrillation (AF). We conducted a retrospective analysis of all adult recipients performed from October 2012 to February 2019 at our institution, University North Carolina Chapel Hill, which accounted for 428 transplants. Variables assessed included AF occurrence, AC use, complications, stroke and stratification (determined using...

10.21926/obm.transplant.2501238 article EN OBM Transplantation 2025-02-27

Background: Obesity increases the risks for perioperative complications and recurrence after ventral hernia repairs (VHR). The effect of bariatric surgery itself on VHR has not been widely studied. This study uses MarketScan ® database to evaluate outcomes elective following a history surgery. Methods: IBM Commercial Database (2000-2021) was used identify patients with (bariatric group) or without but were otherwise obese (obese control group). Propensity score weighting balance measured...

10.1177/00031348251341941 article EN The American Surgeon 2025-05-21

Linkage to HIV care is crucial the success of antiretroviral therapy (ART) programs worldwide, loss follow up at all stages continuum frequent, and long-term prospective studies linkage are currently lacking.Consecutive clients who tested HIV-positive were enrolled from four testing centers (1 health facility 3 community-based centers) in Kilimanjaro region Tanzania as part larger Coping with HIV/AIDS (CHAT) observational study. Biannual interviews conducted over 3.5 years, assessing...

10.1186/s12879-016-1804-8 article EN cc-by BMC Infectious Diseases 2016-09-20

Background: The current National Comprehensive Cancer Network advises neoadjuvant chemoradiotherapy followed by surgery for locally advanced cases of esophageal cancer. role immunotherapy in this context is under heavy investigation. Methods: Patients with adenocarcinoma were identified the Database (NCDB) from 2004 to 2019. Three groups generated as follows: (a) no immunotherapy, (b) and (c) adjuvant immunotherapy. Overall survival was evaluated using Kaplan–Meier method Cox proportional...

10.3390/cancers16132460 article EN Cancers 2024-07-04

The burden of congenital gastrointestinal (GI) anomalies is poorly understood. aim this systematic review to assess the global prevalence anomalies. We conducted a population-level birth gastroschisis, omphalocele, intestinal atresia, esophageal diaphragmatic hernia, Hirschsprung’s disease, and anorectal malformation. identified 103 studies from high middle-income countries. Gastroschisis was most reported condition. Studies geographic heterogeneity in malformation prevalence. disease have...

10.1177/30502225251304582 article EN 2025-02-01

Objective . Birth prevalence estimates for major congenital gastrointestinal anomalies are sparse. This paper serves as an in-depth, a priori systematic review protocol our identifying and assessing studies reporting population-level birth anomalies. Methods We will use the Condition, Context, Population framework include of gastroschisis, omphalocele, intestinal esophageal atresia, Hirschsprung’s disease, diaphragmatic hernia, anorectal malformation in infants. assess bias using Joanna...

10.1177/30502225251283177 article EN 2025-02-01

Abstract Background Adherence to antiretroviral therapy is critical the achievement of third target UNAIDS Fast-Track Initiative goals 2020–2030. Reliable, valid and accurate measurement adherence are important for correct assessment in predicting efficacy ART. The Simplified Medication Questionnaire a six-item scale which assesses perception persons living with HIV about their Despite recent widespread use, its properties have yet be carefully documented beyond original study Spain....

10.1186/s12889-020-08585-w article EN cc-by BMC Public Health 2020-04-28

Background & Aims: Early-stage HCC can be treated with thermal ablation or stereotactic body radiation therapy (SBRT). We retrospectively compared local progression, mortality, and toxicity among patients SBRT in a multicenter, US cohort. Approach Results: included adult treatment-naïve lesions without vascular invasion per individual physician institutional preference from January 2012 to December 2018. Outcomes progression after 3-month landmark period assessed at the lesion level...

10.1097/hc9.0000000000000184 article EN cc-by-nc-nd Hepatology Communications 2023-06-14
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