A5023690902- Nanoparticle-Based Drug Delivery
- Nanoplatforms for cancer theranostics
- Ultrasound and Hyperthermia Applications
- Radiation Therapy and Dosimetry
- Graphene and Nanomaterials Applications
- RNA Interference and Gene Delivery
- Glioma Diagnosis and Treatment
- SARS-CoV-2 and COVID-19 Research
- Gold and Silver Nanoparticles Synthesis and Applications
- Graphene research and applications
- Nanoparticles: synthesis and applications
- Autophagy in Disease and Therapy
- Photochromic and Fluorescence Chemistry
- Effects of Radiation Exposure
- Circular RNAs in diseases
- MicroRNA in disease regulation
- COVID-19 Clinical Research Studies
- Intracranial Aneurysms: Treatment and Complications
- Cancer, Lipids, and Metabolism
- Ultrasound and Cavitation Phenomena
- COVID-19 diagnosis using AI
- Boron Compounds in Chemistry
- Trace Elements in Health
- Health and Well-being Studies
- Musculoskeletal pain and rehabilitation
Iran University of Medical Sciences
2017-2024
Tabriz University of Medical Sciences
2021
Zahedan University of Medical Sciences
2021
Medical University of Ilam
2020
Tumor-selective photodynamic therapy is a successful method for ablation of malignant and cancerous cells. Herein, we introduce the design preparation functionalized acrylic copolymer nanoparticles with spiropyran (SP) imidazole groups through facile semicontinuous emulsion polymerization. Then, Au3+ ions were immobilized reduced on their surface to obtain photoresponsive gold-decorated polymer (PGPNPs). The prepared PGPNPs surface-modified folic acid as site-specific tumor cell targeting...
In recent times, the intersection of nanotechnology and biomedical research has given rise to nanobiomedicine, a captivating realm that holds immense promise for revolutionizing diagnostic therapeutic approaches in field cancer. This innovative fusion biology, medicine, aims create agents with enhanced safety efficacy, particularly theranostics various malignancies. Diverse inorganic, organic, hybrid organic-inorganic nanoparticles, each possessing unique properties, have been introduced...
In order to conduct an effective chemotherapy session as a treatment modality for glioblastoma tumors, nanocarrier platform is required the drug cross blood brain barrier (BBB) successfully and properly target glioma cells. Dual-targeting Temozolomide (TMZ) loaded triblock polymer coated magnetic nanoparticles (MNPs) were synthesized with SPION core by conjugating surface folic acid (FA), which shown effectively pass BBB tumor Two principal methods, dynamic light scattering (DLS)...
Prostate cancer is the second most frequent type of death in men. This study refers to novel hyperthermia application poloxamer-coated cobalt ferrite as a new approach for thermal eradication DU-145 human prostate cancerous cells under radio frequency magnetic field (RF-MF). The hydrothermal method was applied synthesis nanoparticles. Then, structure, size, and morphology nanoparticle were characterized. cytotoxicity synthesized nanoparticles RF-MF exposure on investigated separately or...
Abstract Background In the current study, folic acid-conjugated PEG-PCL-PEG triblock copolymer were synthesized and loaded with 5-fluorouracil magnetite nanoparticles (5-FU-SPION-PEG-PCL-PEG-FA) for targeted delivery of drug to HT29 human colon cancer cells CT26 mouse model. The characterized by nuclear magnetic resonance spectroscopy (NMR) transmission electron microscopy (TEM). cellular uptake was assessed in vitro (on HUVEC HT29) vivo tumor tissues). cytotoxic effect on cell lines (HT29,...
Doxorubicin loaded magnetic Janus nanoparticles coated with PCL and chitosan modified folic acid fluorescein were able to pass the blood brain-barrier via external field ligand–receptor interaction.
Despite the development of conventional therapies including surgery, radiotherapy, chemotherapy and hyperthermia, prognosis remains very poor. Recently, integration therapy multifunctional nanoparticles have attracted a lot attention because it produces synergistic effect better diagnostic therapeutic efficiency.This study aimed to investigate uptake cytotoxic effects Polycaprolactone (PCL)/chitosan (CHI)-coated Superparamagnetic Iron Oxide Nano-Graphene (SPION-NGO) as carrier 5-fluorouracil...
Glioblastoma multiform (GBM) is the most prevalent and aggressive type of primary brain tumor. None current conventional treatment methods has improved considerably. Therefore, in this study effect magnetic nanoparticles coated with poly (caprolactone)-poly (ethylene glycol) (PCL-PEG) as a 5-iodo 2'deoxyuridine (IUdR) carrier presence hyperthermia 6 MV (megavoltage) X-ray radiation, were investigated spheroid model U87MG glioblastoma cell line using colony formation assay.First, human was...
This study reports a new procedure for utilizing 5-fluorouracil (5-Fu)-loaded polycaprolactone (PCL)/chitosan-covered magnetite nanographene oxide (5-Fu/SPION/NGO@PCL–LMWC) as platform synergistic thermo–chemotherapy. In fact, superparamagnetic iron nanoparticles/nanographene (SPION/NGO) nanoparticles can be coated with copolymers PCL/chitosan to attain better colloidal stability in the biological environment. Nanoparticles were synthesized and characterized their size, surface charge, X-ray...
Abstract Background As a radiosensitizing agent in magnetic resonance imaging (MRI), gadolinium is disadvantageous that it confers rather high toxicity and low longitudinal comfort time (r 1 ). We hypothesized when combined with gold-coated iron oxide nanoparticles (NPs), might deliver better radiosensitization MRI-based cancer theranostics. After being synthesized ligand/receptor RGD@Fe 3 O 4 -Au/Gd nanoparticles, they were characterized via some methods, such as visible–ultraviolet...