A5069583475- Veterinary Oncology Research
- Neutropenia and Cancer Infections
- Infectious Diseases and Mycology
- Hematopoietic Stem Cell Transplantation
- Hematological disorders and diagnostics
- Salivary Gland Tumors Diagnosis and Treatment
- Inflammatory Myopathies and Dermatomyositis
- Virus-based gene therapy research
- Myasthenia Gravis and Thymoma
- Autoimmune Bullous Skin Diseases
- Oral health in cancer treatment
- Tumors and Oncological Cases
- Blood disorders and treatments
- Veterinary Medicine and Surgery
- Surgical site infection prevention
- Ovarian cancer diagnosis and treatment
Roslin Institute
2017-2020
University of Edinburgh
2017-2020
Fine-needle aspiration cytology (FNAC) of lymph nodes (LNs) is routinely used for staging canine malignant solid tumors, but studies evaluating its efficacy are limited.The primary objectives this study were to evaluate the sensitivity/specificity FNAC and significance nondiagnostic when tumors. A secondary objective was determine prevalence multiple nodal metastases.Lymph draining tumors assessed with histopathology included. The determined LNs diagnostic FNAC, using as gold standard....
Peripheral nodal B-cell lymphomas (PNBCL) represent the most common presentation of in dogs. Multiagent CHOP (C = cyclophosphamide, H hydroxydaunorubicin [Doxorubicin], O Oncovin, P prednisolone)-based chemotherapy protocols have been widely accepted as gold standard 1st-line treatment. CHOP-25 and CHOP-19 are commonly prescribed but never directly compared.
Canine mast cell tumours (MCTs) typically spread to lymph nodes (LNs) before reaching distant sites, and LN assessment is an important part of MCT staging. Sentinel (SLN) mapping techniques identify draining LNs are being developed could improve the accuracy The primary objective this feasibility study was determine safety effectiveness contrast-enhanced ultrasound (CEUS) SLNs. Secondary objectives were if SLNs identified by CEUS coincided with regional predicted anatomical lymphosomes,...
Background Prechemotherapy absolute neutrophil count ( ANC ) cutoffs are arbitrary and vary across institutions clinicians. Similarly, subjective guidelines utilized for the administration of prophylactic antibiotics in neutropenic dogs. Objectives To evaluate impact various on chemotherapy dogs with lymphoma treated CHOP to determine whether an association between prechemotherapy subsequent toxicity exists. The secondary objective was a currently used cutoff indicate prescription...
Abstract Absolute neutrophil count (ANC) cut‐offs for antimicrobial prophylaxis in veterinary cancer chemotherapy patients are empirical and vary between institutions. Evidence based vital stewardship, particularly as global resistance rises. The primary objectives of this study were to evaluate the tolerability a <0.75 × 10 9 /l ANC cut‐off dogs after receiving its impact on prescription. Predicted nadir ANCs (pnANCs) stratified into six groups (<0.75 [receiving prophylaxis],...
Chemotherapy-induced diarrhoea (CID) is a frequent chemotherapy adverse event in dogs. Yet, there currently no consensus regarding its management. Smectite natural medical clay, widely used the treatment of acute humans. The objectives this study were to assess efficacy smectite management CID dogs, and collect epidemiological data on CID. For each episode diarrhoea, dogs randomized into two groups: group, receiving at 0.5 g/kg PO per day divided three doses initiated start CID; control...
Neutropenia is a common chemotherapy-associated adverse event (AE) in dogs and significant cause of decreased relative dose intensity. Dose reductions (DRs) treatment delays (TDs) are frequently applied to decrease the risk further neutropenic events (NEs) AEs, but there no standardised approach. The two main objectives this retrospective study were determine: (1) failure rate 10% DR prevent subsequent inadequate absolute neutrophil count (ANC), defined as nadir ANC <0.75 × 10
Exfoliative dermatitis is a well-recognized cutaneous paraneoplastic syndrome (PNS) associated with thymoma in cats, of which the clinical and histopathological presentation has been well-characterized.To describe novel skin manifestation cat.A 14-year-old neutered female domestic short hair cat.Physical, abdominal ultrasonographic, thoracic radiographic, ultrasonographic computed tomographic examinations, assessment mediastinal mass.The cat was presented noninflammatory alopecia, dorsal...
The aim of this retrospective multicentric case series is to describe the CT findings ovarian neoplasia in dogs. Twenty dogs with pre- and postcontrast exams cytological/histological diagnosis were included. Five presented bilateral tumors, for a total 25 neoplasms: 15 carcinomas (4 bilateral), 4 granulosa cell 2 poorly differentiated malignant (bilateral), luteomas, 1 teratoma, dysgerminoma. In two dogs, tumor developed from an remnant. Ovarian tumors showed variable size, lobulated shape,...