- Veterinary Oncology Research
- Infectious Diseases and Mycology
- Microbial infections and disease research
- Diagnosis and treatment of tuberculosis
- Virus-based gene therapy research
- Veterinary Medicine and Surgery
- Salivary Gland Tumors Diagnosis and Treatment
- Fungal Infections and Studies
- Herpesvirus Infections and Treatments
- Medical Imaging and Pathology Studies
- Antifungal resistance and susceptibility
- T-cell and B-cell Immunology
- Oral and Maxillofacial Pathology
- Vector-Borne Animal Diseases
- Mycobacterium research and diagnosis
- Bird parasitology and diseases
- Bladder and Urothelial Cancer Treatments
- Erythrocyte Function and Pathophysiology
- Animal health and immunology
- Lymphoma Diagnosis and Treatment
- Chemokine receptors and signaling
- Polyomavirus and related diseases
- Pediatric Urology and Nephrology Studies
- Gastrointestinal Tumor Research and Treatment
- Occupational and environmental lung diseases
University of Edinburgh
2016-2022
Roslin Institute
2018-2020
University of Georgia
2012-2019
University of Glasgow
2015-2019
Massachusetts Institute of Technology
2016-2019
Zoo New England
2019
Med Center
2019
Texas A&M University
2017
Colorado State University
2017
Smithsonian Conservation Biology Institute
2017
Fine-needle aspiration cytology (FNAC) of lymph nodes (LNs) is routinely used for staging canine malignant solid tumors, but studies evaluating its efficacy are limited.The primary objectives this study were to evaluate the sensitivity/specificity FNAC and significance nondiagnostic when tumors. A secondary objective was determine prevalence multiple nodal metastases.Lymph draining tumors assessed with histopathology included. The determined LNs diagnostic FNAC, using as gold standard....
Canine mast cell tumours (MCTs) typically spread to lymph nodes (LNs) before reaching distant sites, and LN assessment is an important part of MCT staging. Sentinel (SLN) mapping techniques identify draining LNs are being developed could improve the accuracy The primary objective this feasibility study was determine safety effectiveness contrast-enhanced ultrasound (CEUS) SLNs. Secondary objectives were if SLNs identified by CEUS coincided with regional predicted anatomical lymphosomes,...
Inflammatory bowel disease (IBD) is a common disorder of ferrets ( Mustela putorius furo) that may progress to lymphoma. Although routine histology used distinguish between these diseases, misclassifications occur. Immunohistochemistry (IHC) commonly IBD and lymphoma in small animals. The objective our study was determine the agreement diagnosis reached solely using hematoxylin eosin (HE)-stained, full-thickness sections versus combination HE IHC. Enteric from 44 previously diagnosed with or...
Retrobulbar neoplasms are not common in mammals and even more infrequently seen nonmammalian species. The current report describes a retrobulbar mass creating exophthalmia neurologic signs red-lored Amazon parrot ( Amazona autumnalis). A 27-year-old female presented for 3-day history of anorexia 2-week periocular soft tissue swelling the right eye. Physical examination revealed 9% dehydration eye with inability to retropulse globe. fine-needle aspirate was performed, cytologic evaluation...
Mycobacterial infections are a major concern in veterinary medicine because of the difficulty achieving an etiological diagnosis, challenges and concerns treatment, potential zoonotic risk.
Determining the cause of effusions is challenging and might require a biopsy. Whether cell blocks from are representative biopsies requires investigation. A previously developed immunohistochemical panel aids in differentiation hyperplastic neoplastic mesothelium canine but has not been investigated effusions.The study aimed to assess as an alternative determine whether immunohistochemistry helps distinguish mesothelium, mesothelioma, carcinoma.Effusions were collected five dogs with...
Neoplasia is usually encountered in the African pygmy hedgehog at a mean age of 3.5 y, and malignancy common. Myelogenous leukemias are rarely reported hedgehogs. We describe 3 cases eosinophilic leukemia adult, middle-aged (mean age: 2.3 y) hedgehogs, for which prognosis appears grave. In 1 case, attempted treatment was unsuccessful, all cases, disease course rapid died soon after diagnosis. Blood smear evaluation, along with complete blood count, critical making diagnosis cases. Luna stain...
A 2.5-year-old, male, neutered cat presented with a 5-month history of progressive right hind limb lameness and an enlarged popliteal lymph node. Radiographs revealed significant bony lysis the tarsus distal tibia, fine-needle aspirate bone lesion node neoplastic population cells uncertain origin. Amputation was elected, mass submitted for histology cellular culture better characterization. Histologic examination mixture spindle-shaped larger, round to polygonal cells. All were...
Introduction. Infection with the Rasamsonia argillacea species complex represents an emerging problem in human and veterinary medicine systemic mycoses presenting significant clinical complications being a cause of death. Case presentation. In this report, case piperina infection discovered 3-year-old male neutered, German shepherd cross dog is described together presentation, course disease diagnosis. This report describes first mycosis due to R. Europe humans or animals UK. Conclusion....
Endogenous lipoid pneumonia is a poorly characterised condition in veterinary medicine, particularly dogs, but it well recognised association with lung neoplasia humans. This case series describes three unique cases of endogenous associated neoplasia, including clinical, imaging, cytological findings and outcome. Clinical presentation imaging lesions can appear non‐specific may be obscured by neoplastic infiltrate so diagnosis requires cytology or histopathology. Awareness dogs pulmonary has...
Blood smears from a 24-year-old male rhesus macaque ( Macaca mulatta) used for cognitive function studies were evaluated. The had an 8-month history of gradual weight loss and increasing lymphocytosis. Most the lymphocytes present small to medium mature morphology. Based on degree duration lymphocytosis, appearance lymphocytes, diagnosis chronic lymphocytic leukemia was made. animal tested negative 4 viral diseases that are commonly associated with lymphoproliferative disorders in Old World...
The authors have indicated that they no affiliations or financial involvement with any organization entity a interest in, in competition with, the subject matter materials discussed this article.
Inflammatory bowel disease (IBD) is an idiopathic, chronic, inflammatory of the gastrointestinal tract companion animals, including ferrets ( Mustela putorius furo). Clinical signs IBD are nonspecific, and intestinal biopsies necessary for a definitive diagnosis. A grading scheme has not been established ferrets. Additionally, association between histologic severity clinical in unknown. We evaluated enteric samples from diagnosed with IBD, compared schemes, correlated results signs. Enteric...
Abstract A 2‐year‐old female intact African pygmy hedgehog was presented for diagnostic investigation of a 2‐month reduction in appetite, with weight loss and recent vomiting. Clinical examination revealed large, firm mass originating from the left cranial abdomen. Ultrasound‐guided fine‐needle aspirates mass, liver, mesenteric lymph nodes population pleomorphic round cells, some which contained variable numbers round, clear vacuoles, consistent diagnosis lymphoma Mott cell differentiation....
This case series discusses novel characteristics identified in two cases of cowpox. One presented with upper airway signs, and was to have a focal laryngeal lesion. The other had central neurological signs at the terminal stages, intracytoplasmic inclusion bodies within cerebral hemispheres on histopathology.Currently, cowpox would be an unlikely consideration patients or respiratory noise. These both document presentations infection, which clinicians should aware consider as differential...
A 7-year-old 26.0-kg (57.2-lb) castrated male Boxer was evaluated because of vomiting, excretion dark tarry feces, and weight loss 10 days' duration.The dog reported to be intermittently inappetent during the week preceding evaluation.Five months prior, osteosarcoma distal portion left radius had been diagnosed treated with complete forelimb amputation.The recovered from this procedure no postoperative complications.Thoracic radiography at time surgery did not reveal any evidence metastatic...