Clinical relevance: In contrast to superficial fungal infections, such as dermatophytosis, invasive infections (IFIs) are characterised by penetration of tissues elements. Disease can spread locally within a region or disseminate haematogenously via the lymphatics. The environment is most common reservoir infection. Since spores airborne, indoor cats also susceptible IFIs. Some environmental fungi ubiquitous and present globally, while others endemic hyperendemic specific geographic regions....

Clinical relevance: Invasive fungal infections (IFIs) and oomycoses (hereafter termed invasive fungal-like [IFLIs]) are characterised by penetration of tissues elements. The environment is the most common reservoir infection. IFIs IFLIs can be frustrating to treat because long treatment times usually required and, even after attaining clinical cure, there may a risk relapse. Owner compliance with medication administration recheck examinations also decline over time. In addition, some...

Despite over 25 years of feline immunodeficiency virus (FIV) research, relatively little is known about the longitudinal course FIV infection following natural infection. In contrast to published reports experimental infections using lethal strains virus, clinical signs naturally acquired can be mild or inapparent, rather than life-threatening. this prospective, controlled study, based in Chicago, IL (n = 17) and Memphis, TN 27), we investigated two cohorts privately owned, infected cats...

Malassezia are members of the mycobiome dogs and cats. In presence an underlying disease, these yeasts can proliferate, attach to skin or mucosa induce a secondary dermatitis, otitis externa paronychia. Since allergic dermatitis is one most common causes, diagnostic investigation for allergy often indicated. Cats may suffer from various other problems, especially where generalised. in cats chronic, relapsing pruritic. Direct cytology dermatological lesions ear canal, showing "peanut-shaped"...

Babesia gibsoni is an intra-erythrocytic protozoan responsible for the most common arthropod-borne infection affecting dogs in Hong Kong. This study describes clinical findings and determines clinicopathological alterations hematology, serum biochemistry, urinalysis, coagulation profile of infected dogs. A retrospective analysis was conducted on 108 presented to emergency specialty hospital Kong from 2012 2022. Each dog had a positive polymerase chain reaction (PCR) diagnosis complete...

Brachycephalic dogs are not only affected by brachycephalic obstructive airway syndrome (BOAS), but also comprise up to 30% of canine patients seen veterinary dermatologists, with English Bulldogs and Pugs particularly overrepresented. Some skin diseases associated the abnormal anatomic conformation dogs, while for others there is a underlying genetic basis or general predisposition. Anatomic alterations brachycephaly, leading fold formation stenosis ear canal, together primary...

Across human and veterinary medicine, vaccines against only two retroviral infections have been brought to market successfully, the feline leukaemia virus (FeLV) immunodeficiency (FIV). FeLV a global success story, reducing prevalence in countries where uptake is high. In contrast, more recent FIV vaccine was introduced 2002 degree of protection afforded field remains be established. However, given similarities between HIV, studies efficacy are likely advise inform development future...

Recombination is a common feature of retroviral biology and one the most important factors responsible for generating viral diversity at both intra-host population levels. However, relatively little known about rates molecular processes recombination retroviruses other than HIV, including model viruses such as feline immunodeficiency virus (FIV). We investigated in complete FIV env gene sequences (n = 355) isolated from 43 naturally infected cats. demonstrated that abundant natural...

Tick-borne haemoparasite Babesia gibsoni has been detected rarely in cats, surveys of apparently healthy animals. In stored blood from a 6-year-old male-neutered domestic shorthair cat Hong Kong, B. DNA was retrospectively using PCR for spp. 18S rRNA and mitochondrial cytochrome B genes, followed by sequencing basic local alignment search tool (BLAST) analysis. The presented with severe haemolytic anaemia thrombocytopenia. responded to supportive care glucocorticoids clinically normal...

Based on clinical observations and the increasing number of published reports, it is evident that many feline immunodeficiency virus (FIV)-positive cats display mild or inapparent signs frequently achieve normal life spans. Although manifestation infection determined by unknown viral, host, environmental factors, relative intrahost genetic stability FIV may play an important role in apparent observed naturally infected cats. Performance commercial Fel-O-Vax vaccine documented recent field...

Background Infection with feline immunodeficiency virus (FIV) is mediated by attachment to CD134 (OX40) followed a second interaction CXCR4, the sole co-receptor for infection. However, in vivo cell tropism of FIV expands time post-infection, analogous shift observed HIV-1 as usage switches from CCR5 CXCR4. Here, we ask whether alterations Env-CD134 underpin and this associated disease progression.

Analysing the evolution of feline immunodeficiency virus (FIV) at intra-host level is important in order to address whether diversity and composition viral quasispecies affect disease progression. We examined evolutionary rates entire env structural fragments sequences obtained from sequential blood samples 43 naturally infected domestic cats that displayed different clinical outcomes. observed majority FIV showed very low levels diversity. estimated evolved a rate 1.16×10 −3 substitutions...

Small animal caregivers' perceptions and previous life experiences play a pivotal role in patient care, making effective communication fundamental within the veterinary business. Despite large growing scale of pet industry, data on small client-centered information about services Mainland China (MC) Hong Kong Special Administrative Region (HKSAR) are lacking. The objective this study was to investigate opinions caregivers surgery, pain management, anesthesia dogs cats these geographical...

Myelolipoma is a benign, typically inert neoplasm of uncertain aetiology that rarely reported in cats. Although commonly asymptomatic, some cases, myelolipomas can cause abdominal discomfort or present with rupture and haemorrhage. Here, we describe rare case splenic myelolipoma Domestic Long Hair cat which, after extensive diagnostic investigations, clinical signs hyporexia weight loss were attributable to the presence an intra-abdominal mass. The patient was treated by splenectomy...

Feline immunodeficiency virus (FIV) infection is mediated by sequential interactions with CD134 and CXCR4. Field strains of vary in their dependence on cysteine-rich domain 2 (CRD2) for infection. Here, we analyse the receptor usage viral variants blood 39 naturally infected cats, revealing that CRD2-dependent dominate early infection, evolving towards CRD2-independence disease progression. These findings are consistent a shift CRD2

Canine hemangiosarcoma (HSA) is a relatively common neoplasia, occurring mainly in the skin, spleen, liver and right atrium. Despite numerous studies investigating treatment of canine HSA, no significant improvement survival has been achieved last 20 years. Advancements genetic molecular profiling presented similarities HSA with human angiosarcoma. It could therefore serve as valuable model for new more effective treatments people dogs. The most abnormalities have found...

Background3 Definition3 Using the List of Essential Medicines3 Criteria for Selection Anaesthetic, Analgesic, Sedative and Emergency Drugs4 Antimicrobial Drugs6 Antibacterial Antiprotozoal Systemic Administration6 Topical Administration7 Antifungal Drugs7 Antiparasitic Antiviral Drugs8 Behaviour Modifying Therapies9 Cardiorespiratory Renal Systems9 Endocrinology10 Euthanasia Drugs11 Gastrointestinal System11 Immunomodulatory Neurology12 Oncology12 Ophthalmology13 Reproduction14 Vaccines14...

Neutralizing antibodies (NAbs) are believed to comprise an essential component of the protective immune response induced by vaccines against feline immunodeficiency virus (FIV) and human (HIV) infections. However, relatively little is known about role NAbs in controlling FIV infection subsequent disease progression. Here, we present studies where examined neutralization HIV-luciferase pseudotypes bearing homologous heterologous envelope proteins ( n = 278) sequential plasma samples collected...

Free accessAbstractFirst published online August 25, 2015Clinical/research abstracts accepted for presentation at ISFM Congress 2015All Articleshttps://doi.org/10.1177/1098612X15594997