A5090912033- Antifungal resistance and susceptibility
- Infectious Diseases and Mycology
- Fungal Infections and Studies
- Mycotoxins in Agriculture and Food
- Memory Processes and Influences
- Plant Pathogens and Fungal Diseases
- Identity, Memory, and Therapy
- Microbial infections and disease research
- Memory and Neural Mechanisms
- Creativity in Education and Neuroscience
- Veterinary Oncology Research
- Nail Diseases and Treatments
- Human-Animal Interaction Studies
- Traumatic Brain Injury Research
- Inhalation and Respiratory Drug Delivery
- Stalking, Cyberstalking, and Harassment
- Visual Attention and Saliency Detection
- Torture, Ethics, and Law
- Craniofacial Disorders and Treatments
- Jury Decision Making Processes
- Cleft Lip and Palate Research
- Neurogenetic and Muscular Disorders Research
- Research on Leishmaniasis Studies
- Action Observation and Synchronization
- Face Recognition and Perception
Sapienza University of Rome
2022-2025
Lismore Base Hospital
2024
The University of Sydney
2012-2021
Hull City Council
2020
Jacksonville University
2019
Taronga Conservation Society Australia
2017
Clinical relevance: In contrast to superficial fungal infections, such as dermatophytosis, invasive infections (IFIs) are characterised by penetration of tissues elements. Disease can spread locally within a region or disseminate haematogenously via the lymphatics. The environment is most common reservoir infection. Since spores airborne, indoor cats also susceptible IFIs. Some environmental fungi ubiquitous and present globally, while others endemic hyperendemic specific geographic regions....
Although Aspergillus fumigatus is the major agent of invasive aspergillosis, an increasing number infections are caused by its cryptic species, especially A. lentulus and viridinutans species complex (AVSC).Their identification clinically relevant because antifungal drug resistance refractory infections.Species boundaries in AVSC unresolved since most have uniform morphology produce interspecific hybrids vitro.Clinical environmental strains from six continents (n = 110) were characterized...
The prevalence of azole resistance in Aspergillus fumigatus is uncertain Australia. Azole exposure may select for resistance. We investigated the frequency a large number clinical and environmental isolates.A. isolates [148 human, 21 animal 185 strains from air (n = 6) azole-exposed 64) or azole-naive 115) environments] were screened using VIPcheck™ system. MICs determined Sensititre™ YeastOne YO10 assay. Sequencing cyp51A gene promoter region was performed azole-resistant isolates, homology...
Summary Azole‐resistant environmental Aspergillus fumigatus presents a threat to public health but the extent of this in Southeast Asia is poorly described. We conducted surveillance Mekong Delta region Vietnam, collecting air and ground samples across key land‐use types, determined antifungal susceptibilities section Fumigati (ASF) isolates azole concentrations soils. Of 119 ASF isolates, 55% were resistant (or non‐wild type) itraconazole, 65% posaconazole 50% voriconazole. Azole resistance...
Individuals who possess a Highly Superior Autobiographical Memory (HSAM) can remember their own lives in exceptional detail, retrieving specific autobiographical events response to dates (e.g., 15th April 1995). The phenomenon remains extremely rare, and little is known about why these individuals substantially more than the general population, without being continually flooded by past memories. According cognitive inhibition dependency hypothesis, inhibitory processes modulate memory...
Abstract Purpose The discussion on the degree of similarity and continuity between more neutral memories genuine traumatic lies at core (at times too heated) debate possibility having declarative for personal experiences. In this paper, we aim taking a middle ground in debate, by examining, albeit very briefly, clinical, neurological behavioural data from hopefully objective point view. Method discussing memories, first necessary step is to clarify concept trauma, its use consequences...
The past decade has seen an increase in aspergillosis humans and animals due to Aspergillus viridinutans species complex members. Azole resistance is common these infections, carrying a poor prognosis. cyp51A gene mutations are the main cause of acquired azole fumigatus This study aimed determine if azole-resistant phenotype A. members associated with or extrolite profiles. clinical environmental isolates was amplified using novel primers, antifungal susceptibility tested Clinical Laboratory...
Invasive fungal infections (IFI) due to species in Aspergillus section Fumigati (ASF), including the viridinutans complex (AVSC), are increasingly reported humans and cats. The risk of exposure these medically important fungi Australia is unknown. Air soil was sampled from domiciles pet cats diagnosed with IFI a nature reserve Frankston, Victoria, where sensu stricto discovered 1954. Of 104 ASF isolated, 61% were A. fumigatus stricto, 9% AVSC (A. felis-clade frankstonensis sp. nov.) 30%...
Aspergillosis is a major cause of severe respiratory disease in birds. The prevalence cryptic section Fumigati and other non-Aspergillus fumigatus species as causative agents unknown. Species identity was determined 30 isolates from affected birds zoos, pet poultry by PCR the ITS1-5.8S-ITS2 partial β-tubulin genes. most prevalent isolate A. sens. str. 87% (26) cases. Other Aspergillus were identified 13% (4) cases, including restrictus (1), flavus (2), nidulans-clade (1). This first report...
Disseminated scedosporiosis is rare in dogs and usually reported German Shepherds with suspected heritable immunodeficiency. This the first report of disseminated due to Scedosporium prolificans a Labrador retriever dog that was receiving immunosuppressive drug therapy for treatment immune-mediated haemolytic anaemia. Despite cessation medications an initial response aggressive voriconazole terbinafine developed progressive disease neurological signs necessitating euthanasia six months from...
A 3.5 year-old cat was admitted to the University of Melbourne Veterinary Teaching Hospital for chronic vomiting. Abdominal ultrasonography revealed a focal, circumferential thickening wall duodenum extending from pylorus aborally 3 cm, and an enlarged gastric lymph node. Cytology fine-needle aspirates intestinal mass node eosinophilic inflammatory infiltrate numerous extracellular septate acute angle branching fungal-type hyphae. Occasional hyphae had globose terminal ends, as well round...
Abstract A 2‐year‐old male desexed Ragdoll cat with a 1‐year history of sneezing and nasal discharge presented large subcutaneous cervical mass, identified as the right medial retropharyngeal lymph node on computed tomography (CT). orbital destructive sino‐nasal cavity disease multiple pulmonary nodules were also identified. Aspergillus felis was cultured from node. After treatment posaconazole liposomal amphotericin B enlargement mass resolved but left frontal sinus involvement lesions...
Case summary A 13-year-old, castrated male, British Shorthair cat presented for investigation of chronic, intermittent, bilateral epistaxis and stertor. CT revealed severe asymmetric intranasal involvement with extensive turbinate lysis, increased soft tissue attenuation lysis the sphenopalatine bone cribriform plate. On retroflexed pharyngoscopy, a plaque-like mass occluded choanae. Rostral rhinoscopic examination loss nasal turbinates, necrotic mucosal fungal plaques in left cavity. The...
Smartphones are a fundamental part of modern life and have resulted in vast increase photo-taking. How smartphone use can affect cognitive processes, including memory, is poorly understood, but research shows taking photographs result photo-taking-impairment effect. Across 3 laboratory experiments, we aimed to replicate the impairment effect shed light into underlying mechanisms by manipulating encoding type (intentional vs. incidental) recognition stimuli (zoomed-in complete paintings)....