- Reproductive Biology and Fertility
- Neuroinflammation and Neurodegeneration Mechanisms
- Alzheimer's disease research and treatments
- Neurogenesis and neuroplasticity mechanisms
- Dental Implant Techniques and Outcomes
- MicroRNA in disease regulation
- Machine Learning in Bioinformatics
- Dental Trauma and Treatments
- Traditional Chinese Medicine Analysis
- Neurological Disease Mechanisms and Treatments
- Andrographolide Research and Applications
- Radiation Therapy and Dosimetry
- Hypothalamic control of reproductive hormones
- Ovarian function and disorders
- Dental materials and restorations
Mersin Üniversitesi
2019-2024
Massachusetts Eye Research and Surgery Institute
2023-2024
Purpose: Atractylenolide III (ATR III) is known for its anti-inflammatory and neuroprotective activities. In this study, we aimed to investigate the effects of ATR on neuronal damage in temporal epileptic rats caused by kainic acid. Materials Methods: 16-week-old Wistar Albino were divided into three groups; control (C, n=8), acid (KA, III+ (KA+ATR, n=8). After 21 days injections acid, learning, memory behavior, anxiety, locomotor activity evaluated. Neuron morphologies hippocampus examined,...
Amaç: Bu çalışmanın amacı nörobiyoloji çalışmalarında sıkça kullanılmakta olan HT22 fare hipokampal hücre hattının nöronal farklılaşma modeli olarak kullanılabilirliğinin anlaşılması için standart bir farklandırma besiyerine farklı sürelerde verdiği apoptotik cevabın sınanmasıdır. 
 Gereç ve Yöntemler: hücrelerinin ekilmesi dışında kültüre edilmesi HG-DMEM ise B27+ katkılı NB+ medyumu kullanılmıştır. Kontrol grubu da dâhil olmak üzere toplam 9 grup edilmiştir. Deney sonunda AnnexinV/PI...
Abstract Understanding how the immune system associates with pathophysiological hippocampal neurobiology in neurodegenerative diseases is an emerging topic. Since cellular population of neurogenic niche extraordinarily diverse, there still a large gap our understanding interactions between cells and neurons under even normal conditions, setting aside disease conditions. To examine receive respond to factors from cells, we introduced conditioned cell culture media (CM) unstimulated,...
Background and Objectives: The gold standard for a successful prosthetic approach is the osseointegration of an implant. However, this integration can be problem in cases where implant needs to removed. Removing with minimal damage surrounding tissues important. Osteocytes cannot survive below −2 °C, but epithelial cells, fibroblasts, other tissue cells can. Remodeling triggered by cryotherapy at temperatures that specifically affect osteocyte necrosis. In study, we aimed develop method...