Lifeng Hang

ORCID: 0000-0003-3228-2375
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About
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Research Areas
  • Nanoplatforms for cancer theranostics
  • Advanced battery technologies research
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Advanced biosensing and bioanalysis techniques
  • Advanced Nanomaterials in Catalysis
  • Electrocatalysts for Energy Conversion
  • Electrochemical sensors and biosensors
  • Supercapacitor Materials and Fabrication
  • Copper-based nanomaterials and applications
  • Nanoparticle-Based Drug Delivery
  • Photodynamic Therapy Research Studies
  • Advanced Photocatalysis Techniques
  • Quantum Dots Synthesis And Properties
  • Luminescence and Fluorescent Materials
  • Analytical Chemistry and Sensors
  • Advancements in Battery Materials
  • Photoacoustic and Ultrasonic Imaging
  • Electrochemical Analysis and Applications
  • Nanocluster Synthesis and Applications
  • Biosensors and Analytical Detection
  • Immunotherapy and Immune Responses
  • Pharmacological Effects and Assays
  • Cancer, Hypoxia, and Metabolism
  • Covalent Organic Framework Applications
  • Plasmonic and Surface Plasmon Research

Guangdong Provincial People's Hospital
2019-2025

Jinan University
2023-2025

University of Science and Technology of China
2014-2020

Institute of Solid State Physics
1994-2020

Chinese Academy of Sciences
2014-2020

Southern Medical University
2019-2020

Hefei National Center for Physical Sciences at Nanoscale
2019

Microscale (United States)
2019

Innate Pharma (France)
2019

Shenzhen University
2018-2019

Mo doped Ni<sub>2</sub>P nanowire arrays were prepared with enhanced activity toward the hydrogen evolution reaction at all pH values.

10.1039/c7nr03515b article EN Nanoscale 2017-01-01

Periodic porous alloyed Au-Ag nanosphere (NS) arrays with different periodic lengths and tunable composition ratios were prepared on Si substrates a large scale (∼cm2) using stepwise metal deposition-annealing subsequent chemical corrosion from monolayer of colloidal polystyrene (PS) microspheres as the initial template. The NSs possessed high porosity bicontinuous morphology composed hierarchically interconnected ligaments, which obtained an optimized dealloying process in nitric acid....

10.1021/acsami.7b17461 article EN ACS Applied Materials & Interfaces 2018-02-26

Abstract Infections caused by drug‐resistant bacteria represent a major contributor to high mortality rates, underscoring the urgent need for effective non‐antibiotic drugs and alternative therapies. Antimicrobial photodynamic therapy (aPDT) emerges as an innovative treatment due its minimal drug resistance. Herein, series of Nile Red derivatives is synthesized donor engineering strategy. Notably, NTPA featuring triphenylamine (TPA) electron‐donating group, exhibited highest production...

10.1002/adfm.202421072 article EN Advanced Functional Materials 2025-01-24

Hierarchical hetero-Ni<sub>3</sub>Se<sub>4</sub>@NiFe LDH micro/nanosheets were prepared by coupling NiFe nanosheets with Ni<sub>3</sub>Se<sub>4</sub> micro-sized sheets, and could be used as bifunctional electrocatalysts excellent activity durability for overall water splitting.

10.1039/c9nh00177h article EN Nanoscale Horizons 2019-01-01

nMOFs embellished with an AuNP nanozyme have great potential to generate O<sub>2</sub> for overcoming the tumor hypoxic microenvironment photodynamic therapy.

10.1039/c9bm00333a article EN Biomaterials Science 2019-01-01

The self-assembly of hydrophobic organic phototherapeutic agents (OPTAs) with expansive planar structures into nanoparticles (NPs) represents a pivotal strategy to bolster their biocompatibility. However, the tight molecular packing within these NPs significantly influences generation reactive oxygen species (ROS) and photothermal conversion efficiency (PCE), posing substantial hurdle elevating efficacy photodynamic therapy (PDT) (PTT) for such NPs. In this article, three OPTAs by donor...

10.1002/smll.202409196 article EN Small 2025-01-02

Sonodynamic therapy (SDT) is a noninvasive approach to tumor treatment, with ongoing efforts being focused on developing highly effective sonosensitizers low toxicity. Herein, liquid-phase stripping technique was introduced as simple reflux method for synthesizing ultrasmall Mn-PCN-224 nanodots (MM NDs). Compared PCN-224 nanodots, the synthesized MM NDs, which function renal-clearable nanoagents, produced 2.42 times more reactive oxygen species (ROS) under identical ultrasound (US)...

10.1021/acsami.4c21982 article EN ACS Applied Materials & Interfaces 2025-02-11

C-Co/Co<sub>3</sub>O<sub>4</sub> hollow nanoparticles with a low overpotential and Tafel slope.

10.1039/c7ta02539d article EN Journal of Materials Chemistry A 2017-01-01

Tumor hypoxia, which is indispensable to tumor propagation and therapy resistance, has been one of the most important factors influencing clinical outcomes. To modulate hypoxia microenvironment, we herein developed reactive oxygen species (ROS)-sensitive arylboronic ester-based biomimetic nanocarriers co-encapsulated with a photosensitizer chlorin e6 (Ce6) hypoxia-activated prodrug tirapazamine (TPZp) for tumor-specific release synergistic photodynamic chemotherapy. In order bypass...

10.1039/c9bm00634f article EN Biomaterials Science 2019-01-01

Ni<sub>0.33</sub>Co<sub>0.67</sub>MoS<sub>4</sub> nanosheets on carbon fiber cloth were employed as a bifunctional electrocatalyst for overall water splitting.

10.1039/c8ta07773h article EN Journal of Materials Chemistry A 2018-01-01

Recently, the chemodynamic therapy (CDT) has been widely reported and applied to tumor therapy. However, only low level hydroxyl radicals (•OH) generated by endogenous hydrogen peroxide alone are insufficient kill cancer cells. To overcome therapeutic effect, this study reports a novel CDT based on Fenton catalyst Au@Prussian blue nanocubes (Au@PB NCs), subsequently encapsulated with doxorubicin (Dox). The in vitro vivo results indicate that Dox-Au@PB NCs can take synergistic effects...

10.1021/acsami.9b13470 article EN ACS Applied Materials & Interfaces 2019-10-02

Sonodynamic therapy (SDT) offers a remarkable non-invasive ultrasound (US) treatment by activating sonosensitizer and generating reactive oxygen species (ROS) to inhibit tumor growth. The development of multifunctional, biocompatible, highly effective sonosensitizers remains current priority for SDT. Herein, the first report that Mn(II) ions chelated Gd-TCPP (GMT) nanosheets (NSs) are synthesized via simple reflux method encapsulated with pluronic F-127 form novel (GMTF). GMTF NSs produce...

10.1002/smll.202306364 article EN Small 2023-11-23

Introduction: Photodynamic therapy (PDT) and photothermal (PTT) are widely used in the treatment of tumors. However, their application clinical tumors is limited by complexity irreversible hypoxia environment generated tumor tissues. To overcome this limitation, a nanoparticle composed indocyanine green (ICG) Fe-MOF-5 was developed. Methods: We prepared F-I@FM5 measured its morphology, particle size, stability. Its enzyme like ability optical effect verified. Then we MTT, staining flow...

10.3389/fbioe.2023.1156079 article EN cc-by Frontiers in Bioengineering and Biotechnology 2023-03-30

Abstract Hydrogels possess unique polymer networks that offer flexibility/stretchability, high ionic conductivity, and resistance to electrolyte leakage, making them suitable for deformable energy storage devices. Endowing the mechanical functionality of hydrogel electrolytes focus on either enhancing stretchability or toughness. However, toughness are generally a trade‐off stretchable gels intrinsically prone damage sensitive notches cracks. Here, regulating strategies hydrogel's properties...

10.1002/smll.202305557 article EN Small 2024-01-09

The addition of an NC layer enhances the structural stability and electronic conductivity FeSe 2 ; thus, @NC exhibits remarkable rate performance long cycling capability for SIBs.

10.1039/d4ta00097h article EN Journal of Materials Chemistry A 2024-01-01

High-quality Au@ZnO core–shell nanoparticle (NP) array films were easily and efficiently fabricated through an air/water interfacial self-assembly. These materials have remarkable visible light absorption capacity fascinating performance in photoelectrochemical (PEC) water splitting with a photocurrent density of ∼3.08 mA/cm2 at 0.4 V, which is superior to most ZnO-based photoelectrodes studies. Additionally, the interesting PEC could be effectively adjusted by altering thickness ZnO shell...

10.1021/acsami.7b09325 article EN ACS Applied Materials & Interfaces 2017-08-30

The sponge-like Au–Ag alloy nanocubes (NCs) showed excellent SERS performance derived from high-density “hotspots” in nanopores, sharp corners and edges, synergistic effect between Au Ag species.

10.1039/c7tc03855k article EN Journal of Materials Chemistry C 2017-01-01

This review article provides a comprehensive overview of the latest developments in visible-light-excited RTP CDs, which includes luminescence mechanisms, preparation strategies, property regulation, and potential applications.

10.1039/d4tc01670j article EN Journal of Materials Chemistry C 2024-01-01
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