A5064429093- Insect Resistance and Genetics
- Forest Insect Ecology and Management
- Insect and Pesticide Research
- Natural Antidiabetic Agents Studies
- Insect-Plant Interactions and Control
- Cancer therapeutics and mechanisms
- Ethnobotanical and Medicinal Plants Studies
- Insect symbiosis and bacterial influences
- Essential Oils and Antimicrobial Activity
- Insect Pest Control Strategies
- Entomopathogenic Microorganisms in Pest Control
- Insect and Arachnid Ecology and Behavior
- Plant-Microbe Interactions and Immunity
- Plant tissue culture and regeneration
- Phytochemicals and Antioxidant Activities
- Diverse Scientific Research Studies
- Epigenetics and DNA Methylation
- Fungal and yeast genetics research
- Plant and animal studies
- Synthesis and Biological Evaluation
- Phytochemistry and Bioactivity Studies
- Transgenic Plants and Applications
- Bioactive Compounds and Antitumor Agents
- Drug-Induced Hepatotoxicity and Protection
- Weed Control and Herbicide Applications
Czech University of Life Sciences Prague
2018-2025
Swedish University of Agricultural Sciences
2015-2024
Jahangirnagar University
2024
West Bengal University of Animal and Fishery Sciences
2024
Medical College and Hospital, Kolkata
2022-2023
Sharda University
2022
Nil Ratan Sircar Medical College and Hospital
2022
Bose Institute
2011-2021
Visva-Bharati University
2003-2020
Sickle Cell Institute Chhattisgarh, Raipur
2015-2020
Abstract Climate change has increased the susceptibility of forest ecosystems, resulting in escalated decline globally. As one largest biomasses Northern Hemisphere, Eurasian boreal forests are subjected to frequent drought, windthrow, and high-temperature disturbances. Over last century, bark beetle outbreaks have emerged as a major biotic threat these forests, extensive tree mortality. Despite implementing various management strategies mitigate populations reduce mortality, none been...
Saccharomyces cerevisiae a and alpha cells express the complementary cell surface glycoproteins a-agglutinin alpha-agglutinin, respectively, which interact with one another to promote cellular aggregation during mating. Treatment of S. reducing agents releases binding subunit a-agglutinin, has been purified characterized; little biochemical information on overall structure is available. To characterise function, we have used genetic approach clone an structural gene (AGAI). Mutants...
Mitochondria are the principal site for generation of cellular ATP by oxidative phosphorylation. F0F1-ATP synthase, a complex V electron transport chain, is an important constituent mitochondria-dependent signaling pathways involved in apoptosis. In present study, we have shown first time that 3,3′-diindolylmethane (DIM), DNA topoisomerase I poison, inhibits mitochondrial synthase <i>Leishmania donovani</i> and induces programmed cell death (PCD), which novel insight into mechanism protozoan...
We present the results for CAPRI Round 30, first joint CASP-CAPRI experiment, which brought together experts from protein structure prediction and protein-protein docking communities. The comprised 25 targets amongst those submitted CASP11 experiment of 2014. included mostly homodimers, a few homotetramers, two heterodimers, chains that could readily be modeled using templates Protein Data Bank. On average 24 groups 7 CASP predictions each target, 12 per target participated in scoring...
Deciphering the molecular mechanisms mediating chemical senses, taste, and smell has been of vital importance for understanding nature how insects interact with their environment. Several gene families are implicated in uptake, recognition, termination signaling, including binding proteins, chemosensory receptors degrading enzymes. The cotton leafworm, Spodoptera littoralis, is a phytophagous pest current focal species insect ecology neuroethology.We produced male female Illumina-based...
Pesticide resistance development is an example of rapid contemporary evolution that poses immense challenges for agriculture. It typically evolves due to the strong directional selection pesticide treatments exert on herbivorous arthropods. However, recent research suggests some species are more prone evolve than others their evolutionary history and standing genetic variation. Generalist might develop especially rapidly pre-adaptation handle a wide array plant allelochemicals. Moreover, has...
In a subline of Reuber H35 rat hepatoma cells that becomes quiescent under serum-deprived conditions, insulin acts as growth factor.When added to serumdeprived cells, physiologic concentrations stimulate DNA synthesis, demonstrating alone is capable inducing transition from Go/ GI into S phase.This response, which induced by nanomolar insulin, mediated directly through the receptor.Here we show coincident with this or serum induces dramatic increases in steady-state levels c-fos and c-myc...
We present an attractive new system for the specific and sensitive detection of malaria-causing Plasmodium parasites. The relies on isothermal conversion single DNA cleavage-ligation events catalyzed specifically by enzyme topoisomerase I to micrometer-sized products detectable at single-molecule level. Combined with a droplet microfluidics lab-on-a-chip platform, this design allowed sensitive, specific, quantitative all human-malaria-causing species in drops unprocessed blood limit less...
The calcium (Ca2+) signaling is a crucial event during plant-herbivore interaction, which involves transient change in cytosolic Ca2+ concentration, sensed by Ca2+-sensors, and the received message transduced to downstream target proteins leading appropriate defense response. Calmodulin-like (CMLs) are calcium-sensing plant-specific proteins. Although CMLs have been identified few plants, they remained uncharacterized leguminous crop plants. Therefore, wide-range analysis of soybean was...
The spotted bollworm Earias vittella (Lepidoptera: Nolidae) is a polyphagous pest with enormous economic significance, primarily affecting cotton and okra. However, the lack of gene sequence information on this has significant constraint molecular investigations formulation superior management strategies. An RNA-seq-based transcriptome study was conducted to alleviate such limitations, de novo assembly performed obtain transcript sequences pest. Reference identification across E....
Abstract The ubiquitious enzyme topoisomerase I can be targeted by drugs which turn these enzymes into cellular poisons and subsequently induce cell death. Drugs like staurosporine, do not target directly, also lead to stabilization of I–DNA cleavable complexes an indirect process reactive oxygen species (ROS) generation subsequent oxidative DNA damage. In this study, we show that betulinic acid, a catalytic inhibitor topoisomerases, inhibits the formation apoptotic in prostate cancer cells...