Jessica Chang

ORCID: 0000-0003-3239-7252
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About
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Research Areas
  • Pharmaceutical Economics and Policy
  • Biosimilars and Bioanalytical Methods
  • Healthcare Policy and Management
  • Health Systems, Economic Evaluations, Quality of Life
  • Inflammatory Bowel Disease
  • Statistical Methods and Inference
  • Diversity and Career in Medicine
  • Drug-Induced Ocular Toxicity
  • Psoriasis: Treatment and Pathogenesis
  • Quantum Dots Synthesis And Properties
  • Cerebral Venous Sinus Thrombosis
  • Global Health Care Issues
  • Artificial Intelligence in Healthcare and Education
  • Eosinophilic Esophagitis
  • Economic and Financial Impacts of Cancer
  • Stoma care and complications
  • Advanced Causal Inference Techniques
  • Moyamoya disease diagnosis and treatment
  • Analytical Methods in Pharmaceuticals
  • Surgical site infection prevention
  • Pharmacology and Obesity Treatment
  • Statistical Methods in Clinical Trials
  • COVID-19 Pandemic Impacts
  • Healthcare Systems and Technology
  • Hepatitis C virus research

American Health Care Association
2023-2024

University of Southern California
2023-2024

University of California, San Diego
2024

Southern California Eye Institute
2023-2024

Tufts University
2024

Jacksonville College
2024

Mayo Clinic in Florida
2024

WinnMed
2024

Texas Plastic Surgery
2023-2024

University of Minnesota
2019-2023

To evaluate the accuracy and bias of ophthalmologist recommendations made by three AI chatbots, namely ChatGPT 3.5 (OpenAI, San Francisco, CA, USA), Bing Chat (Microsoft Corp., Redmond, WA, Google Bard (Alphabet Inc., Mountain View, USA). This study analyzed chatbot for 20 most populous U.S. cities.Each returned 80 total when given prompt "Find me four good ophthalmologists in (city)." Characteristics physicians, including specialty, location, gender, practice type, fellowship, were...

10.7759/cureus.45911 article EN Cureus 2023-09-25

We present a robust scheme for preparation of semiconductor quantum dots (QDs) and cognate partners in conjugation ready format. Our approach is based on bis-aryl hydrazone bond formation mediated by aromatic aldehyde hydrazinonicotinate acetone (HyNic) activated peptide coated dots. demonstrate controlled antibody--QD bioconjugates specific targeting endogenous epidermal growth factor receptors breast cancer cells single QD tracking transmembrane proteins via an extracellular epitope. The...

10.1021/bc100593m article EN Bioconjugate Chemistry 2011-05-10

Almost two-thirds of the 153 million nonelderly people in United States who have health insurance through their employer are self-insured plans. In contrast to fully insured plans, employers using plans assume responsibility for employees' medical costs and therefore an incentive reduce prices care services. We compared common services with those Using Health Care Cost Institute's data set claims one-third US population employer-sponsored insurance, we found that unadjusted were higher most...

10.1377/hlthaff.2023.00257 article EN Health Affairs 2023-09-01

In 2015 the Food and Drug Administration approved filgrastim-sndz (Zarxio), first US biosimilar. Following rapid uptake, by March 2018 accounted for 47 percent of filgrastim administrations among commercially insured 42 Medicare Advantage beneficiaries. The initial cost difference between originator biosimilar was 31 in former population but negligible latter.

10.1377/hlthaff.2019.00253 article EN Health Affairs 2019-11-01

Purpose The purpose of this study is to assess the accuracy and bias in recommendations for oculoplastic surgeons from three artificial intelligence (AI) chatbot systems. Methods ChatGPT, Microsoft Bing Balanced, Google Bard were asked practicing 20 cities with highest population United States. Three prompts used: "can you help me find (an surgeon)/(a doctor who does eyelid lifts)/(an oculofacial plastic surgeon) (city)." Results A total 672 suggestions made between (oculoplastic surgeon;...

10.7759/cureus.57611 article EN Cureus 2024-04-04

Abstract As policymakers continue to grapple with rising health care costs and prices, understanding trends variations in inpatient prices among hospital characteristics is an important benchmark allow craft targeted policies. In this study, we provide descriptive on variation paid by commercial plans stratified using data from Health Care Cost Institute's employer-sponsored insured claims data. Our analyses found evidence of considerable price levels growth system affiliation profitability....

10.1093/haschl/qxae140 article EN cc-by Health Affairs Scholar 2024-10-29

Importance Previous studies have found that hospitals participating in the 340B Drug Pricing Program higher Medicare Part B spending and expansion into affluent neighborhoods. Less is known about association of participation with by commercial insurance, where reimbursements are than Medicare. Objective To use Affordable Care Act eligibility for to study between on outpatient-administered oncological drugs commercially insured patients. Design, Setting, Participants This cohort included a...

10.1001/jamahealthforum.2023.1485 article EN cc-by-nc-nd JAMA Health Forum 2023-06-23

This cross-sectional study compares unit prices and price growth in employer-sponsored insurance Medicare over 2016 through 2020 for physician-administered drugs with the highest use those spending.

10.1001/jamahealthforum.2022.5422 article EN cc-by-nc-nd JAMA Health Forum 2023-02-10

Background and objectives: It is commonly taught that thyroid eye disease (TED) causes enlargement of the extraocular muscles (EOMs) in following descending order: inferior rectus (IR), medial (MR), superior (SR), lateral (LR), oblique (SO) (IO). However, with recent literature challenging this notion, we aimed to compare EOM volumes our cohort TED patients. Methods: We conducted a retrospective, non-randomized case-control study. Twenty-eight orbits from 28 unique patients who had...

10.7759/cureus.63843 article EN Cureus 2024-07-04

Methods for a sequential test of dose-response effect in pre-clinical studies are investigated. The objective the procedure is to compare several dose groups with zero-dose control. testing conducted within closed family one-sided tests. procedures investigated based on monotonicity assumption. These strongly control familywise error rate while providing information about shape dose-responce relationship. Performance compared via Monte Carlo simulation study. We illustrae by application real...

10.1080/03610920008832525 article EN Communication in Statistics- Theory and Methods 2000-01-01

In this article, we used administrative claims data from the OptumLabs Data Warehouse and American Hospital Association Annual Survey to examine associations between hospital characteristics uptake of biosimilar granulocyte colony-stimulating factor treatments. We found that 340B-participating hospitals non–rural referral center (RRC) reported owning rural health clinics were less likely administer lower-cost biosimilars, whereas opposite was true for are RRCs. To our knowledge, study offers...

10.37765/ajmc.2023.89363 article EN The American Journal of Managed Care 2023-05-22

Background: Recent literature has found rapid uptake of short-acting filgrastim biosimilars but slower other biosimilars, such as infliximab, in both Medicare and privately insured enrollees. Objectives: To describe patient, provider, health plan characteristics associated with a switch to biosimilar among existing infliximab patients. Research Design: We constructed retrospective panel dataset patients undergoing active treatments the choice drug for each infusion. used mixed logit...

10.1097/mlr.0000000000001906 article EN Medical Care 2023-08-10

The first FDA-approved biosimilar was launched in 2015: filgrastim-sndz (Zarxio), a for the reference drug filgrastim (Neupogen). Filgrastim is granulocyte colony-stimulating factor used to prevent and treat neutropenia. In this study, we examined association between site of care cost across filgrastim, tbo-filgrastim (Granix; version approved as Europe new United States), administrations among commercially insured.Retrospective study using administrative claims data.We OptumLabs Data...

10.37765/ajmc.2021.88730 article EN The American Journal of Managed Care 2021-08-23

Aim: Missing data, particularly missing variables, can create serious analytic challenges in observational comparative effectiveness research studies. Statistical linkage of datasets is a potential method for incorporating variables. Prior studies have focused upon the bias introduced by imperfect linkage. Methods: This analysis uses case study hepatitis C patients to estimate net effect statistical on bias, also accounting reduction variable bias. Results: The results show that reduce while...

10.2217/cer.15.23 article EN Journal of Comparative Effectiveness Research 2015-09-01

AMERICAN SOCIETY OF PLASTIC SURGEONS & RECONSTRUCTIVE SURGERY PRS GLOBAL OPEN ASPS EDUCATION NETWORK

10.1097/01.prs.0000444980.14443.6e article EN Plastic & Reconstructive Surgery 2014-02-26

Abstract Introduction Total parathyroidectomy on patients with hyperparathyroidism traditionally required an inpatient hospital stay to monitor for postoperative hypocalcaemia. Our centre developed a safe protocol in 2015 which enables total parathyroidectomies be carried out as day-case procedure. This protocol, conjunction the renal physicians, involves giving patient oral alfacalcidol preoperatively 5 days and close monitoring of calcium levels postoperatively permit same day discharge....

10.1093/bjs/znad241.046 article EN British journal of surgery 2023-08-21
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