About
Contact & Profiles
A5080342873
Research Areas
- Telomeres, Telomerase, and Senescence
- Inflammasome and immune disorders
- Hippo pathway signaling and YAP/TAZ
- Cancer, Hypoxia, and Metabolism
- Autophagy in Disease and Therapy
- Metabolism, Diabetes, and Cancer
- Congenital heart defects research
- Histone Deacetylase Inhibitors Research
Seoul National University
2023-2025
10.1038/s42255-023-00747-5
article
EN
Nature Metabolism
2023-03-02
Dynamic changes in cell size are associated with development and pathological conditions, including aging. Although enlargement is a prominent morphological feature of cellular senescence, its functional implications unknown; moreover, how senescent cells maintain their state less understood. Here we show that an extensive remodeling actin cytoskeleton necessary for establishing senescence-associated pro-inflammatory secretory phenotype (SASP). This attributed to balancing act between the...
10.1038/s41467-025-56929-0
article
EN
cc-by-nc-nd
Nature Communications
2025-02-17
Coming Soon ...