A5100611403- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Hearing, Cochlea, Tinnitus, Genetics
- Shoulder Injury and Treatment
- Spinal Fractures and Fixation Techniques
- Medical Imaging and Analysis
- Hearing Loss and Rehabilitation
- Anesthesia and Pain Management
- Ear Surgery and Otitis Media
- Orthopedic Surgery and Rehabilitation
- Cervical and Thoracic Myelopathy
- Vestibular and auditory disorders
- Peripheral Nerve Disorders
- Stroke Rehabilitation and Recovery
- Carbon Nanotubes in Composites
- Sports injuries and prevention
- Spinal Hematomas and Complications
- Healthcare and Venom Research
- Graphene research and applications
- Plasma Diagnostics and Applications
- Semiconductor materials and devices
- Muscle activation and electromyography studies
- Cerebral Palsy and Movement Disorders
- Myofascial pain diagnosis and treatment
- Pain Mechanisms and Treatments
Korea University
2015-2025
Korea Advanced Institute of Science and Technology
2002-2025
Korea University Medical Center
2012-2024
Samsung (South Korea)
2007-2024
Bucheon University
2023-2024
Soonchunhyang University Hospital
2023-2024
Korea Institute of Science and Technology
2023-2024
Konkuk University
2009-2023
Soonchunhyang University
2015-2023
Pusan National University
2022-2023
Lumbar provocation discography is a controversial diagnostic test. Currently, there concern that the test has an unacceptably high false-positive rate.Systematic review and meta-analysis.To perform systematic of lumbar studies in asymptomatic subjects discs with meta-analysis specificity rate discography.A literature was conducted via PUBMED search. Studies were included/excluded according to modern practices. Study quality scored using Agency for Healthcare Research Quality (AHRQ)...
The purpose of this study was to document particulate size in commonly used corticosteroid preparations. Inadvertent injection corticosteroids into a vertebral or foraminal artery can cause brain and spinal cord embolic infarcts the particles could be directly related chance that clinically significant infarct would occur. One might assume with significantly smaller than red blood cells safer.The following four types preparations were various solutions evaluated under light microscopy:...
A cold cathode X-ray tube was fabricated using a carbon nanotube (CNT) field electron emitter made by free-standing CNT film which is composed of highly packed network. lot bundles with sharp tip are vertically aligned at the edge thin length 10 mm and thickness 7 μm. The presents an extremely high current density 152 A/cm2 (corresponding to 106.4 mA), beam transmittance 95.2% small focal spot size (FSS) 0.5 mm. In addition, also shows stable lifetime during 100 000 shots. High emission...
Dynamic changes in cell size are associated with development and pathological conditions, including aging. Although enlargement is a prominent morphological feature of cellular senescence, its functional implications unknown; moreover, how senescent cells maintain their state less understood. Here we show that an extensive remodeling actin cytoskeleton necessary for establishing senescence-associated pro-inflammatory secretory phenotype (SASP). This attributed to balancing act between the...
Glucagon-like peptide-1-(7-36) (GLP-1) is a hormone derived from the proglucagon molecule, which considered highly desirable antidiabetic agent mainly due to its unique glucose-dependent stimulation of insulin secretion profiles. However, development GLP-1-based pharmaceutical has severe limitation very short half-life in plasma, being primarily degraded by dipeptidyl peptidase IV (DPP-IV) enzyme. To overcome this limitation, article we propose novel and potent DPP-IV-resistant form...
Various TiO2-coated ZnO samples were prepared by the sol−gel method for use as anode active materials of Ni−Zn secondary batteries. At a low annealing temperature, added titanium does not react with host material, ZnO, but forms an independent TiO2 domain coating layer. High-temperature annealing, however, results in reaction forming ZnTiO3 and Zn2TiO4. Whereas suppresses dissolution Zn passive surface layer, performance is reduced due to difficulty transporting ions through thicker layer...
Objective: We report a case study on possible alterations in resting-state functional connectivity between the auditory network and non-auditory brain regions tinnitus patients. Design: Independent component analyses were performed to evaluate coherent spontaneous activity distributed networks. The scores right left networks measured. Direct comparison of patients controls was made using two-sample t-test. Study sample: Four (three male, one female; mean age 45 ± 3.92 years) with chronic...
Abstract Background Hereditary hearing loss is one of the most common heterogeneous disorders, and genetic variants that can cause have been identified in over sixty genes. Most these genes detected using classical methods, typically starting with linkage analysis large families hereditary loss. However, strategies are not well suited for mutation smaller who insufficient information. Methods Eighty known were selected simultaneously sequenced by targeted next-generation sequencing (NGS) 8...
Clinical outcomes after the implantation of allogenic human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) in osteoarthritic knees have been rarely reported. Our study aimed to investigate clinical patients who underwent hUCB-MSC implantation.In this case series (level evidence: 4), from January 2014 December 2015, 128 with full-thickness cartilage lesions (International Cartilage Repair Society grade 4 and Kellgren-Lawrence ≤3) were retrospectively evaluated a minimum...
: Diabetic foot stands out as one of the most consequential and devastating complications diabetes. Many factors, including VIPS (Vascular management, Infection Pressure relief, Source healing), influence prognosis treatment diabetic patients. There are many studies on VIPS, but relatively few "sources healing". Nutrients that affect wound healing known, objective data in patients insufficient. We hypothesized healing" would have effects healing. The purpose this study is to know affecting...
Abstract Adipose tissues serve as an energy reservoir and endocrine organ, yet the mechanisms that coordinate these functions remain elusive. Here, we show transcriptional coregulators, YAP TAZ, uncouple fat mass from leptin levels regulate adipocyte plasticity to maintain metabolic homeostasis. Activating YAP/TAZ signalling in adipocytes by deletion of upstream regulators Lats1 Lats2 results a profound reduction converting mature into delipidated progenitor-like cells, but does not cause...
Diffusion tensor imaging is a new in vivo tool not only for the assessment of white matter structural integrity but also diagnosis and disease conditions which disturb tissue coherence. In this study, we investigated auditory pathway patients sensorineural hearing loss by means fractional anisotropy water diffusion to see any subtle changes pathways resulting from loss. addition, study suggests that measured highly sensitive otherwise processes normally seen with conventional magnetic...
For lack of a criterion standard for lumbar discogenic pain, the validity discography cannot be determined directly. The false-positive rate discography, however, can inferred from prevalence positive responses in asymptomatic volunteers. Responses normal volunteers have been reported only three studies, and has "occasionally, zero, 10%." None these controlled both pressure injection intensity response.To determine to volunteers, response.Prospective, observational study, conducted private...
Abstract Reactive oxygen and nitrogen are produced by rheumatoid arthritis (RA) synovial tissue can potentially induce mutations in key genes. Normally, this process is prevented a DNA mismatch repair (MMR) system that maintains sequence fidelity during replication. Key members of the MMR include MutSα (hMSH2 hMSH6) MutSβ hMSH3). To provide evidence damage inflamed synovium, we analyzed tissues for microsatellite instability (MSI). MSI was examined PCR on genomic paired peripheral blood...
We sought an optimal medial branch block (MBB) cutoff value for both single and double MBB protocols that would best correlate with a positive outcome of neurotomy (MBN).We analyzed the percentage subjective pain relief following MBB, confirmed by numerical rating scale (NRS) in aggravating positions before 45 minutes after MBB. The overall was plotted against variables: degree relief, duration patient satisfaction activity level, no other doctor's visits, reduction medications use.Using...
In this paper, a face and hand gesture recognition system which can be applied to smart TV interaction is proposed. Human natural are the key component interact with system. The used in viewer authentication control of TV, for example, volume up/down, channel changing. Personalized service such as favorite channels recommendation or parental guidance provided using recognition. We show that detection rate about 99% 97% by DGIST database. Also, 98% at distance 1 meter, 1.5 2 respectively....
We have investigated the analogue memory characteristics of an oxide-based resistive-switching device under electrical pulse to mimic biological spike-timing-dependent plasticity synapse characteristics. As a synaptic device, TiN/Pr0.7Ca0.3MnO3-based exhibiting excellent was used control weight by applying various amplitudes and cycles. Furthermore, potentiation depression with same spikes can be achieved negative positive pulses, respectively. By adopting complementary...