A5102777341- Glycosylation and Glycoproteins Research
- Coastal and Marine Dynamics
- Carbohydrate Chemistry and Synthesis
- Ocean Waves and Remote Sensing
- Video Surveillance and Tracking Methods
- Effects and risks of endocrine disrupting chemicals
- Sphingolipid Metabolism and Signaling
- Engineering Applied Research
- Earthquake and Tsunami Effects
- Advanced Chemical Sensor Technologies
- Lubricants and Their Additives
- Galectins and Cancer Biology
- Advanced ceramic materials synthesis
- Immunotherapy and Immune Responses
- Cardiovascular Function and Risk Factors
- Dam Engineering and Safety
- Fluid Dynamics Simulations and Interactions
- Biodiesel Production and Applications
- Contemporary Sociological Theory and Practice
- Technology and Human Factors in Education and Health
- Tropical and Extratropical Cyclones Research
- Aeolian processes and effects
- Pain Management and Treatment
- Fire Detection and Safety Systems
- Polysaccharides and Plant Cell Walls
Gladstone Institutes
2025
Kansai Electric Power (Japan)
2020-2024
Kanagawa University
2024
Advanced Science, Technology & Management Research Institute of Kyoto
2016
University of Yamanashi
1989-2014
Takeda (Japan)
2014
Kitasato University
2000-2013
Kagoshima University
1978-2011
Nagaoka University of Technology
1998-2009
Nagaoka University
1996-2009
Neuronal and glial cells organizing the central nervous system are generated from common neural precursor present in neuroepithelium during development. We tried to clarify functions of a cell surface microdomain, lipid raft, neuroepithelial (NECs). NECs suggested adhere fibronectin substratum dependently on integrin molecules. found that β1 integrin, component receptors, was distributed rafts. Methyl‐β‐cyclodextrin (MBCD), an inhibitor raft formation, inhibited integrin‐fibronectin...
Retrons are bacterial immune systems that protect a population against phages by killing infected hosts. typically comprise reverse transcriptase, template noncoding RNA is partially transcribed into RT-DNA, and toxic effector. The RNA, RT-DNA complex sequester the effector until triggered phage infection, at which point toxin released to induce cell death. Due their ability produce single-stranded DNA in vivo, retrons have also been engineered donor templates for genome editing both...
Abstract Neuronal and glial cells organizing the central nervous system (CNS) are generated from common neural precursor (NPCs) during development. However, expression of cell‐surface glycoconjugates that crucial for determining properties biological function these at different stages development has not been clearly defined. In this study, we investigated several stage‐specific glycoconjugate antigens, including b‐series gangliosides GD3, 9‐O‐acetyl GT1b GQ1b, embryonic antigen‐1 (SSEA‐1)...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA Model Structure of Zao Zhuang Bituminous CoalKazuo Nakamura, Toshimasa Takanohashi, Masashi Iino, Haruo Kumagai, Masaaki Sato, Susumu Yokoyama, and Yuzo SanadaCite this: Energy Fuels 1995, 9, 6, 1003–1010Publication Date (Print):November 1, 1995Publication History Published online1 May 2002Published inissue 1 November 1995https://pubs.acs.org/doi/10.1021/ef00054a011https://doi.org/10.1021/ef00054a011research-articleACS PublicationsRequest reuse...
It has been believed that the climate of East Africa is basically controlled by two “monsoons” which are prevalent over region. But, in addition, frequent appearances westerlies and their rain bringing character have long known empirically. The hitherto reports, however, contain some contradictory remarks regarding season appearance, spatial distribution, origin association with weather. author attempted to make a full use all available data meteorological observations investigate time...
We studied a patient with hyperglycemia who developed choreic involuntary movements in the right extremities using single photon emission computed tomography (SPECT) 123I-N-isopropyl-p-iodoamphetamine. SPECT revealed an increased blood flow left striatum and thalamus. Through control of glucose administration haloperidol, hemichorea was resolved, thalamus disappeared. These findings suggest that flow, which probably indicates neuron activity thalamus, is underlying pathophysiological state...
A novel trisialoganglioside has been isolated from dogfish (Squalus acanthias) brain. From the results of gas chromatography-mass spectrometric analysis methylated sugars, enzymatic hydrolysis, fast atom bombardment mass spectrometry, and proton nuclear magnetic resonance analysis, its structure was concluded to be (formula; see text) This is first report occurrence a ganglioside with 3 sialic acid residues separately linked gangliotetraosyl backbone.
Superfast transesterification of triolein (a biodiesel feedstock model) was achieved in the presence liquefied dimethyl ether using co-solvent effect and low viscosity. Furthermore, a method for higher ester yield, which methanol additionally introduced into reaction system immediately before beginning phase separation due to byproduct glycerin maintain homogeneous state, proposed. This led superfast high-yield with yield exceeding 96% at 3 min.
Rat small intestinal goblet cell mucins reacting with monoclonal antibody HCM31 increase significantly during regeneration from experimental mucosal damage and at the period of expulsion parasitic nematode, Nippostrongylus brasiliensis (N.b). The reduction in reactivity mucin upon neuraminidase treatment, suggested that recognizes sialylated oligosaccharide on mucin. HCM31-reactive sialomucins are therefore considered to play an important role physiological pathological changes...
A novel glycosphingolipid (SEGLx) has been isolated from the plerocercoids of a tapeworm, Spirometra erinacei. From results compositional analysis, methylation exoglycosidase hydrolysis, acid fast atom bombardment mass spectrometry, and proton nuclear magnetic resonance (NMR) its structure was concluded to be Galβ1-4Glc3|Fucα1β1-3Galβ1-1Ceramide This is first report with carbohydrate which characterized by i) occurrence penultimate glucose molecule attached reducing end galactose through...
The gangliosides in the brain of a cartilaginous fish, skate ( Bathyraja smirnovi ), have been isolated and characterized by means methylation analysis, antibody binding, enzymatic hydrolysis MALDI‐TOF MS. In addition to with known structures (GM2, fucosyl‐GM1, GD3, GD2, GT3 GT2), five polysialogangliosides were as having following structures. (1) IV 3 NeuAc, III 6 II NeuAc‐Gg 4 Cer; (2) NeuAc 2 , (3) ‐Gg (4) (5) Cer. These are ‘hybrid‐type’ which comprise combinations α‐series either a, b...
The higher temperature in the city was ascertained Nairobi, a of equatorial region, by analyzing climatological data and conducting measurements around city.Nairobi is with population 267, 000 (1962). It located at 1°17' S on East African Plateau gently sloping toward east. altitude ranges from 1, 800 meters west to 600 climate seems be modified locally presence forests wetter where average annual precipitation exceeds mm., extensive grasslands drier east trees are totally lacking about 840...
食用きのこ12株のフスマ固体培養を行い，その抽出液の凝乳活性を測定した結果，ヤマブシタケ（Hericium erinaceum) NBRC 100328に高い凝乳活性を見い出した．さらにMAFF7株のヤマブシタケについて凝乳活性を測定したところ，4株について凝乳活性が存在した．これら5株について低温殺菌牛乳を用いたカードの作製を行った結果，5株全てにおいてカードの作製が可能であった．全凝乳活性およびカード収量が高かった，Hericium erinaceum MAFF 435060，MAFF 430234，NBRC 100328をチーズ作製に適した株として選抜した．
Adult‐onset GM 2 gangliosidosis is very rare and only three autopsy cases have been reported up to now. We report herein an case of adult‐onset gangliosidosis. The patient developed slowly progressive motor neuron disease‐like symptoms after longstanding mood disorder cognitive dysfunction. He gait disturbance weakness lower limbs at age 52 years. Because muscle atrophy, he became bed‐ridden 65. At 68, died. His neurological findings presented slight disturbance, manic state, severe...
This glycosphingolipid was tentatively designated as GalSEGLx, in which the carbohydrate structure is characterized by an additional galactose molecule attached to reducing-end of SEGLx [Gal beta-4 (Fuc alpha-3) Glc beta-3 Gal beta Cer], previously determined us [Kawakami, Y., Nakamura, K., Kojima, H., Suzuki, M., Inagaki, F., A., Sonoki, S., Uchida, Murata, Y. & Tamai, (1993) J. Biochem. 114, 677-683], through a 1-6 linkage. The ceramide contained sphinganine and 4D-hydroxysphinganine about...