Yanlei Li

ORCID: 0000-0003-3246-5753
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About
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Research Areas
  • Cardiovascular Health and Disease Prevention
  • Advanced Surface Polishing Techniques
  • Blood Pressure and Hypertension Studies
  • Angiogenesis and VEGF in Cancer
  • Advanced biosensing and bioanalysis techniques
  • Viral Infections and Immunology Research
  • Indoor and Outdoor Localization Technologies
  • Cardiovascular and exercise physiology
  • Circular RNAs in diseases
  • Advanced Chemical Sensor Technologies
  • vaccines and immunoinformatics approaches
  • Hemodynamic Monitoring and Therapy
  • Advanced SAR Imaging Techniques
  • Bone and Joint Diseases
  • Radar Systems and Signal Processing
  • Cancer, Hypoxia, and Metabolism
  • RNA Interference and Gene Delivery
  • Additive Manufacturing Materials and Processes
  • Radio Wave Propagation Studies
  • Additive Manufacturing and 3D Printing Technologies
  • Infrared Thermography in Medicine
  • Advanced machining processes and optimization
  • Ferroelectric and Negative Capacitance Devices
  • Antenna Design and Optimization
  • Coronary Artery Anomalies

Shenzhen Second People's Hospital
2024-2025

Shantou University Medical College
2020-2025

Shantou University
2020-2025

Aerospace Information Research Institute
2020-2024

Chinese Academy of Sciences
2017-2024

Tianjin Medical University General Hospital
2024

Tianjin Medical University
2023-2024

Zhejiang Provincial People's Hospital
2023-2024

Bengbu Medical College
2024

Hangzhou Medical College
2023-2024

Severe fever with thrombocytopenia syndrome virus (SFTSV) is a novel tick-borne bunyavirus that recently emerged in East Asian countries. SFTS characterized by high fever, thrombocytopenia, leukopenia, multiorgan failure, and hemorrhage case fatality rates of 6.3% to 30%. Neither antivirals nor vaccines are available at present. We previously demonstrated neutralizing antibodies specific for SFTSV glycoprotein (Gn) played vital role the survival patients SFTS. Nanobodies from camels present...

10.1172/jci.insight.136855 article EN cc-by JCI Insight 2020-07-08

A skeletal pose estimation method, named RVRU-Pose, is proposed to estimate the of vulnerable road users based on distributed non-coherent mmWave radar. In view limitation that existing methods for are only applicable small scenes, this paper proposes a strategy combines radar intensity heatmaps and coordinate as input deep learning network. addition, we design multi-resolution data augmentation training method suitable achieve target remote multi-target application scenarios. Experimental...

10.3390/rs16040633 article EN cc-by Remote Sensing 2024-02-08

SARS-CoV-2 continues to be a major global health threat. In this study, we performed comprehensive meta-analysis on the epitopes of SARS-CoV-2, revealing its immunological landscape. Furthermore, using Shannon entropy for sequence conservation analysis and structural network-based methods identified candidate that are highly conserved evolutionarily constrained in other zoonotic coronaviruses. Finally, population coverage T cell was analyzed. The results highlighted regions within each...

10.3390/biology14010067 article EN cc-by Biology 2025-01-14

Intravenous thrombolysis (IVT) with recombinant tissue plasminogen activator (rt-PA) is the preferred treatment for acute ischemic stroke (AIS). Nevertheless, only approximately half of patients undergoing IVT experience positive outcomes. The objective study was to examine clinical characteristics AIS and identify predictors unfavorable outcomes at 3 months after IVT. This retrospective cohort comprised 3805 consecutive diagnosed who received Patients categorized as having a poor outcome...

10.1186/s12959-025-00704-0 article EN cc-by-nc-nd Thrombosis Journal 2025-03-10

To assess if active commuting with an electrically assisted bicycle (e-bike) during a 4-week period can induce increases in cardiorespiratory fitness measured as peak oxygen uptake (V[Combining Dot Above]O2peak) untrained, overweight individuals, and these changes are comparable those induced by conventional bicycle.Four-week randomized pilot study.Controlled laboratory.Thirty-two volunteers (28 men) participated. Seventeen {median age 37 years [interquartile range (IQR) 34, 45], median body...

10.1097/jsm.0000000000000438 article EN Clinical Journal of Sport Medicine 2017-07-19

Introduction Hypoxia is an important characteristic of solid tumors. However, spatial transcriptomics (ST) hypoxia-associated heterogeneity not clear. Methods This study integrated Spatial Transcriptomics with immunofluorescence to demonstrate their distribution in human claudin-low breast cancer MDA-MB-231 engraft. ST spots were clustered differentially expression genes. The data combined hypoxia-specific marker and angiogenesis marker-labeled serial sections indicate the hypoxia...

10.3389/fimmu.2022.1042835 article EN cc-by Frontiers in Immunology 2023-01-04

Percutaneous endoscopic transforaminal lumbar interbody fusion (PE-TLIF) has become one of the most popular minimally invasive surgeries today. However, issue hidden blood loss (HBL) in this surgery received little attention. This study aims to examine HBL PE-TLIF and effect tranexamic acid (TXA) on loss.

10.2147/tcrm.s462784 article EN cc-by-nc Therapeutics and Clinical Risk Management 2024-05-01

Introduction Osteoarthritis of the hip or knee has been reported to be linked an increased risk frailty. However, a definitive conclusion about whether osteoarthritis increases susceptibility frailty remains elusive. Material and methods The instrumental variables (IVs) used in this analysis were sourced from publicly available genome-wide association study (GWAS) datasets. We two-sample Mendelian randomization evaluate plausible causal nexus between Results included total 25...

10.5114/aoms/176741 article EN cc-by-nc-sa Archives of Medical Science 2024-04-25

Here we developed a composite scaffold of pearl/poly(lactic-co-glycolic acid) (pearl/PLGA) utilizing the low-temperature deposition manufacturing (LDM). LDM makes it possible to fabricate scaffolds with designed microstructure and macrostructure, while keeping bioactivity biomaterials by working at low temperature. Process optimization was carried out mixture pearl powder, PLGA 1,4-dioxane hierarchical structures, freeze-dried temperature −40 °C. Scaffolds square designated bone shape were...

10.1088/1758-5082/2/2/025002 article EN Biofabrication 2010-03-10

In response to the endoplasmic reticulum (ER) stress induced by herpes simplex virus type 1 (HSV-1) infection, host cells activate unfolded protein (UPR) reduce protein-folding burden in ER. The regulation of UPR upon HSV-1 infection is complex, and downstream effectors can be detrimental viral replication. Therefore, copes with create a beneficial environment for its has three branches, including kinase RNA (PKR)-like ER (PERK), inositol-requiring enzyme (IRE1), activated transcription...

10.3390/v9090235 article EN cc-by Viruses 2017-08-23

Background. Arterial stiffness can be measured using various non-invasive methods. It is not well established whether it necessary to standardize the time of day when performing these measurements. The aim present study examine effect daytime on arterial in individuals with and without heart disease. Methods. We investigated diurnal variation cardio-ankle vascular index (CAVI) carotid femoral pulse wave velocity (cfPWV). CAVI cfPWV were 70 participants (23 healthy young [HY], 22 elderly...

10.3109/00365513.2013.864787 article EN Scandinavian Journal of Clinical and Laboratory Investigation 2013-12-12

The chemical mechanical planarization (CMP) has been one of the major manufacturing process to provide global and local surface planarizations in integrated circuits (IC) fabrications. Defects such as micro-scratches generated during CMP can lead severe circuit failure, which affects yield. In present work, ethoxylated decylalchohol (EDA) was used dispersant agent prevent particles agglomeration reduce scratches. Firstly, effect EDA on particle size distribution (PSD) slurry investigated by...

10.1149/2.0101806jss article EN ECS Journal of Solid State Science and Technology 2018-01-01

Fast and flexible dense reconstruction has been extensively studied due to its wide application. Considering the efficiency of multi-robot systems, cooperative is gaining attention. Classic methods rely on inter-robot loop closures, which cannot work when there no common area between robots. Ultra-wideband sensors provide distance measurement can replace closures in systems. However, ranging-based schemes do not solve inconsistency reconstruction, caused by odometry drift. We propose a...

10.1109/lra.2023.3244721 article EN IEEE Robotics and Automation Letters 2023-02-16

A joint radar-communication (JRC) system utilizes the integrated transmit waveform and a single platform to perform radar communication functions simultaneously. Admittedly, multibeam design approach could assigned waveforms in different beams with aid of spatial temporal degrees freedom. However, high sidelobe level (SLL) beampattern reduces energy efficiency expands exposure probability. In this study, we propose novel spatial–temporal method based on beamforming algorithm form low SLL...

10.3390/rs15041167 article EN cc-by Remote Sensing 2023-02-20

With the development of integrated circuits (IC), ruthenium (Ru) has been selected as one most promising barrier metals for copper interconnects to replace traditional Ta/TaN bilayer. The present work investigates certain chemical aspects this strategy Ru-CMP by using guanidinium ions (Gnd+). And experiments are designed study Ru CMP in pH 9 colloidal silica-abrasive based slurry with an oxidizer (H2O2), Gnd+. Zeta potential, electrochemical and atomic force microscopy employed probe surface...

10.1149/2.0131708jss article EN ECS Journal of Solid State Science and Technology 2017-01-01

Resistance training has been shown to increase arterial stiffness. The purpose of the present study was examine and compare systemic stiffness responses acute lower body (LRT) upper (URT) resistance training. 20 healthy young men [median age: 26 years (interquartile range 23, 32)] underwent LRT, URT whole (WRT). Before immediately after, as well 20, 40 60 min after each session, we measured cardio-ankle vascular index (CAVI) brachial-ankle pulse wave velocity (baPWV) using VaSera VS-1500 N....

10.1055/s-0035-1549921 article EN International Journal of Sports Medicine 2015-07-24
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