A5108676104- Advancements in Transdermal Drug Delivery
- Monoclonal and Polyclonal Antibodies Research
- Drug Solubulity and Delivery Systems
- Proteins in Food Systems
- Protein purification and stability
- Surfactants and Colloidal Systems
- Advanced Drug Delivery Systems
- Ion Channels and Receptors
- Viral Infectious Diseases and Gene Expression in Insects
- Agricultural Practices and Plant Genetics
National Institute for Bioprocessing Research and Training
2019
The repertoire of complex proteins produced by the host cell during monoclonal antibody (mAb) production has generated a bottleneck in downstream bioprocessing. Low ppm levels (HCPs) must be achieved at purification process stage to generate an end product suitable for use humans. increased demand mAb drug products globally driven research focus on affordability platforms. This fuelled advancements manufacturing R&D deliver higher titres with better economics without sacrificing quality....
Objective: The aim of the study was to enhance transdermal flux and bioavailability, thereby reforming effectiveness drug delivery by synthesising characterising cilnidipine-loaded nanoemulsion-based gel. Methods: research conducted with meticulous planning execution. After preformulation studies, nanoemulsions were synthesised using probe sonication optimised a 2-factor central composite design. loaded in Carbopol 940 HPMC K4M gelling system. characterised for droplet size, zeta potential,...
Objective: This research aims to establish an efficient methodology for selecting nanoemulsion components synthesize eplerenone gel-based transdermal applications. Methods: The chemical compatibility study of was investigated by FTIR, DSC, and solubility in oils, surfactants, co-surfactants as the criteria choice. We used visual appraisal grading assess effectiveness emulsification. Various excipients were tested depending on solubility. final appearance, dispersibility, ease emulsification...
The flavour and aroma of chillies is because the presence capsaicinoids. Among capsaicinoids, 90% pungency due to capsaicin (8-methyl-N-vanillyl-trans-6-nonenamide) dihydrocapsaicin. From perspective food pharmaceutical industry, being used as an active component, there a need find quicker method estimating capsaicin. Also it imperative determine standardize fingerprint chilli extract different varieties, define pure sample containing by determining marker peak for capsaicin, using HPTLC....