A5059485267- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Total Knee Arthroplasty Outcomes
- Surgical site infection prevention
- Genetic Associations and Epidemiology
- Hip and Femur Fractures
- Osteoarthritis Treatment and Mechanisms
- Advanced materials and composites
- Hip disorders and treatments
- Cerebral Palsy and Movement Disorders
- Economics of Agriculture and Food Markets
- Infection Control and Ventilation
- Foot and Ankle Surgery
- Genetic and phenotypic traits in livestock
- Thermal Regulation in Medicine
- Peroxisome Proliferator-Activated Receptors
- Cancer-related molecular mechanisms research
- Orthopedic Surgery and Rehabilitation
- Musculoskeletal Disorders and Rehabilitation
- Infective Endocarditis Diagnosis and Management
- Antimicrobial Resistance in Staphylococcus
- Cardiac, Anesthesia and Surgical Outcomes
- Venous Thromboembolism Diagnosis and Management
- Knee injuries and reconstruction techniques
- Advanced X-ray and CT Imaging
Northumbria Healthcare NHS Foundation Trust
2011-2024
Wansbeck General Hospital
2009-2018
University Hospital Coventry
2018
University of Nottingham
2012
Background and purpose Enhanced Recovery (ER) is a well-established multidisciplinary strategy in lower limb arthroplasty was introduced our department May 2008. This retrospective study reviews short-term outcomes consecutive unselected series of 3,000 procedures (the “ER” group), compares them to numerically comparable cohort that had been operated on previously using traditional protocol “Trad” group).Methods Prospectively collected data surgical endpoints (length stay (LOS), return...
There have been no large comparative studies of the blood levels metal ions after implantation commercially available hip resurfacing devices which taken into account effects femoral size and inclination anteversion acetabular component. We present results in 90 patients with unilateral articular surface replacement (ASR) resurfacings (mean time to sampling 26 months) 70 Birmingham Hip Resurfacing (BHR) implants 47 months). The whole serum chromium (Cr) cobalt (Co) concentrations were...
We investigated the capacity of patient warming devices to disrupt ultra-clean airflow system. compared effects two technologies, forced-air and conductive fabric, on operating theatre ventilation during simulated hip replacement lumbar spinal procedures using a mannequin as patient. Infection data were reviewed determine whether joint infection rates associated with type device that was used. Neutral-buoyancy detergent bubbles released adjacent mannequin’s head at floor level assess...
Aims A fracture of the hip is most common serious orthopaedic injury, and surgical site infection (SSI) one significant complications, resulting in increased mortality, prolonged hospital stay often need for further surgery. Our aim was to determine whether high dose dual antibiotic impregnated bone cement decreases rate infection. Patients Methods quasi-randomised study 848 patients with an intracapsular conducted large teaching on two sites. All were treated a hemiarthroplasty. total 448...
Objectives Obesity as measured by body mass index (BMI) is one of the major risk factors for osteoarthritis. In addition, genetic overlap has been reported between osteoarthritis and normal adult height variation. We investigated whether this relationship due to a shared aetiology on genome-wide scale. Methods compared association summary statistics (effect size, p value) BMI from GIANT consortium study (GWAS) with arcOGEN GWAS. Significance was evaluated permutation. Replication highlighted...
Aims Surgical site infection (SSI) is a common complication of surgery with an incidence about 1% in the United Kingdom. Sutures can lead to development SSI, as micro-organisms colonize suture it implanted. Triclosan-coated sutures, being antimicrobical, were developed reduce rate SSI. Our aim was assess whether triclosan-coated sutures cause reduction SSIs following arthroplasty hip and knee. Patients Methods This two-arm, parallel, double-blinded study involved 2546 patients undergoing...
<h3>Objectives</h3> Osteoarthritis (OA) has a complex aetiology with strong genetic component. Genome-wide association studies implicate several nuclear genes in the aetiology, but major component of heritability yet to be defined at molecular level. Initial maternally inherited variants mitochondrial DNA (mtDNA) subgroups patients OA based on gender and specific joint involvement, these findings have not been replicated. <h3>Methods</h3> The authors studied 138 mtDNA genotyped two cohort...
Patient reported outcome measures (PROMs) were introduced in 2009 to allow patient perspectives potentially influence change and improvement. In collaboration with the national joint registry (NJR), PROMs data has been examined on a basis compare surgical factors total knee replacement (TKR). Initial results demonstrated there statistically significant differences Oxford Knee Score (OKS) when using different brands of implant. Preservation infrapatella fatpad (IFP) also shown improve...
Aims In metal-on-metal (MoM) hip arthroplasties and resurfacings, mechanically induced corrosion can lead to elevated serum metal ions, a local inflammatory response, formation of pseudotumours, ultimately requiring revision. The size diametral clearance anatomical (ADM) modular (MDM) dual-mobility polyethylene bearings match those Birmingham MoM components. If the acetabular component is satisfactorily positioned, well integrated into bone, has no surface damage, this presents opportunity...
187,000 hip and knee joint replacements are performed every year in the National Health Service (NHS). One of commonest complications is surgical site infection (SSI), this represents a significant burden terms patient morbidity, mortality cost to health services around world. The aim randomised controlled trial (RCT) determine if addition triclosan coated sutures standard regimen can reduce rate SSI after total replacement (TKR) (THR). 2400 patients due undergo or being recruited into...
INTRODUCTION The roles of non-medically trained practitioners within the NHS are expanding; they now being employed by many specialties, including surgery, to relieve pressures on healthcare teams. AIMS To investigate learning curve and competence an orthopaedic surgical care practitioner (SCP) in performing hip aspirations. METHODS Data were retrospectively collected 510 aspirations, which 360 completed a single SCP 150 surgeons before took over routine aspiration. aspirations separated...
Introduction: Metal-on-metal (MoM) total hip arthroplasty (THA) may cause adverse reactions to metal debris (ARMD). ARMD causing femoral vessel compression with serious complications has been described in case reports, but the rate of by is not known. This study aims investigate rate, and quantify severity, MoM hips lesions. Methods: Patients under surveillance for THA investigated MRI were studied. In patients confirmed ARMD, artery (FA) vein (FV) diameters measured at point maximal...
Abstract. Introduction: We undertook this study to know the sensitivity, specificity and post-test probabilities of hip aspiration when diagnosing periprosthetic infections. also examined “dry tap” (injection with saline aspiration) results volumes. Methods: This is a retrospective cohort patients aspirated for suspected joint infection between July 2012 October 2016. All aspirations were carried out by one trained surgical care practitioner (SCP). followed an aseptic technique fluoroscopic...
Periprosthetic joint infection is a serious complication of primary total hip replacement (THR) with significant associated morbidity. In acute infection, Debridement, Antibiotics and Implant Retention (DAIR) may be considered. Current national guidelines recommend DAIR should performed by “an experienced arthroplasty surgeon┕ but do not specify the need for this to revision surgeon. We investigated outcomes in our NHS Trust procedures non-revision surgeons. Infection registry data patient...
In metal-on-metal (MoM) hip replacements or resurfacings, mechanical induced corrosion can lead to a local inflammatory response, pseudo tumours and elevated serum metal ions, requiring revision surgery. The size diametral clearance of Anatomic (ADM) Modular (MDM) Dual Mobility bearings matches that certain MOM components. Presenting the opportunity for with exchange head ADM/MDM without removal acetabular component if it is well-fixed appropriately positioned. Between 2012 2020, across two...
Abstract Introduction National BOAST guidelines have been developed to coordinate and improve the standard of care for all patients with problems after knee replacement surgery. Since inception these we wanted assess impact on their pathways following discussions at our weekly revision MDT meetings. Methodology Trust casenotes programs, PACS software notes were evaluated over past 12 months (January 2022 December 2022) collect data problematic replacements. Current in-patients discussed...