Jiahui Zhao

ORCID: 0000-0003-3271-4334
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About
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Research Areas
  • Organoboron and organosilicon chemistry
  • Advanced battery technologies research
  • Electrocatalysts for Energy Conversion
  • Catalytic Cross-Coupling Reactions
  • Supercapacitor Materials and Fabrication
  • X-ray Diffraction in Crystallography
  • Crystallography and molecular interactions
  • Crystallization and Solubility Studies
  • Glioma Diagnosis and Treatment
  • Asymmetric Synthesis and Catalysis
  • Catalytic C–H Functionalization Methods
  • Ferroptosis and cancer prognosis
  • Fuel Cells and Related Materials
  • Heavy Metal Exposure and Toxicity
  • Plant Genetic and Mutation Studies
  • Proteins in Food Systems
  • Cancer Mechanisms and Therapy
  • Cell Image Analysis Techniques
  • Graphene and Nanomaterials Applications
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Protein Degradation and Inhibitors
  • Extracellular vesicles in disease
  • Circular RNAs in diseases
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Conducting polymers and applications

Anhui University
2023-2025

Liuzhou General Hospital
2025

Shandong University of Technology
2025

Shanghai University of Engineering Science
2023-2024

State Forestry and Grassland Administration
2024

Kunming University of Science and Technology
2024

Beijing Academy of Agricultural and Forestry Sciences
2024

Shenyang Agricultural University
2024

Henan University of Technology
2024

Jinan University
2021-2023

The precise fabrication and regulation of the stable catalysts with desired performance still challengeable for single atom catalysts. Here, Ru atoms different coordination environment in Ni3FeN lattice are synthesized studied as a typical case over alkaline methanol electrooxidation. buried subsurface (Ni3FeN-Ruburied) exhibits high selectivity Faradaic efficiency to formate conversion. Meanwhile, operando spectroscopies reveal that Ni3FeN-Ruburied an optimized adsorption reactants along...

10.1038/s41467-024-55615-x article EN cc-by-nc-nd Nature Communications 2025-01-02

Background The global burden of non-alcoholic steatohepatitis (NASH)-related liver cancer (NRLC) is increasing, making NASH the fastest-growing cause worldwide. This study presents a comprehensive analysis NRLC at global, regional, and national levels, further categorized by age, sex, sociodemographic index (SDI). Method Data on from Global Burden Disease, Injuries, Risk Factors (GBD) 2021 were downloaded levels. numbers age-standardized rates (ASRs) incidence, mortality, disability-adjusted...

10.3389/fnut.2025.1510563 article EN cc-by Frontiers in Nutrition 2025-01-27

The construction of acyclic, non-adjacent 1,3-stereogenic centers, prevalent motifs in drugs and bioactive molecules, has been a long-standing synthetic challenge due to acyclic nucleophiles being distant from the chiral environment. In this study, we successfully synthesized highly valuable 1,2-bis(boronic) esters featuring nonadjacent 1,3-stereocenters. Notably, reaction selectively produces migratory coupling products rather than alternative deborylative allylation or direct byproducts....

10.1002/anie.202318441 article EN Angewandte Chemie International Edition 2023-12-15

Adequate collateral circulation can remarkably improve patient prognoses for patients experiencing ischemic stroke. Hypoxic preconditioning enhances the regenerative properties of bone marrow mesenchymal stem cells (BMSCs). Rabep2 (RAB GTPase binding effector protein 2) is a key in remodeling. We investigated whether BMSCs and hypoxia-preconditioned (H-BMSCs) augment poststroke, particularly through regulation.BMSCs or H-BMSCs (1×106) were delivered intranasally mice with distal middle...

10.1161/atvbaha.122.318559 article EN Arteriosclerosis Thrombosis and Vascular Biology 2023-05-25

Abstract Background Drug-resistant bacterial infections in chronic wounds are a persistent issue, as they resistant to antibiotics and can cause excessive inflammation due generation of reactive oxygen species (ROS). An effective solution would be not only combat but also scavenge ROS relieve at the wound site. Scaffolds with antioxidant properties attractive for their ability ROS, there is medical demand developing enzyme-mimicking nanomaterials healing. Methods In this study, we fabricated...

10.1186/s40824-023-00429-z article EN cc-by Biomaterials Research 2023-02-09

Studies show tranexamic acid can reduce the risk of death and early neurological deterioration after intracranial haemorrhage. We aimed to assess whether reduces haematoma expansion improves outcome in intracerebral haemorrhage patients susceptible expansion.

10.1136/svn-2021-000942 article EN cc-by-nc Stroke and Vascular Neurology 2021-04-01

Comprehensive Summary Organoborons are commonly used building blocks for rapidly increasing molecular complexity. Although significant progress has been made in the selective functionalization of mono‐organoborons, site‐selective poly(organoborons) attracted substantial interest organic synthesis, pharmaceuticals, and agrochemicals due to presence multiple potential reaction sites. This review discusses various activation modes target C–B bond, with diverse transformations being achieved...

10.1002/cjoc.202400500 article EN Chinese Journal of Chemistry 2024-09-28

Calcium/calmodulin-dependent protein ID (CAMK1D) is widely expressed in many tissues and involved tumor cell growth. However, its role gliomas has not yet been elucidated. This study aimed to investigate the roles of CAMK1D proliferation, migration, invasion glioma. Through online datasets, Western blot, immunohistochemical analysis, glioma tissue significantly lower expression levels than normal brain (NB) tissues, was positively correlated with WHO classification. Kaplan-Meier survival...

10.3389/fonc.2022.845036 article EN cc-by Frontiers in Oncology 2022-04-13

Research exploring involvement of RNA N6-methyladenosine (m6A) in tomato (Solanum lycopersicum) seed germination remains limited. There is also a lack direct evidence supporting the interaction among germination, microgravity, and m6A modification. In this study, Micro-Tom tomatoes are used as experimental material to conduct genetic transformation, assay, modification levels identification experiments. During processes, level significantly increases under mutual influence various...

10.3390/horticulturae11030282 article EN cc-by Horticulturae 2025-03-05

Tomato (Solanum lycopersicum L.) is one of the major vegetable crops worldwide. Research on Janus kinase-signal transducer and activator transcription (JAK-STAT) signaling pathway in tomatoes other plant systems extremely limited. In this study, roles STAT, a crucial element JAK-STAT tomato seed germination low-temperature stress responses are examined, employing gene family analysis genetic transformation. The results indicate that S. genome contains only member STAT family, SlSTAT....

10.3390/ijms26073338 article EN International Journal of Molecular Sciences 2025-04-03

ABSTRACT Background The no‐reflow phenomenon in the ischemic brain following arterial recanalization leads to poor prognosis. Previous studies suggest that clinically proven NA‐1 drug, with disruption of PSD95 neuronal terminals alongside cerebral microvasculature, may inhibit pericytic contraction microvessels by reducing endothelin‐1 secretion. Methods A 1.5‐h tMCAO model using Balb/c mice was employed. In vivo two‐photon imaging and immunofluorescence staining were employed assess...

10.1111/cns.70409 article EN cc-by CNS Neuroscience & Therapeutics 2025-05-01

A novel palladium and norbornene catalyzed arene C–H activation method to synthesize various spirodihydroindenone derivatives is developed.

10.1039/c7qo00164a article EN Organic Chemistry Frontiers 2017-01-01

To uncover the internal mechanisms of various drought stress intensities affecting soluble sugar content in organs and its regulation by endogenous abscisic acid (ABA), we selected saplings

10.3390/biology13030194 article EN cc-by Biology 2024-03-19

Epidermal wax covers the surface of plants and plays an important role in regulating plant growth development stress resistance. However, there are few reports on synthesis lily petals. In this study, β-ketoacyl-CoA synthase 17 (LhKCS17), a key enzyme obtained from petals, was found to be located cytoplasm. Virus-induced gene silencing applied LhKCS17 flowers senesced earlier, cut showed premature aging decreased resistance water loss, petal crystals were sparse, total content reduced. When...

10.1016/j.postharvbio.2024.112902 article EN cc-by-nc Postharvest Biology and Technology 2024-03-27

Glioma is a common type of brain tumor with high incidence and mortality rates. Procollagen C-protease enhancer protein (PCOLCE) has been shown to regulate growth metastasis in several cancers. However, the role PCOLCE glioma unknown. This study aims assess association between prognosis glioma, investigated potential mechanisms.The prognostic value was determined using data from nine publicly available cohorts. We also relationship immune microenvironment predicted response immunotherapy...

10.1177/03946320221104548 article EN cc-by-nc International Journal of Immunopathology and Pharmacology 2022-04-01

The construction of silicon-stereogenic silanols via the Pd-catalyzed intermolecular C–H alkenylation with assistance a commercially available L-pyroglutamic acid has been realized for first time. Employing oxime ether as directing group, silanol derivatives could be readily prepared excellent enantioselectivities, featuring broad substrate scope and good functional group tolerance. Mechanistic studies indicate that stabilize Pd catalyst provide chiral induction. Preliminary computational...

10.26434/chemrxiv-2023-57wf2 preprint EN cc-by-nc 2023-08-17

Abstract The construction of acyclic, non‐adjacent 1,3‐stereogenic centers, prevalent motifs in drugs and bioactive molecules, has been a long‐standing synthetic challenge due to acyclic nucleophiles being distant from the chiral environment. In this study, we successfully synthesized highly valuable 1,2‐bis(boronic) esters featuring nonadjacent 1,3‐stereocenters. Notably, reaction selectively produces migratory coupling products rather than alternative deborylative allylation or direct...

10.1002/ange.202318441 article EN Angewandte Chemie 2023-12-15

Background: Branched-chain amino acid metabolism is involved in the pathogenesis of various liver diseases. In this study, we investigate potential role branched-chain metabolism-related genes hepatic ischemia reperfusion (HIRI). Methods: The gene Expression profiles HIRI were obtained from Gene Omnibu database. To determine differential expression between and normal tissues. Then, GO KEGG analyses performed, protein-protein interaction network was constructed. Next, random forest LASSO...

10.1101/2024.12.17.629007 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2024-12-20
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