A5063309913- Blood Pressure and Hypertension Studies
- Neurological Disorders and Treatments
- Cardiovascular Health and Disease Prevention
- Cancer, Lipids, and Metabolism
- Cancer Risks and Factors
- Pharmaceutical Practices and Patient Outcomes
- Menopause: Health Impacts and Treatments
- Healthcare Systems and Public Health
- Lipoproteins and Cardiovascular Health
- Eicosanoids and Hypertension Pharmacology
- Sodium Intake and Health
- Diet, Metabolism, and Disease
- Cardiac, Anesthesia and Surgical Outcomes
- Cerebrovascular and Carotid Artery Diseases
- Diabetes Treatment and Management
- Estrogen and related hormone effects
- Natural Products and Biological Research
- Apelin-related biomedical research
Volgograd State Medical University
2016-2020
Ministry of Health of the Russian Federation
2016-2018
Objective. To compare efficacy and safety of metformin monotherapy in combination with melatonin concerning the parameters endothelial function vascular elasticity, arterial hypertension (HTN), premature aging sleep status patients metabolic syndrome (MS). Design methods. We performed an open prospective, comparative, controlled, randomized trial 3 parallel groups. Altogether 238 MS (IDF, 2005), HTN 1–2 degrees (who reached target blood pressure (BP) current antihypertensive therapy)...
Aim . Evaluation of the ability fixed combination lisinopril, amlodipine and rosuvastatin (Equamer) in achievement additional angioprotection patients with systemic arterial hypertension (AH) high pulse wave velocity (PWV), regardless previous antihypertensive therapy (AHT). Material methods To open multicenter observational study 24 weeks duration, 60 included, taking double AHT during 6 months. All participants underwent ambulatory hour blood pressure (BP) monitoring, applanation tonometry...
Aim. To compare effectiveness of metformin monotherapy (Mf) and combination with slow release melatonine (MfM) from the perspective correction anthropometric, hemodynamical parameters, premature vascular ageing somnological status in patients metabolic syndrome (MS). Material methods. An open label prospective comparative study conducted, 3 parallel groups: 238 MS (IDF, 2005) having, at moment prescreening, sleep disorders (less than 19 points Questionnaire self evaluation), were randomized...
The aim of the study was to assess possibility fixed combination Lisinopril + amlodipine rozuvastatin improve arterial elesticity in patients with hypertension and high pulse wave velocity, despite previous diuretic-based antihypertensive therapy. Materials methods. In an open, observational duration 24 weeks included 60 on All participants underwent 24-hour blood pressure monitoring, applanation tonometry (augmentation index central pressure), velocity measurement, laboratory tests (lipid...
Metabolic syndrome is associated with the kidney damage, and microalbuminuria listed as one of key diagnostic criteria metabolic syndrome. In risk chronic diseases significantly increased. Moreover, damage also more severe in than patients without disorders, severity directly related to number components Chronic disease shown be all syndrome, including obesity, insulin resistance, hypertension. This article discusses issues drug nephroprotection (MS), uncontrolled arterial hypertension,...
Aim . Evaluation of the ability fixed combination perindopril and indapamide (Noliprel Bi Forte) to achieve additional angioprotection in patients with arterial hypertension already reached target blood pressure (BP) at previous antihypertension therapy losartan hydrochlorothiazide (HCT). Material methods. To open observational study, lasting 12 weeks, 25 included, those who had been taking losartan+HCT 100/12,5 mg. Results. During all underwent 24 hour BP monitoring, applanation tonometry...
Vessel Plus is an open acccess journal, which publishes articles related to vascular diseases, including acute respiratory distress syndrome, aneurysm, atherosclerosis, hypertension, stroke, peripheral or pulmonary etc.
Vascular aging is associated with increased arterial stiffness, vascular remodeling, and pulse wave propagation rate. This process can be accelerated by cumulative exposure to various factors that damage the wall: hypertension, hyperglycemia, dyslipidemia, smoking, etc. At present, there no convincing evidence of preferential effect certain components metabolic syndrome have greatest impact on acceleration in older patients. In this regard, a non-interactive study was conducted calculate age...
Aim. To compare effectiveness of non-drug therapy together with menopausal hormonal (MHT) — estradiol hemihydrate 1 mg/drospirenon 2 mg (Angeliq® Bayer Pharma AG (Germany)) related to normalization anthropometric and metabolic parameters, elasticity values vascular age in women syndrome (MS) postmenopause. Material methods. The open-label prospective comparative controlled randomized study parallel groups. Sixty female patients (mean 55,26±5,63 y.) MS (according IDF 2005 criteria) were...
Aim. To assess the possibility of monotherapy with perindopril after transferring from combination therapy losartan and hydrochlorothiazide respect to correction anthropometric, metabolic parameters, premature vascular aging elasticity in patients syndrome. Material methods. Held open prospective controlled study 50 syndrome (IDF, 2005), which reached BP<140/90 mm Hg during three months (50 mg) + (12.5 conversion 10 mg for 12 weeks. Patients were evaluated anthropometric levels adipokines,...
Aim. To assess the possibility of monotherapy with perindopril after transferring from combination therapy losartan and hydrochlorothiazide respect to correction anthropometric, metabolic parameters, premature vascular aging elasticity in patients syndrome. Material methods. Held open prospective controlled study 50 syndrome (IDF, 2005), which reached BP
Metabolic syndrome is associated with the kidney damage, and microalbuminuria listed as one of key diagnostic criteria metabolic syndrome. In risk chronic diseases significantly increased. Moreover, damage also more severe in than patients without disorders, severity directly related to number components Chronic disease shown be all syndrome, including obesity, insulin resistance, hypertension. This article discusses issues drug nephroprotection (MS), uncontrolled arterial hypertension,...