A5037163946- Blood Pressure and Hypertension Studies
- Cardiovascular Health and Disease Prevention
- Diabetes Treatment and Management
- Neurological Disorders and Treatments
- Healthcare Systems and Public Health
- Human Health and Disease
- Cardiovascular Function and Risk Factors
- Diabetes Management and Research
- Heart Failure Treatment and Management
- Eicosanoids and Hypertension Pharmacology
- Heart Rate Variability and Autonomic Control
- Helicobacter pylori-related gastroenterology studies
- Potassium and Related Disorders
- Asthma and respiratory diseases
- Hormonal Regulation and Hypertension
- Cardiac, Anesthesia and Surgical Outcomes
- Economic, Social, and Public Health Issues in Russia and Globally
- Renal function and acid-base balance
- Respiratory and Cough-Related Research
- Child and Adolescent Health
- Biomedical and Engineering Education
- Adolescent and Pediatric Healthcare
- Ultrasound and Hyperthermia Applications
- Magnesium in Health and Disease
- Apelin-related biomedical research
Volgograd State Medical University
2015-2024
Khakassian State University named after N.F. Katanov
2021-2022
Krasnoyarsk State Medical University
2014-2022
Ministry of Health of the Russian Federation
2018-2021
Volgograd Institute of Business
2018
Orenburg State Medical Academy
2016
Regional Public Health Care Institution "City Hospital No. 5, Barnaul"
2011
Aim. To assess the possibility of azilsartan medoxomil to achieve target blood pressure (BP) (less than 130/80 mm Hg), study angioprotective features and reduction adipokines levels inflammatory markers in patients with hypertension previous therapy other ARBs. Material methods . In open observational 24 weeks follow-up were included 60 (losartan or valsartan telmisartan). All underwent ambulatory BP monitoring, applanation tonometry (determination augmentation index central BP), measurement...
Objective. To compare efficacy and safety of metformin monotherapy in combination with melatonin concerning the parameters endothelial function vascular elasticity, arterial hypertension (HTN), premature aging sleep status patients metabolic syndrome (MS). Design methods. We performed an open prospective, comparative, controlled, randomized trial 3 parallel groups. Altogether 238 MS (IDF, 2005), HTN 1–2 degrees (who reached target blood pressure (BP) current antihypertensive therapy)...
Aim . Evaluation of the ability fixed combination lisinopril, amlodipine and rosuvastatin (Equamer) in achievement additional angioprotection patients with systemic arterial hypertension (AH) high pulse wave velocity (PWV), regardless previous antihypertensive therapy (AHT). Material methods To open multicenter observational study 24 weeks duration, 60 included, taking double AHT during 6 months. All participants underwent ambulatory hour blood pressure (BP) monitoring, applanation tonometry...
Aim. To evaluate the economic efficiency of using dapagliflozin in patients with chronic heart failure a reduced left ventricular ejection fraction ≤40% NYHA II–IV Russian Federation Methods. Conducted cost-benefit analysis/cost-minimization analysis and budget impact analysis. The calculation costs was carried out global model adapted to health care system by cost indicators disease characteristics. Results. addition standard compared only will provide an additional 0.356 LYGs (life years...
Aim . To study the effect of various classes glucose-lowering agents (dipeptidyl peptidase-4 (DPP-4) and sodium-glucose cotransporter-2 (SGLT-2) inhibitors) on vascular stiffness in patients with type 2 diabetes (T2D) high cardiovascular risk. Material methods. The open-label, prospective 24-week included 120 T2D We evaluated modern medications, empagliflozin at a dose 25 mg/day (SGLT-2 inhibitor) sitagliptin 100 (DPP-4 inhibitor), elasticity, central hemodynamic laboratory parameters....
Aim . To evaluate the potential of a fixed-dose combination lisinopril+amlodipine+rosuvastatin (Equamer®) in achieving additional vascular protection patients with hypertension and high pulse wave velocity (PWV) after severe very coronavirus disease 2019 (COVID-19), complicated by bilateral multisegmental viral pneumonia, use biological therapy, who had not previously received antihypertensive therapy. Material methods This 12-week open-label observational study included 30 or without The...
Aim. To present data from the AURA Registry (real-world registry on AlbUminuRia detection rate among patients with previously undiAgnosed chronic kidney disease). It is important to perform population studies both study occurrence of markers (albuminuria (AU), decreased glomerular filtration (GFR)) and prevalence disease (CKD), which will provide information actual CKD related in territories included research centers. Material methods . The article presents first registry. Recruitment was...
To evaluate the clinical and economic effectiveness of dapagliflozin in patients with chronic heart failure (CHF) reduced left ventricular ejection fraction (HFrEF) Russian Federation various subgroups standard therapy for CHF.
Prolactin is mainly secreted from the lactotroph cells in anterior pituitary, whose production controlled by dopamine. can be also produced extrapituitary tissues, such as mammary glands, placenta, uterus, prostate, brain where it may act an autocrine or paracrine factor. has some isoforms with different molecular weight, locations and biological functions. While not obligate lymphopoietic hormone, prolactin effects on immune system. Nevertheless, hematopoietic murine bone marrow thymus...
<h3>ЦЕЛЬ ИССЛЕДОВАНИЯ</h3> Изучить степень изменения сосудистой стенки, сосудистого возраста и метаболических параметров у полиморбидных пациентов, перенесших COVID-19. <h3>МАТЕРИАЛ И МЕТОДЫ</h3> В исследование включены 62 пациента с артериальной гипертензией, достигших целевых цифр уровня артериального давления (АД) на фоне двойной антигипертензивной терапии (АГТ) после перенесенного COVID-19 тяжелым крайне течением, которым проводили лабораторное параметров, оценку изменений показателей,...
Aim. To estimate the cost-effectiveness of dapagliflozin across range ejection fraction in patients with heart failure (HF) Russian Federation. Materials and methods. Cost-effectiveness model was developed for use as part standard therapy HF regardless is unknown. The calculation costs carried out a mathematical adapted to conditions healthcare system by using inputs patient population characteristics. Results. In model, yielded mean 0.209 additional life-years compared care 10 years...
Metabolic syndrome is associated with the kidney damage, and microalbuminuria listed as one of key diagnostic criteria metabolic syndrome. In risk chronic diseases significantly increased. Moreover, damage also more severe in than patients without disorders, severity directly related to number components Chronic disease shown be all syndrome, including obesity, insulin resistance, hypertension. This article discusses issues drug nephroprotection (MS), uncontrolled arterial hypertension,...
Purpose . To evaluate the economic and clinical results of aflibercept ranibizumab angiogenesis inhibitors in treat-and-extend regimen patients with “wet” form age-related macular degeneration (wAMD). Materials methods We analyzed cost minimization, impact on budget “missed opportunities” for treatment wAMD using intravitreal injections (IVI) compared to “treat-and-extend” (T & E). Costs were calculated regard system compulsory health insurance. calculate number IVI, network...
Diuretics are ones of the most popular classes antihypertensive remedies. They characterized by low cost, high efficiency, and a good acceptability. Therefore purpose research was to study an assortment diuretics develop merchandise inventory pharmacy organization improve quality population drug supply. During we used methods system, economic statistic analysis, questioning, content-analysis ABCanalysis. The resulted on three groups diuretic remedies depending specific density in general...
Aim. To evaluate the clinical and economic efficiency of use dapagliflozin in patients with chronic kidney disease (CKD) stages 24 Russian Federation.
 Materials methods. Cost-effectiveness (utility) analysis has been carried out. Mathematical model developed, adapted to healthcare system Federation by using cost characteristics inputs. Life years (LYG) quality-adjusted life (QALY) were used as criteria. Only direct medical costs taken into account. was out short-term (3 years)...
Aim . Evaluation of the ability fixed combination perindopril and indapamide (Noliprel Bi Forte) to achieve additional angioprotection in patients with arterial hypertension already reached target blood pressure (BP) at previous antihypertension therapy losartan hydrochlorothiazide (HCT). Material methods. To open observational study, lasting 12 weeks, 25 included, those who had been taking losartan+HCT 100/12,5 mg. Results. During all underwent 24 hour BP monitoring, applanation tonometry...
The study objective was to evaluate the ability of fixed combination (FC) perindopril + indapamide (P+I) reduce insulin resistance and low intensive noninfectious inflammation as well improve arterial elasticity in patients with hypertension, obesity prediabetes on previous successful antihypertensive therapy losartan hydrochlorothiazide (L+HTZ) 100/12.5 mg. A 12-week open-label included 50 (age 54.8 ± 6.6 years, body mass index (BMI) 32.5 3.2 kg/m2). All underwent a 24-hour ambulatory blood...
Vessel Plus is an open acccess journal, which publishes articles related to vascular diseases, including acute respiratory distress syndrome, aneurysm, atherosclerosis, hypertension, stroke, peripheral or pulmonary etc.
Te purpose of the study is to assess economic consequences use various anti-VEGF drugs in patients with diabetic macular edema (DME). Materials and methods. cost–effectiveness analysis budget impact was conducted from payer perspective (health insurance system). Results. In accordance results RCT (Protocol T) aflibercept required a lower number intravitreal injections (IVI) laser coagulations for frst year it has tendency IVI second treatment that resulted costs therapy by 122,819 rubles (12.7...
Aim. To assess azilsartan medoxomil (AZM) in achieving the target blood pressure (BP) (<140/90 mm Hg), its angioprotective action patients with hypertension (HTN), as well contribution reducing levels of adipokines and inflammation markers switching from lisinopril or enalapril. Material methods. This open-label observational study lasting 24 weeks included 60 who had previously received monotherapy 20 mg/day enalapril mg/day, did not reach BP Hg). During study, all underwent 24-hour...