A5054233910- Healthcare Systems and Public Health
- Cardiac Health and Mental Health
- Human Health and Disease
- Cardiovascular Effects of Exercise
- Health, psychology, and well-being
- Neurological Disorders and Treatments
- Cardiovascular and exercise physiology
- Cardiac electrophysiology and arrhythmias
- Heart Failure Treatment and Management
- Physical Education and Training Studies
- Cardiovascular Function and Risk Factors
- Blood Pressure and Hypertension Studies
- Medical and Biological Sciences
- Schizophrenia research and treatment
- Migraine and Headache Studies
- Psychological Treatments and Assessments
- Mental Health and Psychiatry
- Pharmacological Effects and Toxicity Studies
- Neurotransmitter Receptor Influence on Behavior
- Biochemical Acid Research Studies
- Sports Performance and Training
- Nitric Oxide and Endothelin Effects
- Heart Rate Variability and Autonomic Control
- Cardiac Imaging and Diagnostics
- Mental Health Treatment and Access
Siberian State Medical University
2014-2024
Tomsk National Research Medical Center
2019-2020
Mental Health Research Institute
2019
Ministry of Health of the Russian Federation
2018
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Клинические рекомендацииКоморбидная патология в клинической практике. рекомендацииОбщероссийская общественная организация Ассоциация врачей общей практики (семейных врачей).Секция "Сочетанные патологии" Рабочая группа: академик РАН, профессор Р. Г. Оганов (Председатель) (Москва), И. Н. Денисов В. Симаненков* (Научный координатор) (Санкт-Петербург), Бакулин Бакулина Болдуева С. А. член-корр.РАН Барбараш О. (Кемерово), Гарганеева П. (Томск), Дощицин Л. Драпкина М. к. м.н.Дудинская Е. Котовская...
Antipsychotic-induced parkinsonism (AIP) is a form of secondary that most often develops with blockade dopaminergic receptors type D2. However, AIP can oc-cur not only while taking first-generation APs, but also new ones have wider receptor pro-file. There connection between the DRD3 gene and regulation motor activity in associa-tion genetic studies AIP; Aim : to study role single-nucleotide variant rs167771 gene, encoding D3 type, risk Caucasian patients schizophrenia spectrum disorders...
Antidepressants (ADs) include drugs of various pharmacological groups, which are mainly used for the treatment mental disorders (major depressive disorder, obsessive-compulsive social phobia, panic generalized anxiety post-traumatic stress disorder), chronic pain and addiction diseases. Chronic use ADs can lead to development cardiotoxic adverse drug reactions (ADRs). The most important AD-induced ADRs prolongation QT interval, ventricular tachycardia "pirouette" type (Torsades de Pointes -...
In the interests of practical healthcare, routine classifications should be modified as rarely possible. At same time changes discarded only on sufficient grounds, for example, when there are no obvious advantages a new classification over existing ones or they can longer by introducing fundamental and amendments. this regard, evolution approaches to chronic heart failure (CHF) is prominent. It becomes particularly relevant due fact that currently experts Russian Society Cardiology (RSC)...
The members of the working group confirmed no conflict interest or financial support.
РЕЗЮМЕАктуальность.Нарушение метаболических процессов печени в результате воздействия алкогольной интоксикации снижает когнитивное функционирование и индуцирует когнитивные расстройства.С выраженностью расстройств связана тяжесть осложнений алкоголизма.У больных алкоголизмом с коморбидным поражением признаки когнитивных нарушений наблюдаются уже на ранних стадиях заболевания сопровождаются расстройствами внимания, памяти, восприятия, что дальнейшем зачастую приводит к социальной дезадаптации...
The usage of antipsychotics (APs) is the most robust and scientifically based approach in treatment schizophrenia spectrum disorders (SSDs). efficiency APs on a range target receptors central nervous system (CNS): serotoninergic, dopaminergic, adrenergic, histaminergic cholinergic. Metabolic are severe adverse drug reactions (ADRs) lead to cardiovascular diseases with high rate mortality patients SSDs. Neuropeptide Y receptor Y5 (NPY5R) known chain interaction for APs, agouti-related peptide...
Aim. To investigate on the electrocardiographic specifics of sportsmen at various stages training and competition processes according to sport type, intensity load type. Material methods. Totally, 136 male assessed. Qualified 116 persons (groups improvement mastery, age 22,07±4,10 y.o., in-sport time 5-15 years) were selected groups: I — wrestling (n=30), II ski racing, biathlon (n=27), III powerlifting (n=33), IV volleyball (n=26). Group V controls (n=20), 17,95±1,55 less than 3 years....
Inducible nitric oxide (NO) synthase (iNOS), encoded by the NOS2 gene, promotes generation of high levels NO to combat harmful environmental influences in a wide range cells. iNOS can cause adverse effects, such as falling blood pressure, if overexpressed. Thus, according some data, this enzyme is an important precursor arterial hypertension (AH) and tension-type headache (TTH), which are most common multifactorial diseases adults. The purpose study was investigate association rs2779249...
Important changes regarding the understanding of pathogenesis chronic heart failure (CHF) marked beginning millennium, and its first decade was called diastology. Even though numerous studies convincingly proved that deterioration left ventricular (LV) filling pressure often precedes impairment systolic function a number factors affect (especially at onset) mainly diastolic without changing conditions blood ejection, modern classifications approaches to CHF treatment are primarily based on...
Background: Nitric oxide (NO) is an important autocrine and paracrine signaling molecule that plays a crucial role in cardiovascular physiology pathology regulation. NO involved regulation of cerebral extra cranial blood flow arterial diameters. Reduced bioavailability the endothelium precursor for impaired vasodilation hypertension (AH). Furthermore, nociceptive processing. A NO-induced biphasic response with immediate delayed headache typical chronic tension-type headaches (TTH) humans....
The safety of the use psychotropic drugs, widely used in neurological and psychiatric practice, is an urgent problem personalized medicine. This narrative review demonstrated variability allelic frequencies low-functioning non-functional single nucleotide variants genes encoding key isoenzymes valproic acid P-oxidation liver across different ethnic/racial groups. sensitivity specificity pharmacogenetic testing panels for predicting rate metabolism by can be increased prioritizing inclusion...
Aim. To present data from the AURA Registry (real-world registry on AlbUminuRia detection rate among patients with previously undiAgnosed chronic kidney disease). It is important to perform population studies both study occurrence of markers (albuminuria (AU), decreased glomerular filtration (GFR)) and prevalence disease (CKD), which will provide information actual CKD related in territories included research centers. Material methods . The article presents first registry. Recruitment was...
Aim. To determine the prevalence and structure of risk factors (RF) for chronic noncommunicable diseases (CNCD) medical specialists in Tomsk Region depending on labor parameters, gender, residence specialty. Material methods . As part study, filled out questionnaires that included questions related to their activity, as well a questionnaire made up basis methodological recommendations "Monitoring practical healthcare". The was submitted electronic form posted website...
Кардиоваскулярная терапия и профилактика, 2015; 14(5) Влияние динамических статических физических нагрузок на показатели внутрисердечной гемодинамики физической работоспособности у квалифицированных спортсменов Гарганеева Н. П. 1 , Таминова И. Ф. 1,2 Тюкалова Л. Ворожцова 3 Буховец И