- Heart Failure Treatment and Management
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Healthcare Systems and Public Health
- COVID-19 and healthcare impacts
- Cardiovascular Function and Risk Factors
- Cardiac Health and Mental Health
- Atrial Fibrillation Management and Outcomes
- Acute Myocardial Infarction Research
- Human Health and Disease
- Blood Pressure and Hypertension Studies
- Cardiac pacing and defibrillation studies
- Chronic Disease Management Strategies
- Cardiac Imaging and Diagnostics
- Cardiovascular Health and Risk Factors
- Heart rate and cardiovascular health
- Liver Disease Diagnosis and Treatment
- Cardiac Structural Anomalies and Repair
- Heart Rate Variability and Autonomic Control
- Cardiovascular Disease and Adiposity
- SARS-CoV-2 and COVID-19 Research
- Cardiac Arrhythmias and Treatments
- Pneumonia and Respiratory Infections
- Renal and Vascular Pathologies
- Cardiac electrophysiology and arrhythmias
Privolzhsky Research Medical University
2016-2025
Aim To study the etiology and dynamics of prevalence mortality CHF; to evaluate treatment coverage such patients in a representative sample European part Russian Federation for 20-year period. Material methods A followed up 2002 through 2017 (n=19 276); population Nizhny Novgorod region examined 1998 (n=1922). Results During observation period since 2002, incidence major CHF symptoms (tachycardia, edema, shortness breath, weakness) tended decrease while cardiovascular diseases has...
Aim To study true prevalence of atrial fibrillation (AF) in a representative sample from the European part Russian Federation; to describe characteristics patients with AF; and provide frequency anticoagulant treatment.Material methods Cross-sectional data EPOCH epidemiological (2017) were used. Data collected 8 constituent entities size was 11 453 people. The included all respondents who had given their consent for participation older than 10 years. Statistical tests performed R system...
Background Mortality from chronic heart failure (CHF) remains high and entails serious demographic losses worldwide. The most vulnerable group is patients after acute decompensated HF (ADHF) who have a risk of unfavorable outcome.Aim To analyze risks all-cause death (ACD), cardiovascular (CVD), recurrent ADHF in CHF during two years following long-term follow-up with specialized medical care real-life clinical practice.Material methods study successively included 942 ADHF. 510 continued...
To perform a repeated epidemiological study of representative sample in the European part Russian Federation 2017 and to compare dynamics arterial hypertension (AH) prevalence with effectiveness blood pressure (BP) control population compared 1998, 2002, 2007.A was created 2002 re-examined 2007 2017. In pilot project performed for examining Nizhniy Novgorod region.During 19 years follow-up, AH increased from 35.5 43.3%. Te awareness treatment coverage reached 76.9 79.3%, respectively,...
Aim. To assess the effectiveness of vaccination against Omicron and Delta variants according to international registry "Dynamics Analysis Comorbidities in SARS-CoV-2 Survivors" (AKTIV-4). Material methods. The AKTIV-4 included men women over 18 years age with a diagnosis coronavirus disease 2019 (COVID-19) (oropharyngeal nasopharyngeal swabs, antibody titers, typical computed tomography performance), undergoing hospital treatment. A total 3543 patients from 25 medical centers 7 countries...
Relevance The number of patients with functional class III-IV chronic heart failure (CHF) characterized by frequent rehospitalization for acute decompensated HF (ADHF) has increased. Rehospitalizations significantly increase the cost patient management and burden on health care system.Objective To determine effect long-term follow-up at a specialized center treatment (Center Treatment Chronic Heart Failure, CTCHF) risk after ADHF.Materials Methods study successively included 942 CHF ADHF....
Aim . To analyze newly diagnosed diseases and features of the post-COVID course in patients after a coronavirus disease 2019 (COVID-19) within 12-month follow-up. Material methods A total 9364 consecutively hospitalized were included ACTIV registry. Enrollment began on June 29, 2020, was completed March 30, 2021, corresponding to first second waves pandemic. Demographic, clinical, laboratory data, computed tomography (CT) results, information about inhospital clinical complications COVID-19...
Aim. To analyze the lipid profile changes during acute phase of coronavirus disease 2019 (COVID-19) and within 12 months after discharge from hospital (post-Covid period) in comparison with patients before COVID-19. Material methods . The subanalysis registry was carried out as follows: clinical investigators each centers included AKTIV selected database who met three following criteria: (1) availability test no more than 60 days COVID-19; (2) period; (3) 6-12 hospital. Results In COVID-19,...
Aim. To evaluate the impact of community-acquired pneumonia (CAP) on short-term and long-term prognosis in patients hospitalized with signs chronic decompensated heart failure (CDHF). Subjects methods. A total 852 cases were admitted to therapy/cardiology hospital CDHF during a year. Results. Among CDHF, prevalence CAP was 16.5%. This indicator did not depend age patients. multisystem disorders, hypertension, different forms coronary disease, diabetes mellitus, obstructive pulmonary disease...
Aim To analyze the main reasons for impairment of life prognosis patients with chronic heart failure (CHF) in real clinical practice Russian Federation. Material and methods Representative samples population Nizhny Novgorod region (1998, n=1,922) European part Russia followed from 2002 through 2017 (n=19,276), as well randomly selected medical records outpatients under dispensary monitoring CHF 19 therapeutic preventive institutions three constituent entities Federation (n=177, 2022) were...
Aim. To study effects of gender differences in clinical and epidemiological factors on long-term prognosis for patients with acute decompensated heart failure (ADHF). Materials methods. A retrospective, observational analysis a sample (n=718) hospitalized signs ADHF subsequent collecting information about the endpoint (all-cause death) at four years. Results. Age was predictor unfavorable outcome both men women (RR, 1.04, 95% CI, 1.02–1.06, p<0.001 RR, 1.03–1.06, p<0.001). Presence lower...
To evaluate preparedness of physicians in real clinical practice to strive for stabilizing the course CHF by control and hemodynamic indexes both prevention admission decompensated following discharge from hospital.The study included 750 patients with any NYHA FC who were admitted emergency CHF. All followed up a year after hospital. Medical records inpatients (MRIP) outpatients (MROP) analyzed including determination symptoms administered doses medicines. Changes parameters during...
Aim. To determine time-related changes in prevalence, morbidity, and all-cause mortality of patients with CHF depending on the presence DM a representative sample Nizhny Novgorod Region. Materials methods. In 1998, Region was created, which included 1922 respondents. From 2000 through 2017, this evaluated three times. Patients were studied. Results. For 17 years, prevalence NYHA FC IV increased from 6.88 to 9.1% (р=0.04). Prevalence III-IV considerably 1.2% 4.8% (р<0.001). Morbidity 10.8...
Actuality. In the basic therapy of CHF, drugs that reduce pulse is one leading places. Target values heart rate with sinus rhythm are established. Tere still no consensus as to which ideal in patients CHF on background atrial fbrillation (AF). Te study prognosis and AF depending achieved relevant. Objective. To analyze overall mortality establish stratifcation risks death form AF, functional class presence tachycardia. Material methods. A prospective cohort was conducted a group who were...
Aim To present clinical characteristics of patients after hospitalization for acute decompensated heart failure (ADHF) and to analyze hemodynamic indexes compliance with the treatment at two years depending on conditions outpatient follow-up. Material methods The study included 942 chronic (CHF) older than 18 who had been hospitalized ADHF. Based patients’ decisions, groups were isolated: continued follow-up Center CHF (CCHF) (group 1, n=510) in multidisciplinary clinics (OMC) their place...
Aim . To study the prevalence of carbohydrate metabolism disorders in patients with heart failure (HF) hospitalized city HF center. Material and methods According to local registry, sequentially included 183 (99 men 84 women) Nizhny Novgorod center from September 1, 2019. The examination treatment were carried out accordance current clinical guidelines. In first 48 hours after hospitalization, concentration N-terminal pro-brain natriuretic peptide, soluble stimulating growth factor 2 (sST2),...
Aim To evaluate the risks of all-cause death (ACD), cardiovascular (CVD), from recurrent acute decompensated heart failure (ADHF), and a composite index CVD ADHF in patients with chronic (CHF) after first hospitalization for during long-term, five-year follow-up conditions specialized medical care real clinical practice. Material methods This prospective cohort observational study included 942 ADHF. Group 1 consisted 510 who continued outpatient at center treatment CHF (cCHF); group 2 432...
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Aim. To present data from the AURA Registry (real-world registry on AlbUminuRia detection rate among patients with previously undiAgnosed chronic kidney disease). It is important to perform population studies both study occurrence of markers (albuminuria (AU), decreased glomerular filtration (GFR)) and prevalence disease (CKD), which will provide information actual CKD related in territories included research centers. Material methods . The article presents first registry. Recruitment was...
Earlier studies have demonstrated a high prevalence of atrial fibrillation (AF) in patients with CHF. It was noticed that tachycardia and hypotension provoked risks for cardiovascular mortality. The presence arterial hypertension (AH) CHF also impairs life prognosis.To determine prognosis based on the control hemodynamic indexes titration pulse-slowing therapy real-life clinical practice.This prospective study one-year followup period included 580 after decompensated who were discharged from...