John J. Moore

ORCID: 0000-0003-3287-0513
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About
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Research Areas
  • Metal and Thin Film Mechanics
  • Diamond and Carbon-based Materials Research
  • Intermetallics and Advanced Alloy Properties
  • Advanced materials and composites
  • Hematopoietic Stem Cell Transplantation
  • Preterm Birth and Chorioamnionitis
  • Advanced ceramic materials synthesis
  • Neonatal Respiratory Health Research
  • Systemic Sclerosis and Related Diseases
  • Acute Lymphoblastic Leukemia research
  • Acute Myeloid Leukemia Research
  • MXene and MAX Phase Materials
  • Chronic Myeloid Leukemia Treatments
  • Pregnancy-related medical research
  • Reproductive System and Pregnancy
  • Boron and Carbon Nanomaterials Research
  • Pregnancy and preeclampsia studies
  • Aluminum Alloys Composites Properties
  • Polyomavirus and related diseases
  • Metal Alloys Wear and Properties
  • Semiconductor materials and devices
  • Multiple Sclerosis Research Studies
  • Energetic Materials and Combustion
  • Bone Tissue Engineering Materials
  • Metallurgical Processes and Thermodynamics

UNSW Sydney
2012-2024

St Vincent's Hospital Sydney
2015-2024

St Vincent's Health
2005-2024

St Vincent's Hospital
2006-2024

The Kinghorn Cancer Centre
2023-2024

St Vincent's Clinic
2018-2024

St Vincents Institute of Medical Research
2013-2024

University of South Alabama Medical Center
2023

Gold Coast Hospital
2023

Saint Vincent's Catholic Medical Center
1999-2021

10.1016/0079-6425(94)00011-5 article EN Progress in Materials Science 1995-01-01

Background Autologous hematopoietic stem cell transplantation has been used since 1996 for the treatment of severe autoimmune diseases refractory to approved therapies. We evaluated long-term outcomes these transplants and aimed identify potential prognostic factors.Design Methods In this observational study we analyzed all first autologous reported European Group Blood Marrow Transplantation (EBMT) registry between 1996–2007. The primary end-points analysis were overall survival,...

10.3324/haematol.2009.013458 article EN cc-by-nc Haematologica 2009-09-22

These updated EBMT guidelines review the clinical evidence, registry activity and mechanisms of action haematopoietic stem cell transplantation (HSCT) in multiple sclerosis (MS) other immune-mediated neurological diseases provide recommendations for patient selection, transplant technique, follow-up future development. The major focus is on autologous HSCT (aHSCT), used MS over two decades currently fastest growing indication this treatment Europe, with increasing evidence to support its use...

10.1038/s41409-019-0684-0 article EN cc-by Bone Marrow Transplantation 2019-09-26

Background Autologous haematopoietic stem cell transplantation (AHSCT) has been explored as a therapeutic intervention in multiple sclerosis (MS) over the last two decades; however, prospective clinical trials of most common myeloablative conditioning regimen, BEAM, are limited. Furthermore, patient selection, optimal chemotherapeutic regimen and immunological changes associated with disease response require ongoing exploration. We present outcomes, safety immune reconstitution (IR) patients...

10.1136/jnnp-2018-319446 article EN Journal of Neurology Neurosurgery & Psychiatry 2018-12-11

Abstract Objective Evidence from animal studies, case reports, and phase I studies suggests that hemopoietic stem cell transplantation (HSCT) can be effective in the treatment of rheumatoid arthritis (RA). It is unclear, however, if depletion T cells product infused after high‐dose chemotherapy beneficial prolonging responses by reducing number autoreactive cells. This pilot multicenter, randomized trial was undertaken to obtain feasibility data on whether CD34 selection (as a form...

10.1002/art.10495 article EN Arthritis & Rheumatism 2002-09-01

The mechanisms by which fetal membranes (FM) rupture during the birth process are unknown. We have recently reported that FM weaken, at least in part, because of a developmental extracellular matrix remodeling and apoptosis. now hypothesize cytokines normally increase amniotic fluid term induce collagen apoptosis with concomitant weakening. Full-thickness fragments were cultured (0-100 ng/ml) or without tumor necrosis factor (TNF) interleukin 1, beta (IL1B). Physical properties then examined...

10.1095/biolreprod.105.045328 article EN Biology of Reproduction 2005-09-08
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