A5007969577- Total Knee Arthroplasty Outcomes
- Blood transfusion and management
- Venous Thromboembolism Diagnosis and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Diabetes Treatment and Management
- Inflammatory mediators and NSAID effects
- Anesthesia and Pain Management
- Atrial Fibrillation Management and Outcomes
- Knee injuries and reconstruction techniques
- Shoulder Injury and Treatment
Kinan Hospital
2018-2020
Riso Kagaku (Japan)
2007
Background: Combined intraoperative intravenous and intra-articular tranexamic acid (TXA) is 1 of the most effective administration routes to decrease amount perioperative blood loss during total knee arthroplasty (TKA). However, additive effect postoperative TXA remains unclear. We hypothesized that repeated-dose would provide lower loss. Methods: performed a double-blinded, placebo-controlled trial involving patients undergoing primary TKA. A 100 who were managed with combined randomly...
This study was performed to determine whether periarticular injection in the early stage of total knee arthroplasty (TKA) could provide a better postoperative pain relief than late TKA. The hypothesis based on concept that analgesic intervention before onset noxious stimuli would be associated with less pain. A 105 participants were randomly assigned receive superficial just prior arthrotomy (early group) or after implanting prosthesis (late-stage patients undergoing unilateral TKA 1:1...
Intra-articular tranexamic acid (TXA) as an adjunct to intravenous TXA was reported decrease perioperative blood loss during unilateral total knee arthroplasty (TKA). However, there have been no randomized controlled trials comparing versus combined and intra-articular administration in patients undergoing simultaneous bilateral TKA.We randomly assigned 77 with 154 involved knees TKA the group (intra-articular placebo for each knee) or (1000 mg of 1:1 treatment allocation. In both groups,...
Although continuing antithrombotic therapy is desirable to prevent perioperative cardiovascular and cerebrovascular diseases, blood loss remains a concern in patients undergoing total knee arthroplasty. The purpose of this study was assess the impact chronic on major bleeding events.We classified 201 consecutive arthroplasty into 2 groups: (1) taking antiplatelet agents, vitamin K antagonists, and/or direct oral anticoagulants, referred as group (n = 32); (2) not receiving these no 169)....