Junxiu Liu

ORCID: 0000-0003-3303-0217
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About
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Research Areas
  • Obesity, Physical Activity, Diet
  • Nutritional Studies and Diet
  • Consumer Attitudes and Food Labeling
  • Food Security and Health in Diverse Populations
  • Cardiovascular Health and Risk Factors
  • Gestational Diabetes Research and Management
  • Global Public Health Policies and Epidemiology
  • Blood Pressure and Hypertension Studies
  • Birth, Development, and Health
  • Health disparities and outcomes
  • Physical Activity and Health
  • Trace Elements in Health
  • Coffee research and impacts
  • Diet and metabolism studies
  • Heavy Metal Exposure and Toxicity
  • Climate Change and Health Impacts
  • Endometrial and Cervical Cancer Treatments
  • Air Quality and Health Impacts
  • Cancer Immunotherapy and Biomarkers
  • Iron Metabolism and Disorders
  • Aluminum toxicity and tolerance in plants and animals
  • Cancer Cells and Metastasis
  • Vascular Tumors and Angiosarcomas
  • Sodium Intake and Health
  • Economic and Financial Impacts of Cancer

The First Affiliated Hospital, Sun Yat-sen University
2011-2025

Sun Yat-sen University
2013-2025

Icahn School of Medicine at Mount Sinai
2021-2024

Peking University
2013-2023

Peking University Third Hospital
2013-2023

Georgia Institute of Technology
2023

Tufts University
2017-2022

Ningxia Medical University
2022

Shenyang The Fourth Hospital of People
2022

The Fourth People's Hospital
2022

The American Heart Association, in conjunction with the National Institutes of Health, annually reports most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, weight) factors (cholesterol, blood pressure, glucose control) that contribute health. Statistical Update presents latest data on a range major clinical circulatory disease conditions (including congenital rhythm disorders,...

10.1161/cir.0000000000000950 article EN cc-by-nc-nd Circulation 2021-01-27

<h3>Importance</h3> Prior studies of dietary trends among US youth have evaluated major macronutrients or only a few foods used older data. <h3>Objective</h3> To characterize in diet quality youth. <h3>Design, Setting, and Participants</h3> Serial cross-sectional investigation using 24-hour recalls from aged 2 to 19 years 9 National Health Nutrition Examination Survey (NHANES) cycles (1999-2016). <h3>Exposures</h3> Calendar year population sociodemographic characteristics. <h3>Main Outcomes...

10.1001/jama.2020.0878 article EN JAMA 2020-03-24

BACKGROUND Risk of coronavirus disease 2019 (COVID-19) hospitalization is robustly linked to cardiometabolic health. We estimated the absolute and proportional COVID-19 hospitalizations in US adults attributable 4 major conditions, separately jointly, by race/ethnicity, age, sex. METHODS AND RESULTS used best available estimates independent associations conditions with a risk hospitalization; nationally representative data on from National Health Nutrition Examination Survey 2015 2018;...

10.1161/jaha.120.019259 article EN cc-by-nc-nd Journal of the American Heart Association 2021-02-25

<h3>Importance</h3> Unhealthful diet is a top contributor to chronic diseases in the United States. There are growing concerns about disparities among US adults, especially for those who participate Supplemental Nutrition Assistance Program (SNAP), largest federal food assistance program. It remains unclear how these may have changed over time. <h3>Objective</h3> To assess whether key groups and nutrients according participation eligibility SNAP persisted, improved, or worsened time adults....

10.1001/jamanetworkopen.2018.0237 article EN cc-by-nc-nd JAMA Network Open 2018-06-15

<h3>Importance</h3> Time trends and population disparities in nutritional quality of foods from major US sources, including grocery stores, restaurants, schools, worksites, other are not well established. <h3>Objective</h3> To investigate patterns diet by food sources among children adults overall sociodemographic subgroups. <h3>Design, Setting, Participants</h3> This serial, cross-sectional survey study included respondents 8 National Health Nutrition Examination Survey cycles (2003-2018)...

10.1001/jamanetworkopen.2021.5262 article EN cc-by-nc-nd JAMA Network Open 2021-04-12

Diet is an important risk factor for cancer that amenable to intervention. Estimating the burden associated with diet informs evidence-based priorities nutrition policies reduce in United States.

10.1093/jncics/pkz034 article EN cc-by JNCI Cancer Spectrum 2019-04-30

The Supplemental Nutrition Assistance Program (SNAP) provides approximately US$70 billion annually to support food purchases by low-income households, supporting 1 in 7 Americans. In the 2018 Farm Bill, potential SNAP revisions improve diets and health could include financial incentives, disincentives, or restrictions for certain foods. However, overall comparative impacts on outcomes costs are not established. We aimed estimate impact, program healthcare costs, cost-effectiveness of SNAP.We...

10.1371/journal.pmed.1002661 article EN cc-by PLoS Medicine 2018-10-02

Background Economic incentives through health insurance may promote healthier behaviors. Little is known about and economic impacts of incentivizing diet, a leading risk factor for diabetes cardiovascular disease (CVD), Medicare Medicaid. Methods findings A validated microsimulation model (CVD-PREDICT) estimated CVD cases prevented, quality-adjusted life years (QALYs), health-related costs (formal healthcare, informal lost-productivity costs), incremental cost-effectiveness ratios (ICERs)...

10.1371/journal.pmed.1002761 article EN cc-by PLoS Medicine 2019-03-19

Background Poor diet is a leading risk factor for cardiometabolic disease (CMD) in the United States, but its economic costs are unknown. We sought to estimate cost associated with suboptimal US. Methods and findings A validated microsimulation model (Cardiovascular Disease Policy Model Risk, Events, Detection, Interventions, Costs, Trends [CVD PREDICT]) was used annual cardiovascular (fatal nonfatal myocardial infarction, angina, stroke) type 2 diabetes intake of 10 food groups (fruits,...

10.1371/journal.pmed.1002981 article EN cc-by PLoS Medicine 2019-12-17

Lactate derived from aerobic glycolysis is crucial for DNA damage repair and chemoresistance. Nevertheless, it frequently noted that cancer cells depend on glutaminolysis to replenish essential metabolites. Whether how might enhance lactate production facilitate in remains unknown. Here, shown malate enzyme 2 (ME2), which metabolizes glutamine-derived pyruvate, contributes chemotherapy resistance ovarian cancer. Mechanistically, reduces the expression of glucose transporters impairs uptake...

10.1002/advs.202416467 article EN cc-by Advanced Science 2025-02-14

Objective To examine the influence of childhood obesity on early onset puberty and sex hormones in girls. Methods Healthy girls with different percentages body fat at baseline (40 obese, 40 normal, lean) were recruited from three elementary schools Shenyang, China. These (mean age 8.5 years) also matched by height, school grade, Tanner stage, family economic status baseline. Anthropometry, characteristics, hormone concentrations measured each follow-up visit. The generalized estimating...

10.1371/journal.pone.0134656 article EN cc-by PLoS ONE 2015-08-06

Background: Sugar-sweetened beverage taxes are a rapidly growing policy tool and can be based on absolute volume, sugar content tiers, or content. Yet, their comparative health economic impacts have not been quantified, in particular, tiered that provide industry incentives for reduction. Methods: We estimated incremental changes diabetes mellitus cardiovascular disease, quality-adjusted life-years, costs, cost-effectiveness of 3 sugar-sweetened tax designs the United States, basis (1)...

10.1161/circulationaha.119.042956 article EN Circulation 2020-06-22

Background: In China, and in Shandong province, the proportionate contribution of birth defects to infant mortality has increased, congenital heart disease (CHD) is now most common cause defects. The approximately 90% cases multifactorial. Little known about modifiable environmental risk factors or regional differences. We investigated putative for province China order improve prevention CHD.Methods: conducted a hospital-based 1:2 matched case–control study 164 patients with diseases 328...

10.2188/jea.je20080039 article EN cc-by Journal of Epidemiology 2009-01-01

Up to date, most of previous studies about Chinese prehypertension were conducted based on a small sample or in only one province, which could not represent the general population China. Furthermore, no information ethnic difference prevalence has been reported The aim this study is examine sex-specific, age-specific and ethnic-specific associated risk factors large-scale multi-ethnic adult population. subjects came from survey physiological constants health conditions six provinces. 47, 495...

10.1186/s12889-016-3411-4 article EN cc-by BMC Public Health 2016-08-11

Excess added sugars, particularly from sugar-sweetened beverages, are a major risk factor for cardiometabolic diseases including cardiovascular disease and type 2 diabetes mellitus. In 2016, the US Food Drug Administration mandated labeling of sugar content on all packaged foods beverages. Yet, potential health impacts cost-effectiveness this policy remain unclear.A validated microsimulation model (US IMPACT Policy model) was used to estimate mellitus cases averted, quality-adjusted...

10.1161/circulationaha.118.036751 article EN Circulation 2019-04-15

10.1093/ajcn/nqab129 article EN publisher-specific-oa American Journal of Clinical Nutrition 2021-04-02
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