Pamela L. Lutsey
A5082266331- Cardiovascular Health and Risk Factors
- Atrial Fibrillation Management and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Vitamin D Research Studies
- Cardiovascular Disease and Adiposity
- Nutritional Studies and Diet
- Blood Pressure and Hypertension Studies
- Parathyroid Disorders and Treatments
- Dementia and Cognitive Impairment Research
- Health, Environment, Cognitive Aging
- Obstructive Sleep Apnea Research
- Magnesium in Health and Disease
- Cardiac Health and Mental Health
- Cardiac Arrhythmias and Treatments
- Cardiovascular Health and Disease Prevention
- Health disparities and outcomes
- Acute Ischemic Stroke Management
- Sleep and related disorders
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cardiovascular Function and Risk Factors
- Heart Rate Variability and Autonomic Control
- Blood Coagulation and Thrombosis Mechanisms
- Bone health and osteoporosis research
- Obesity, Physical Activity, Diet
University of Minnesota
2016-2025
Twin Cities Orthopedics
2014-2025
Minnesota Department of Health
2016-2025
University of Minnesota System
2008-2025
University of Mississippi Medical Center
2014-2023
University of North Carolina at Chapel Hill
2008-2023
Jackson Memorial Hospital
2017-2023
Optum (United States)
2016-2023
National Institute of Neurological Disorders and Stroke
2023
University of California, Davis
2023
The American Heart Association, in conjunction with the National Institutes of Health, annually reports on most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, weight) factors (cholesterol, blood pressure, glucose control) that contribute health. Statistical Update presents latest data a range major clinical circulatory disease conditions (including congenital rhythm disorders,...
The American Heart Association, in conjunction with the National Institutes of Health, annually reports most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, weight) factors (cholesterol, blood pressure, glucose control) that contribute health. Statistical Update presents latest data on a range major clinical circulatory disease conditions (including congenital rhythm disorders,...
Data for front-line health-care workers and risk of COVID-19 are limited. We sought to assess among compared with the general community effect personal protective equipment (PPE) on risk.
Background— The role of diet in the origin metabolic syndrome (MetSyn) is not well understood; thus, we sought to evaluate relationship between incident MetSyn and dietary intake using prospective data from 9514 participants (age, 45 64 years) enrolled Atherosclerosis Risk Communities (ARIC) study. Methods Results— Dietary was assessed at baseline via a 66-item food frequency questionnaire. We used principal-components analysis derive “Western” “prudent” patterns 32 groups evaluated 10...
There is limited research on racial/ethnic variation in sleep disturbances. This study aimed to quantify the distributions of objectively measured disordered breathing (SDB), short duration, poor quality, and self-reported disturbances (e.g., insomnia) across groups. Cross-sectional study. Six US communities. Racially/ethnically diverse men women aged 54–93 y Multi-Ethnic Study Atherosclerosis Sleep Cohort (n = 2,230). N/A. Information from polysomnography-measured SDB, actigraphy-measured...
OBJECTIVE We determined associations between diet soda consumption and risk of incident metabolic syndrome, its components, type 2 diabetes in the Multi-Ethnic Study Atherosclerosis. RESEARCH DESIGN AND METHODS Diet was assessed by food frequency questionnaire at baseline (2000–2002). Incident identified three follow-up examinations (2002–2003, 2004–2005, 2005–2007) as fasting glucose >126 mg/dl, self-reported diabetes, or use medication. Metabolic syndrome (and components) defined...
Vitamin D is a steroid hormone precursor that associated with range of human traits and diseases. Previous GWAS serum 25-hydroxyvitamin concentrations have identified four genome-wide significant loci (GC, NADSYN1/DHCR7, CYP2R1, CYP24A1). In this study, we expand the previous SUNLIGHT Consortium discovery sample size from 16,125 to 79,366 (all European descent). This larger yields two additional harboring variants (P = 4.7×10
The association between late-life blood pressure (BP) and cognition may depend on the presence chronicity of past hypertension. Late-life declines in following prolonged hypertension be associated with poor cognitive outcomes.To examine midlife to BP patterns subsequent dementia, mild impairment, decline.The Atherosclerosis Risk Communities prospective population-based cohort study enrolled 4761 participants during (visit 1, 1987-1989) followed-up over 6 visits through 2016-2017 6). was...
To identify systematic biases across groups in objectively and subjectively measured sleep duration. We investigated concordance of self-reported habitual duration compared with actigraphy- single-night in-home polysomnography (PSG) white, black, Hispanic, Chinese participants the Multi-Ethnic Study Atherosclerosis. Among 1910 adults, duration, determined by differences between bed wake times, was overestimated all racial PSG actigraphy. Compared whites (ρ = 0.45), correlations were...
<h3>Importance</h3> Identifying modifiable risk factors that are associated with dementia burden across racial and ethnic groups in the population can yield insights into potential effectiveness of interventions preventing reducing disparities. <h3>Objective</h3> To calculate attributable fraction (PAF) 12 established for all US adults, as well separately by race ethnicity. <h3>Design, Setting, Participants</h3> This cross-sectional study used survey data from nationally representative...
Good sleep is essential for health, yet associations between and dementia risk remain incompletely understood. The Sleep Dementia Consortium was established to study polysomnography (PSG)-derived the of related cognitive brain magnetic resonance imaging endophenotypes.
Accumulating evidence supports a link between sleep disorders, disturbed sleep, and adverse brain health, ranging from stroke to subclinical cerebrovascular disease cognitive outcomes, including the development of Alzheimer disease-related dementias. Sleep disorders such as sleep-disordered breathing (eg, obstructive apnea), other disturbances, well, some which are also considered insomnia, fragmentation, circadian rhythm extreme duration), have been associated with health. Understanding...
Background Sleep irregularity has been linked to incident cardiovascular disease. Less is known about associations of sleep regularity with atherosclerosis. We examined cross‐sectional actigraphy‐assessed duration and timing subclinical atherosclerosis in the community‐based MESA (Multi‐Ethnic Study Atherosclerosis). Methods Results Ancillary participants (N=2032; mean age, 68.6±9.2 years; 37.9% White) completed 7‐day wrist actigraphy. Participants underwent assessments coronary artery...
Importance Hearing loss treatment delays cognitive decline in high-risk older adults. The preventive potential of addressing hearing on incident dementia a community-based population adults, and whether it varies by method measurement, is unknown. Objective To calculate the attributable fraction associated with adults to investigate differences age, sex, self-reported race, measurement. Design, Setting, Participants This prospective cohort study was part Atherosclerosis Risk Communities...
We examined the relationship between whole grain intake and obesity, insulin resistance, inflammation, diabetes subclinical CVD using baseline data from Multi-Ethnic Study of Atherosclerosis. Whole was measured by a 127-item FFQ in 5496 men women free CHD previously known diabetes. Mean 0·5 ( sd 0·5) servings per d; biochemical measures reflect fasting levels. After adjustment for demographic health behaviour variables, mean differences highest quintile minus lowest were 0·6 kg/m 2 BMI, 0·36...