A5050792181- Nutritional Studies and Diet
- Obesity, Physical Activity, Diet
- Global Public Health Policies and Epidemiology
- Global Health Care Issues
- Chronic Disease Management Strategies
- Health Systems, Economic Evaluations, Quality of Life
- Cardiovascular Health and Risk Factors
- Climate Change and Health Impacts
- Health disparities and outcomes
- Consumer Attitudes and Food Labeling
- Obesity and Health Practices
- Bariatric Surgery and Outcomes
- Diabetes Management and Education
- COVID-19 and healthcare impacts
- Healthcare cost, quality, practices
- Sodium Intake and Health
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Fatty Acid Research and Health
- Food Security and Health in Diverse Populations
- Healthcare Policy and Management
- Primary Care and Health Outcomes
- Health Promotion and Cardiovascular Prevention
- Healthcare Systems and Public Health
- Cancer Risks and Factors
- Employment and Welfare Studies
Imperial College London
2016-2025
Royal Society for Public Health
2025
Northumbria Healthcare NHS Foundation Trust
2021-2024
Peacocks Medical Group (United Kingdom)
2022-2024
Pfizer (United Kingdom)
2024
Pfizer (United States)
2024
Swansea University
2024
MRC Centre for Environment and Health
2019-2023
University of Wales Institute Cardiff
2022
University of Liverpool
2015-2021
Valvular heart disease (VHD) is expected to become more common as the population ages. However, current estimates of its natural history and prevalence are based on historical studies with potential sources bias. We conducted a cross-sectional analysis clinical epidemiological characteristics VHD identified at recruitment large cohort older people.We enrolled 2500 individuals aged ≥65 years from primary care screened for undiagnosed using transthoracic echocardiography. Newly (predominantly...
The Coronavirus Disease 2019 (COVID-19) pandemic has changed many social, economic, environmental and healthcare determinants of health. We applied an ensemble 16 Bayesian models to vital statistics data estimate the all-cause mortality effect for 21 industrialized countries. From mid-February through May 2020, 206,000 (95% credible interval, 178,100–231,000) more people died in these countries than would have had not occurred. number excess deaths, deaths per 100,000 relative increase were...
BackgroundDiabetes and high body-mass index (BMI) are associated with increased risk of several cancers, increasing in prevalence most countries. We estimated the cancer incidence attributable to diabetes BMI as individual factors combination, by country sex.MethodsWe population fractions for 12 cancers age sex 175 countries 2012. defined a greater than or equal 25 kg/m2. used comprehensive estimates categories 2002, assuming 10-year lag between exposure cancer, combined relative risks from...
Diabetes and high body-mass index (BMI) are associated with increased risk of several cancers, increasing in prevalence most countries. We estimated the cancer incidence attributable to diabetes BMI as individual factors combination, by country sex.
BackgroundThe prevalence of diabetes has increased in the UK and other high-income countries alongside a substantial decline cardiovascular mortality. Yet data are scarce on how these trends have changed causes death people with who traditionally died primarily vascular causes. We estimated all-cause mortality cause-specific over time, composition burden changed, this compared that non-diabetes population.MethodsIn epidemiological analysis primary care records, we identified 313 907...
Soft drinks are frequently consumed, but whether this consumption is associated with mortality risk unknown and has been understudied in European populations to date.
Multimorbidity has emerged as one of the greatest challenges facing health services, both presently and in coming decades. Surveillance data on chronic diseases Scotland, UK, estimate around four their adult population to have two or more long-term conditions.1Barnett K Mercer SW Norbury M Watt G Wyke S Guthrie B Epidemiology multimorbidity implications for care, research, medical education: a cross-sectional study.Lancet. 2012; 380: 37-43Summary Full Text PDF PubMed Scopus (3701) Google...
Introduction Standards for Reporting of Diagnostic Accuracy Study (STARD) was developed to improve the completeness and transparency reporting in studies investigating diagnostic test accuracy. However, its current form, STARD 2015 does not address issues challenges raised by artificial intelligence (AI)-centred interventions. As such, we propose an AI-specific version checklist (STARD-AI), which focuses on AI accuracy studies. This paper describes methods that will be used develop STARD-AI....
Artificial Intelligence has been applied in academic research and inference tasks across the broader economy with demonstrable success,1 but less so for core functions of public health, namely protecting promoting health populations.2
The increasing burden of multimorbidity and its socioeconomic gradient poses unique challenges to the provision structure health care. We aimed describe inequalities trends over time in prevalence, incidence, case fatality among adults all ages England using primary care electronic records.We used a random sample 991 243 individuals from Clinical Practice Research Datalink Aurum database registered at participating general practices within between Jan 1, 2004, Dec 31, 2019, linked 2015...
Life expectancy inequalities in England have increased steadily since the 1980s. Our aim was to investigate how much deaths from different diseases and injuries at ages contributed this rise inform policies that reduce health inequalities.
Accurate forecasting of cardiovascular disease mortality is crucial to guide policy and programming efforts. Prior forecasts often have not incorporated past trends in rates reduction mortality. This creates uncertainties about future disparities.To forecast US disparities 2030, we developed a hierarchical bayesian model determine incorporate prior age, period, cohort effects from 1979 2012, stratified by sex, race, which combined with expected demographic shifts 2030. Data sources included...
Large socio-economic disparities exist in US dietary habits and cardiovascular disease (CVD) mortality. While economic incentives have demonstrated success improving choices, the quantitative impact of different policies on CVD is not well established. We aimed to quantify compare potential effects total mortality specific increase fruit vegetable (F&V) consumption reduce sugar-sweetened beverage (SSB) US.Using IMPACT Food Policy Model probabilistic sensitivity analyses, we estimated...
Abstract Background Higher body mass index (BMI) and waist-to-hip ratio (WHR) increase the risk of cardiovascular disease, but extent to which this is mediated by blood pressure, diabetes, lipid traits, smoking not fully understood. Methods Using consortia UK Biobank genetic association summary data from 140,595 898,130 participants predominantly European ancestry, Mendelian randomization mediation analysis was performed investigate degree systolic pressure (SBP), an effect BMI WHR on...
BackgroundHigh-resolution data for how mortality and longevity have changed in England, UK are scarce. We aimed to estimate trends from 2002 2019 life expectancy probabilities of death at different ages all 6791 middle-layer super output areas (MSOAs) England.MethodsWe performed a high-resolution spatiotemporal analysis civil registration the Small Area Health Statistics Unit research database using de-identified deaths England 2019, with information on age, sex, MSOA residence, population...
The prevalence of type 2 diabetes (T2DM) is increasing, but increasing longevity among persons with diagnosed may be associated more extensive and diverse types morbidity. extent breadth morbidity how this varies across sub-groups unclear could have important clinical public health implications. We aimed to estimate comorbidity profiles in people T2DM variations over time.We identified approximately 224,000 the Discover-NOW dataset, a real-world primary care database from 2000 2020 covering...