Intratumoral delivery of chemotherapeutic agents may permit the localization drugs in tumors, decrease nonspecific targeting and increase efficacy.

Segmentation is considered as one of the main steps in image processing.It divides a digital into multiple regions order to analyze them.It also used distinguish different objects image.Several segmentation techniques have been developed by researchers make images smooth and easy evaluate.This paper presents literature review basic from last five years.Recent research each technique presented this paper.

Oleanolic acid (OA), which is a natural pentacyclic terpenoid, has been identified for hepato-protective, nephron-protective and cardio-tonic properties. In contrast, doxorubicin (DOX) famous anti-cancer drug but its efficacy question mark because of known cardio-toxicity. We developed combined nanoliposomal formulation DOX with OA, as adjuvant, to overwhelm toxic effects without compromising anticancer activity. The entrapment efficiency the particle size were brought in limit by...

Cellulosic biomass is considered an important and sustainable source of renewable energy, which needs a complex mixture different enzymes for its degradation. After amylase, cellulases are the second most enzymes, gain more importance due to their broad range applications at industrial level, economical environmentally friendly; researchers have focused on production cellulase with higher expression rate low cost. Pichia pastoris, methylotrophic yeast strain, has effective well-established...

Introduction: The use of electrical appliances using extremely low frequency (ELF) electromagnetic fields (EMF) has increased in the past few years. These ELF MF are reported to be linked several adverse health effects. However, only a couple studies have been conducted on association between risk tumours and electronic devices (LF) EMF. Methods: We studied common household suspected multi-hospital-based case-control study. In total, 316 patients were included final analysis. Results: study...

Doxorubicin in combination with other cytotoxic drugs has clinical advantages. However, doxorubicin-induced cardiotoxicity negatively impacts utility and outcomes. Cardiotoxicity can result from increased oxidative stress or a local cytochrome P450 mediated increase 20-hydroxy-5, 8, 11, 14-eicosatetraenoic acid (20-HETE). Oleanolic (OA) is natural pentacyclic triterpenoid free radical scavenging, cardioprotective, P450-mediated cyclooxygenase-upregulating properties. We investigated...

In the current study, alkaline hydrogen peroxide pretreated oil palm trunk fibers were subjected to ethanol production via simultaneous saccharification and fermentation (SSF). The effect of high substrate loading, enzyme feeding strategy, influence a pre-hydrolysis step in SSF was studied scale up production. addition an at start fed-batch significantly (p < 0.05) increased concentration 51.05 g/L, productivity (QP ) 0.61 g/L·h, yield (YP/S) 0.31 g/g, with theoretical 60.65%. Furthermore,...

The construction project delays can be defined as an extension of time beyond the contractual agreed during tender stage, in past decade almost 70% mega projects experienced overruns. professionals have specified that they been facing average delay 10 to 30% from original duration project. In modern building MEP (Mechanical, Electrical and Plumbing) system installation phase are exceeding due complexity mechanized application services projects. This study investigates key challenges...

Road damage detection (RDD) through computer vision and deep learning techniques can ensure the safety of vehicles humans on roads. Integrating unmanned aerial (UAVs) in RDD infrastructure evaluation (IE) has also emerged as a key enabler, contributing significantly to data acquisition real-time monitoring road damages such potholes, cracks, surface anomalies, facilitating proactive maintenance improved conditions. These UAVs are low-powered resource-constrained devices that work...

This paper introduces a procedure for glaucoma exposure by computing cup to disk ratio low contrast digital fundus images. The designated approach is based on pre-processing, processing and post steps. Pre-processing consists of enhancing optic using brightness preser ving dynamic fuzzy histogram equalization (BPDFHE) regions, the step involves segmentation will finally measure given image detect in image. method was successful 381 images out 403, achieving 98.20% sensitivity, 96.70%...

Purpose The change in climate and depletion of natural resources because the harmful emissions from different materials becomes a main issue for globe. Some developed developing countries have focused on this performed research to provide solution. purpose study is identify best types concrete based its impact environment economy. Design/methodology/approach life cycle assessment cost analysis six mixtures that include construction demolition wastes (CDW), marble sludge, rice husk bagasse...

Low birth weight in new born is major reason of neonatal deaths resulting severe short term and long effect on babies. Descriptive study conducted with the help questionnaires to factors contributing deliver low babies, investigating interrelationships among different effecting LBW increasing awareness expecting mothers. Data was collected from June September 2013. A total 140 were filled three tertiary care hospitals after taking informed consent form participants. Outcomes included that...

Overexpression of Bmi1 gene is an important feature cancer stem cell in various human tumors. Therefore, can be a potential target for small interfering RNA (siRNA) mediated therapy. Ursolic acid (UA) as natural product plays pivotal role anti-tumor field, although its performance limited by low bioavailability and poor hydrophilicity. A folate receptor-targeted cationic liposome system was designed the purpose investigating relationship between Bmil siRNA UA. The liposomes co-delivering UA...

Substrate loading enhancement in fermenter generates difficulty mixing that results low ethanol yield owing to insufficient mass transfer. Thus, this study evaluated the efficiency of a six-blade Rushton turbine and three-blade marine type propeller 3 L stirred tank bioreactor (STBR) by using steam exploded alkaline pretreated oil palm trunk (OPT) fibers unique batch fed-batch strategy. The began with 5% (w/v) solid after 12 h simultaneous saccharification fermentation (SSF) reaction, 2.5%...

Objectives Studies assessing the association of adult cancers with extremely low frequency (ELF) magnetic fields (MF) have provided inconclusive results, probably affected by limitations such as exposure levels, confounding and various forms bias. This study investigated between residential ELF MF cancer using a design that avoids main previous studies. Methods Persons who lived in buildings indoor transformer stations during period 1971–2016 formed cohort. Their was assessed based on...

Abstract Aims The National Screening Committee (NSC), whilst recommending the use of digital mydriatic retinal photography for diabetic retinopathy screening, has not yet accepted digitally compressed images grading. By greatly reducing file size, however, compression is invaluable storage and its rapid transmission across computer networks. We undertook a study to compare different levels JPEG with original bit‐mapped image determine whether there was any loss clinical detail following...

Extremely low frequency (ELF) magnetic fields (MF) have been classified as possibly carcinogenic. This classification was mainly based on studies indicating increased risk of leukemia in children living near power lines. Increased risks adult hematological malignancies and brain tumors also reported, but the results are mixed. We assessed incidence associated with residential MF exposure. All cohort members had lived buildings indoor transformer stations (TS). exposure apartment location....