Keshav V. Shah

ORCID: 0000-0003-3315-0665
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About
Contact & Profiles
Research Areas
  • Mycobacterium research and diagnosis
  • Simulation-Based Education in Healthcare
  • Head and Neck Cancer Studies
  • Tuberculosis Research and Epidemiology
  • Surgical Simulation and Training
  • Diagnosis and treatment of tuberculosis
  • Infectious Diseases and Tuberculosis
  • Ophthalmology and Eye Disorders
  • Reconstructive Surgery and Microvascular Techniques
  • Malaria Research and Control
  • Cardiac, Anesthesia and Surgical Outcomes
  • Airway Management and Intubation Techniques
  • Pituitary Gland Disorders and Treatments
  • Complement system in diseases
  • Head and Neck Surgical Oncology
  • Cardiac Valve Diseases and Treatments
  • Global Health and Surgery
  • Salivary Gland Tumors Diagnosis and Treatment
  • Global Health Workforce Issues
  • Reconstructive Facial Surgery Techniques
  • Ultrasound in Clinical Applications
  • Mosquito-borne diseases and control
  • Meningioma and schwannoma management
  • Antibiotic Resistance in Bacteria
  • Diversity and Career in Medicine

University of Pennsylvania
2023-2024

Directorate of Medicinal and Aromatic Plants Research
2023

California University of Pennsylvania
2023

University of South Florida
2021

Center for Global Health
2021

Johns Hopkins University
2020

Johns Hopkins Medicine
2020

Loyola University Medical Center
1984

The nitroimidazole prodrugs delamanid and pretomanid comprise one of only two new antimicrobial classes approved to treat tuberculosis (TB) in 50 years. Prior vitro studies suggest a relatively low barrier resistance Mycobacterium tuberculosis, but clinical evidence is limited date. We selected pretomanid-resistant M. mutants mouse models TB using range doses. frequency spontaneous was approximately 10-5 CFU. Whole-genome sequencing 161 resistant isolates from 47 mice revealed 99 unique...

10.1128/aac.01948-20 article EN Antimicrobial Agents and Chemotherapy 2020-10-16

Importance Understanding the global barriers to otolaryngology–head and neck surgery (OHNS) care is crucial in addressing disparities access care, particularly low-income middle-income countries (LMICs). Objective To characterize comprehensive otolaryngology across World Bank income groups. Design, Setting, Participants Using an online cross-sectional survey that was administered by Global OHNS Initiative via international national professional societies, personal contacts, social media,...

10.1001/jamaoto.2025.0573 article EN JAMA Otolaryngology–Head & Neck Surgery 2025-04-24

Abstract Objective Mandibular plate reconstruction (MPR) is often indicated after tumor ablation, osteoradionecrosis excision, and traumatic bone loss to restore oral functionality facial cosmetics. There are limited analyses identifying risk factors that lead infection (PIn), exposure, removal (“plate complications”). Study Design Retrospective cohort study. Setting Academic tertiary medical center. Methods Patients who underwent MPR from 2013 2022 were identified. Risk for complications...

10.1002/ohn.928 article EN cc-by-nc Otolaryngology 2024-08-05

Major salivary gland cancers (MSGCs) are often treated with primary surgery followed by adjuvant therapy for high-risk pathology. Patients these may opt out of recommended postoperative radiation (PORT) many reasons and consequently suffer worse outcomes.Retrospective cohort study.National Cancer Database.Patients diagnosed MSGC from 2004 to 2016 were identified, overall survival risk factors refusal PORT analyzed based on demographic, socioeconomic, clinical factors. Multivariable logistic...

10.1002/ohn.285 article EN Otolaryngology 2023-02-07

Relapsing malaria caused by Plasmodium vivax is a neglected tropical disease and an important cause of worldwide. Vaccines to prevent clinical mosquito transmission are needed overcome the distinct challenges this public health problem. In vaccine immunogenicity study in mice, we examined key variables responses P. Duffy binding protein vaccine, leading candidate disease-causing blood-stages. Significant sex-dependent differences were observed B cell (CD80+) T (CD8+) central memory subsets,...

10.1016/j.vaccine.2021.03.072 article EN cc-by-nc-nd Vaccine 2021-04-08

ABSTRACT The nitroimidazole pro-drugs delamanid and pretomanid comprise one of only two new antimicrobial classes approved to treat tuberculosis (TB) in 50 years. Prior vitro studies suggest a relatively low barrier resistance Mycobacterium , but clinical evidence is limited date. We selected pretomanid-resistant M. mutants mouse models TB using range doses. frequency spontaneous was approximately 10 −5 CFU. Whole genome sequencing 161 resistant isolates from 47 mice revealed 99 unique...

10.1101/2020.09.10.292508 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2020-09-11

<h3>Objective:</h3> Importance of various investigations for diagnoses by exclusion and importance starting treatment, which might be common specific pathologies irrespective different etiologies. (in a resource-limited environment) <h3>Background:</h3> There were two cases adult women (Patient G Patient V) residing in the same neighborhood. They presented with similar complaints right-sided orbital pain, headache, sixth cranial nerve palsy. <h3>Design/Methods:</h3> On individual evaluation,...

10.1212/wnl.0000000000201916 article EN Neurology 2023-04-25
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