- Advanced Radiotherapy Techniques
- Radiation Effects and Dosimetry
- Cancer Treatment and Pharmacology
- Radiation Therapy and Dosimetry
- Prostate Cancer Diagnosis and Treatment
- Advanced X-ray and CT Imaging
- Radiation Dose and Imaging
- Analytical Chemistry and Sensors
- Medical Imaging Techniques and Applications
- Breast Cancer Treatment Studies
- Cardiac pacing and defibrillation studies
- Lung Cancer Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- HER2/EGFR in Cancer Research
- Colorectal Cancer Treatments and Studies
- Lung Cancer Treatments and Mutations
- Prostate Cancer Treatment and Research
- Cancer Immunotherapy and Biomarkers
- Particle accelerators and beam dynamics
- Radiopharmaceutical Chemistry and Applications
- Neuroblastoma Research and Treatments
- Spectroscopy and Laser Applications
- Calibration and Measurement Techniques
- BRCA gene mutations in cancer
- Thyroid Cancer Diagnosis and Treatment
Hospital Universitario de Fuenlabrada
2011-2022
Universidad Complutense de Madrid
2020-2022
Complejo Hospitalario de Salamanca
2021
GEICAM – Spanish Breast Cancer Group
2014
Research Institute Hospital 12 de Octubre
2007-2011
Complejo Hospitalario de Ourense
2005
Hospital Universitario 12 De Octubre
2000
Hospital Clínico Universitario de Caracas
1951
Hospital Oncológico Andrés Grillasca
1951
Infants and children are a higher risk population for radiation cancer induction compared to adults. Although some values on pediatric patient doses cardiac procedures have been reported, data determine reference levels scarce, especially when those available adults in diagnostic therapeutic procedures. The aim of this study is make new contribution the scarce published help determination future dose levels. This paper presents set values, terms air kerma area product (KAP) entrance surface...
One of the most important aspects in metrology radiation fields is problem measurement dose profiles regions where gradient large. In such zones, 'detector size effect' may produce experimental measurements that do not correspond to reality. Mathematically it can be proved, under some general assumptions spatial linearity, disturbance induced by effect finite detector equal convolution real profile with a representative kernel detector. this work exact relation between measured and shown,...
1015 Background: Platinum salts are active in basal-like breast cancer preclinical models and has been widely used clinical trials this subtype. However its utility added to conventional drugs never tested a randomized trial. This study investigates the benefit of addition carboplatin neoadjuvant CT patients. Methods: Patients (Pt) with tumors ≥ 2 cm (or less positive axilla) immunophenotypically defined disease (ER-/PR-/HER2-/Cytokeratin 5/6+ and/or EGFR+) assessed central laboratory were...
Purpose The aim of this work is to develop a sensitometry model EBT 2 and 3 radiochromic films based on the observation that radiation induces growth two polymer color phases. Methods Previously published data active layer absorption spectrum have been used characterize contribution total absorbance each phase. Through prior proposed external beam therapy has deconvolved into phase contributions. integral in visible calculated parametrized as an absorbed dose function. A employing linear...
Radiochromic film in conjunction with flatbed scanners are frequently employed as dosimeters for advanced techniques radiotherapy. Their strengths follows: light element composition, low energy dependence, near biological tissue equivalence and high spatial resolution. However, they have some weaknesses well: non-uniformities, read out noise, scanning artifacts. Several processing protocols been proposed intending to correct the perturbations these produce. The aim of this paper is present a...
The aim of this work is to study a new analytical model which describes the dose-response curve in megavoltage photon beams radiochromic EBT3 film measured with two commercially available flatbed scanners. This takes into account different increase number types absorbents absorbed dose and it allows identify parameters that depend on scanner model, exclusively production lot. In addition, also compared other models commonly used literature terms its performance reducing systematic...
1024 Background: Triple negative breast cancer (TNBC) is a heterogeneous disease with distinct molecular subtypes that differentially respond to chemotherapy (CHT) and targeted agents. In recent study, Lehmann et al. (JCI 2011) identified six of TNBC, characterized on the basis gene ontologies differential expression. However, their clinical utility remains unclear. We aimed explore relevance these in TNBC determining differences response neoadjuvant randomized phase II trial, GEICAM/...