A5066163889- Congenital Heart Disease Studies
- Cardiovascular Function and Risk Factors
- Pulmonary Hypertension Research and Treatments
- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Coronary Interventions and Diagnostics
- Cardiac Valve Diseases and Treatments
- Elasticity and Material Modeling
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Lung Cancer Diagnosis and Treatment
- Advanced Numerical Methods in Computational Mathematics
- RNA modifications and cancer
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Advanced Mathematical Modeling in Engineering
- Lung Cancer Treatments and Mutations
- Vascular anomalies and interventions
- Nanoplatforms for cancer theranostics
- Bone and Joint Diseases
- Cancer, Hypoxia, and Metabolism
- Renal and Vascular Pathologies
- Cardiac, Anesthesia and Surgical Outcomes
- Cancer, Lipids, and Metabolism
- Circular RNAs in diseases
- Connective tissue disorders research
The University of Texas Rio Grande Valley
2025
Lanzhou University
2025
Lanzhou University Second Hospital
2025
Stanford University
2015-2024
Zhengzhou Children's Hospital
2024
Zhengzhou University
2024
Tianjin Medical University
2021-2024
Tongji University
2024
Guangdong Medical College
2024
Palo Alto University
2020-2024
Background: Rheumatoid arthritis is a chronic disabling disease characterized by inflammation, articular cartilage destruction, and reduced bone mass. Multiple studies have revealed that the development of osteoporosis in rheumatoid (RA; ORA) patients could be led to quality life increased healthcare costs. Nevertheless, no attempt has been made analyze field ORA research with bibliometric method. This study aimed provide comprehensive overview knowledge structure theme trends from...
A growing body of research has illuminated that photodynamic therapy (PDT) serves as an important therapeutic strategy in oncology and become a hot topic recent years. Although numerous papers related to cancer PDT (CPDT) have been published, no bibliometric studies conducted summarize the landscape, highlight trends hotspots this field. This study collected 5,804 records on CPDT published between 2000 2021 from Web Science Core Collection. Bibliometric analysis visualization were using...
Coronary stent design affects the spatial distribution of wall shear stress (WSS), which can influence progression endothelialization, neointimal hyperplasia, and restenosis. Previous computational fluid dynamics (CFD) studies have only examined a small number possible geometries to identify designs that reduce alterations in near-wall hemodynamics. Based on previously described framework for optimizing cardiovascular geometries, we developed methodology couples CFD three-dimensional...
Three-dimensional (3D) cardiovascular fluid dynamics simulations typically require hours to days of computing time on a high-performance cluster. One-dimensional (1D) and lumped-parameter zero-dimensional (0D) models show great promise for accurately predicting blood bulk flow pressure waveforms with only fraction the cost. They can also accelerate uncertainty quantification, optimization, design parameterization studies. Despite several prior studies generating 1D 0D comparing them 3D...
Abstract Background Osteonecrosis of the femoral head (ONFH) is a common disabling disease with considerable social and economic impacts. Although extensive studies related to ONFH have been conducted in recent years, specific bibliometric analysis on this topic has not yet performed. Our study attempted summarize comprehensive knowledge map, development landscape, future directions research approach. Methods All publications concerning published from 2001 2020 were identified Web Science...
Background: Ultrasound-triggered sonodynamic therapy (SDT), as a non-invasive approach, has attracted considerable attention in wide variety of malignant tumors and other diseases. Over the past 2 decades, number scientific publications on SDT increased rapidly. However, there is still lack one comprehensive report that summarizes global research trends knowledge landscapes field detail. Thus, we performed bibliometric analysis from 2000 to 2021 track current hotspots highlight future...
Despite the great progress of current bacterially based biotherapeutics, their unsatisfying efficacy and underlying safety problems have limited clinical application. Herein, inspired by probiotic Escherichia coli strain Nissle 1917, probiotic-derived outer membrane vesicles (OMVs) are found to serve as an effective therapeutic platform for treatment inflammatory bowel disease (IBD). To further enhance effect, OMV-encapsulating manganese dioxide nanozymes constructed, named nanoprobiotics,...
The objective of this work is to perform a virtual planning surgical repairs in patients with congenital heart diseases--to test the predictive capability closed-loop multi-scale model. As first step, we reproduced pre-operative state specific patient univentricular circulation and bidirectional cavopulmonary anastomosis (BCPA), starting from patient's clinical data. Namely, by adopting approach, boundary conditions at inlet outlet sections three-dimensional model were automatically...
Background Central nervous system tumor (CNST) is one of the most complicated and lethal forms human tumors with very limited treatment options. In recent years, growing evidence indicates that oncolytic virotherapy (OVT) has emerged as a promising therapeutic strategy for CNSTs. And considerable amount literature on OVT-CNSTs been published. However, there are still no studies summarizing global research trends hotspots this field through bibliometric approach. To fulfill knowledge gap,...
The role of nanotopographical extracellular matrix (ECM) cues in vascular endothelial cell (EC) organization and function is not well-understood, despite the composition nano- to microscale fibrillar ECMs within blood vessels. Instead, predominant modulator EC traditionally thought be hemodynamic shear stress, which uniform stress induces parallel-alignment ECs with anti-inflammatory function, whereas disturbed flow a disorganized configuration pro-inflammatory function. Since acts on by...
Objectives: During a pulmonary hypertensive crisis, the marked increase in vascular resistance can result acute right ventricular failure and death. Currently, there are no therapeutic guidelines for managing an crisis. This pilot study examined hemodynamic effects of phenylephrine, arginine vasopressin, epinephrine pediatric patients with hypertension. Design: In this prospective, open-label, nonrandomized study, we enrolled previously diagnosed who were scheduled electively cardiac...
Background Despite favorable outcomes of surgical pulmonary artery (PA) reconstruction, isolated proximal stenting the central PAs is common clinical practice for patients with peripheral PA stenosis in association Williams and Alagille syndromes. Given technical challenges reconstruction morbidities associated transcatheter interventions, hemodynamic consequences all treatment strategies must be rigorously assessed. Our study aims to model, assess, predict interventions these patients....
DLD is a key gene involved in "cuproptosis," but its roles tumor progression and immunity remain unclear. Exploring the potential mechanisms biological of may provide new insights for therapeutic strategies tumors. In present study, we analyzed role variety tumors by using several bioinformatic tools. The results showed that compared with normal tissues, tissues representing multiple cancers significant differential expression DLD. High was associated good prognosis BRCA, KICH, LUAD....
Single ventricle heart defects are among the most serious congenital diseases, and uniformly fatal if left untreated. Typically, a three-staged surgical course, consisting of Norwood, Glenn, Fontan surgeries is performed, after which superior vena cava (SVC) inferior (IVC) directly connected to pulmonary arteries (PA). In an attempt improve hemodynamic performance hepatic flow distribution (HFD) patients, novel Y-shaped graft has recently been proposed replace traditional tube-shaped...
Pathological high shear stress (HSS, 100 dyn/cm