A5020539547- Ion channel regulation and function
- Neuroscience and Neuropharmacology Research
- Genomics, phytochemicals, and oxidative stress
- Bone Tissue Engineering Materials
- Cardiac electrophysiology and arrhythmias
- Sexual function and dysfunction studies
- Bone Metabolism and Diseases
- Signaling Pathways in Disease
- Cellular transport and secretion
- Endodontics and Root Canal Treatments
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Laser Applications in Dentistry and Medicine
- Protein Kinase Regulation and GTPase Signaling
- Dental Erosion and Treatment
- Melanoma and MAPK Pathways
- Bone health and treatments
- Mast cells and histamine
- Protease and Inhibitor Mechanisms
- Bone and Dental Protein Studies
- Food Allergy and Anaphylaxis Research
- Alzheimer's disease research and treatments
- Enzyme function and inhibition
- Blood Coagulation and Thrombosis Mechanisms
- Lysosomal Storage Disorders Research
- Dental materials and restorations
Universidade Federal de São Paulo
2017-2022
Universidade Federal de Uberlândia
2018
Institute of Biomedical Science
2018
The tissue engineering of dental oral is tackling significant advances and the use stem cells promises to boost therapeutical approaches regenerative dentistry. Despite in this field, literature still scarce regarding modulatory effect laser photobiomodulation (PBM) on genes related inflammation osteogenesis Postnatal Human Dental Pulp Stem (DPSCs). This study pointedly investigated PBM treatment proliferation, growth differentiation factors, mineralization, extracellular matrix remodeling...
Mucopolysaccharidosis type I (MPS I) is caused by genetic deficiency of α-l-iduronidase and impairment lysosomal catabolism heparan sulfate dermatan sulfate. In the brain, these substrates accumulate in lysosomes neurons glial cells, leading to neuroinflammation neurodegeneration. Their storage also affects homeostasis-inducing activity several proteases including cathepsin B (CATB). central nervous system, increased CATB has been associated with deposition amyloid plaques due an alternative...
Protease-activated receptors (PARs) are G protein–coupled receptors, which activated by proteolytical cleavage of the amino-terminus and act as sensors for extracellular proteases. We hypothesized that PAR-1 PAR-2 can be modulated inflammatory stimulus in human dental pulp cells. gene expression tissue MDPC-23 cells were analyzed quantitative polymerase chain reaction. Monoclonal antibodies used to investigate cellular these using Western blot, flow cytometry, confocal microscopy...
Mast cell and testosterone interactions involved in renal fibrosis rats subjected to unilateral ureteral obstruction (UUO) were investigated. Orchiectomized (ORX) nonorchiectomized Wistar UUO, a group was sham-operated (control: SO). Animals from the UUO treated with saline or sodium cromoglycate (CG). Some ORX CG groups also received propionate replacement (TR). Kidneys blood collected 14 d after SO. Kidney sections stained toluidine blue quantify mast cells, picrosirius red used for...
Anna A. Oleshkevich, Specific features of change in enzymate activity