A5101866141- Traditional Chinese Medicine Studies
- MicroRNA in disease regulation
- Pulmonary Hypertension Research and Treatments
- Garlic and Onion Studies
- Pediatric health and respiratory diseases
- Lung Cancer Research Studies
- Heart Rate Variability and Autonomic Control
- Hops Chemistry and Applications
- Medical Research and Treatments
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Polyamine Metabolism and Applications
- Inflammatory mediators and NSAID effects
- Chemotherapy-induced organ toxicity mitigation
- Signaling Pathways in Disease
- Vitamin C and Antioxidants Research
- Infrared Thermography in Medicine
- Circular RNAs in diseases
- Neuropeptides and Animal Physiology
- Respiratory Support and Mechanisms
- Bioactive Compounds in Plants
- Traumatic Brain Injury and Neurovascular Disturbances
- Traditional Chinese Medicine Analysis
- High Altitude and Hypoxia
- Biofield Effects and Biophysics
- Pharmacological Receptor Mechanisms and Effects
Wuhan University
2024-2025
Renmin Hospital of Wuhan University
2024-2025
Nanjing University of Chinese Medicine
2009-2024
Jiangsu Province Hospital
2010-2018
Xinxiang Medical University
2015
Jiangsu Provincial Hospital of Traditional Chinese Medicine
2009
Nanjing University
2007
Autonomic nervous system imbalance is intricately associated with the severity and prognosis of pulmonary arterial hypertension (PAH). Carotid baroreceptor stimulation (CBS) a nonpharmaceutical intervention for autonomic neuromodulation. The effects CBS on monocrotaline-induced PAH were investigated in this study, its underlying mechanisms elucidated. results indicated that improved hemodynamic status alleviated right ventricular dysfunction, improving remodeling remodeling, thus enhancing...
Gut microbiota and its metabolites, as well the intestinal barrier, play important roles in development of obesity-related hypertension. Sympathetic nerves are critical for homeostasis. Carotid baroreceptor stimulation (CBS) has been shown to exert protective effects against hypertension via sympathetic tone reduction. This study aimed reveal CBS treatment on homeostasis underlying mechanisms An animal model was established with Sprague-Dawley rats by a high-fat diet 10% fructose solution 13...
The aim of this study was to investigate the protective effects thymoquinone treatment on cholestatic rats with liver injury.Thirty-two Sprague-Dawley were divided randomly into four groups: normal control, bile duct ligation model low-dose (25 mg/kg), and high-dose (50 mg/kg).Thymoquinone gavage administered continuously 3 days before ligation, saline, at same volume, control group.The sacrificed after 2 weeks treatment, tissues obtained frozen.The contents hydroxyproline (HP),...
Purpose: To investigate the effect of compound xiebai capsule (CXC) on pulmonary arterial vascular remodeling in a rat model monocrotaline-mediated hypertension (PAH).Methods: PAH was established through intraperitoneal injection MCT (60 mg/kg) to male Sprague-Dawley rats. Thereafter, rats were grouped and treated with saline (control), nifedipine at dose 0.02 g/kg/day (positive control), or different doses CXC (0.67, 1.00 1.32 g/kg/day). The treatments determined by measurement hemodynamic...
Obesity-associated cardiac remodeling is characterized by sympathetic nerve over-activation and pro-inflammatory macrophage infiltration. We identified norepinephrine (NE), a neurotransmitter, as effector to activate NLRP3 inflammasome, which contributed inflammation. In vivo, Sprague-Dawley (SD) rats were fed high-fat diet (HFD) for 12 weeks establish obese rat models. Obese exhibited marked hypertrophy compared normal rats. The expression of interleukin (IL)-1β was upregulated, accompanied...
Objective: This study utilized transcriptomic sequencing combined with cellular and animal models to explore the potential mechanisms of Xuebijing in treating sepsis-induced myocardial dysfunction, also known as injury. Methods: We investigated targets regulatory XBJ injection using network pharmacology RNA sequencing. The effects on oxidative stress apoptosis levels human cardiac myocytes (AC16) C57BL/6 mice exposed lipopolysaccharide (LPS) were evaluated by Enzyme-Linked Immunosorbent...
Objective: The main objective is to study the electrodermal energy wave at some acupuncture points on Chinese people with different ages. Methods: screening device MORA-Super (German) was applied measure 38 and nonacupuncture 3949 candidates. Results: There are five groups, including 17 cases ≤12 year, 41 between 13 18 years, 722 19 39 2995 40 59 174 ≥60 years. of candidates older than 60 years increased significantly compared other groups (P < 0.01). positive correlation age (R = 0.582)....