A5018314887- Hepatitis C virus research
- Hepatitis B Virus Studies
- Hepatitis Viruses Studies and Epidemiology
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Viral gastroenteritis research and epidemiology
- Global Health Workforce Issues
- Liver Diseases and Immunity
- Employment and Welfare Studies
Japanese Red Cross Society, Japan
2019-2023
Abstract Background More than 45 cases of transfusion‐transmitted hepatitis E virus infection (TT‐HEV) have been reported in Japan. Therefore, 2020, universal individual donation nucleic acid amplification testing (ID‐NAT) was implemented for HEV. Study Design and Methods We characterized HEV NAT‐positive blood donors. The number new infections the asymptomatic rate were estimated using rate. RNA quantitation, phylogenetic analysis, antibody tests performed, residual risk TT‐HEV assessed...
Abstract Background In Japan, 41 million blood donations have been screened for hepatitis B virus (HBV) during the past 8.4 years using individual donation nucleic acid amplification testing (ID‐NAT) and antibody to core antigen (anti‐HBc) screening. Study Design Methods Transfusion‐transmitted HBV infection (TT‐HBV) incidence was examined. Donated implicated in TT‐HBV analyzed stage DNA levels. Causative strains were phylogenetically analyzed. Results Among 5162 (0.013%) ID‐NAT positives,...
Hepatitis B virus (HBV)-positive individuals with isolated anti-HBs are found among HBV vaccine recipients and healthy blood donors no vaccination history. infectivity from transfusions derived such remains unclear.A male patient who received transfusion negative for individual donation-NAT, HBsAg anti-HBc but weakly positive developed typical transfusion-transmitted (TT)-HBV response. The responsible donor was a frequent repeat showing marked increase in titer without response 84 days after...
Hepatitis A virus (HAV) has begun to spread globally among men who have sex with (MSM). E (HEV) also may be transmitted through sexual contact MSM. To assess the current status of these viruses MSM in Japan, seroprevalence both using 503 plasma samples collected between 2009 and 2018 from human immunodeficiency (HIV)-positive male donors were presumed mainly was investigated. Our results suggested that HAV spreading within this population, as reported elsewhere. By contrast, HEV confirmed...
E型肝炎ウイルス（HEV）の輸血感染対策を検討するため，輸血後E型肝炎感染患者として，既報（Transfusion 2017）の19例も含め，2018年までに判明した34症例について解析した．
Abstract Background The occurrence of transfusion‐transmitted hepatitis B virus (HBV) infection has fallen dramatically due to continuous improvements in pre‐transfusion laboratory testing. However, the characteristics HBV caused by individual donor nucleic acid amplification test (ID‐NAT)‐negative blood products are unclear. Case Presentation A 76‐year‐old woman with acute myeloid leukemia was diagnosed after receiving apheresis platelets derived from an ID‐NAT‐negative donation. This case...