A5087111736- Kawasaki Disease and Coronary Complications
- Coronary Artery Anomalies
- Viral Infections and Immunology Research
- Cardiac Structural Anomalies and Repair
- Congenital Heart Disease Studies
- Cardiovascular Effects of Exercise
- COVID-19 Clinical Research Studies
- Pericarditis and Cardiac Tamponade
- Heart Failure Treatment and Management
- Mechanical Circulatory Support Devices
- Receptor Mechanisms and Signaling
- Infective Endocarditis Diagnosis and Management
- Neonatal and fetal brain pathology
- Cardiac Valve Diseases and Treatments
- Pharmaceutical studies and practices
- Antibiotics Pharmacokinetics and Efficacy
- Pulmonary Hypertension Research and Treatments
- Inflammasome and immune disorders
- Myasthenia Gravis and Thymoma
- Cardiac pacing and defibrillation studies
- Tuberous Sclerosis Complex Research
- Ion Transport and Channel Regulation
- Vascular Tumors and Angiosarcomas
- Neonatal Respiratory Health Research
- Tracheal and airway disorders
Institute of Public Health of Serbia
2011-2024
University of Belgrade
2013-2022
University of Belgrade – Faculty of Medicine
2018
Institut za Zdravstvenu Zastitu Majke i Deteta
2018
Oncology Institute of Vojvodina
2013
Background: Acute myocarditis (AM) is defined as inflammation of the myocardium. The aim our study a comparative analysis differences between AM related and unrelated to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Methods: retrospective included children with treated from January 2018 November 2020. Results: 24 patients; 7 had SARS-CoV-2 they were older than 7. They more likely have abdominal pain ( P = 0.014), headache 0.003), cutaneous rash conjunctivitis while fulminant...
Background: Cardiovascular complications with myocarditis in multisystem inflammatory syndrome children (MIS-C) associated severe acute respiratory coronavirus 2 infection have been reported, but the optimal therapeutic strategy remains unknown. Methods: A retrospective cohort study included 19 patients left ventricular systolic dysfunction MIS-C, average years of age 13.2 ± 3.8, treated from April 2020 to 2021. Results: Treatment failure (TF) was observed 8 (in intravenous immunoglobulin...
Cardiac rhabdomyomas are common in tuberous sclerosis. We report a child who developed rhabdomyoma related arrhythmia refractory to antiarrhythmic drug therapy. Reversion of the atrial ectopic tachycardia was achieved with mammalian target rapamycin pathway ( mTOR ) inhibitor sirolimus. As per our knowledge, this is first time that sirolimus has been successfully used setting.
Background: The angiotensin-converting enzyme inhibitor (ACEI) enalapril is often administered to infants and young children with heart failure (HF) in various dosing regimens formulations not adapted for their age. Methods: This prospective, two-center, open-label 8-week study evaluated an age-appropriate formulation of orodispersible minitablets (ODMTs) (0.25 mg 1 mg) aged 0 6 years HF due congenital disease. An age/weight-based schedule was followed. Measures echocardiographic parameters,...
The predisposing factors for pericarditis recurrence in the pediatric population have not yet been established. This study aimed to define risk unfavorable prognosis of acute pericarditis.This was a retrospective that included all patients with treated from 2011 2019 at tertiary referent center.The 72 children. Recurrence observed 22.2% patients. Independent were: erythrocyte sedimentation rate≥50mm/h (p=0.003, OR 186.3), absence myocarditis (p=0.05, 15.2), C-reactive protein≥125mg/L...
Background and Objectives: Recurrence of pericarditis (ROP) is an important complication the acute pericarditis. The aim this study was to analyse influence aetiology, clinical findings treatment on outcome Methods: Data were retrospectively collected from medical records patients treated 2011 2019 at a tertiary referent heart paediatric center. Results: Our investigation included 56 children with idiopathic viral Relapse registered in 8/56 patients, 2/29 (7.41%) nonsteroidal...
There are no more than 20 antenatally diagnosed aorto-left ventricular tunnel cases reported in the literature. In most of them diagnosis was made indirectly and only after multiple fetal scans based on findings such as thick dilated left ventricle grossly ascending aorta. We present a patient whom direct visualization at 30th gestation week single scan using recently introduced `cockade sign`. Clinical implications antenatal postnatal treatment outcome also discussed.
Multisystem inflammatory syndrome in children (MIS-C) associated with being infected coronavirus-19 (COVID-19) is a life-threatening condition resulting from cytokine storm, increased synthesis of reactive oxygen species (ROSs), and hyperinflammation occurring genetically predisposed following an infection SARS-CoV-2.The primary aims our study were to identify changes the activity antioxidant enzymes erythrocytes total oxidative status plasma after treated methylprednisolone (MP).A...
Myocarditis has spontaneous resolution in 50% of patients. Our study aimed to define risk factors for developing dilated cardiomyopathy (DCM) and death pediatric patients with acute myocarditis (AM). The retrospective cohort included all treated AM. Mother Child Health Institute from January 2011 March 2019. In the study, 62 were included, 40 boys 22 girls (11.15±5.86 years) Twelve out sixty-two children had fulminant myocarditis. Four died phase AM, 11 developed DCM. Follow up was...
Cardiovascular manifestations are common (35-100%) in the multisystem inflammatory syndrome children. Our study aimed to analyze treatment impact and cardiovascular involvement patients with The retrospective cohort included 81 treated between April 2020 December 2021 (9.3±4.6 years). Elevated cardiac troponin I pro-B-type natriuretic peptide were observed 34.2% 88.5% of patients, respectively. Myocardial dysfunction was 50.6%. Children older than 10 years had a 4-fold increased risk...
Background: In multisystem inflammatory syndrome in children (MIS-C) temporarily associated with coronavirus disease-19 (COVID-19), myocardial damage has been reported. Materials and Methods: A retrospective observational cohort study included under 18 who had a injury related to COVID-19 treated mother child health institute from April 2020 August 2020. Myocardial was manifested by elevated serum cardiac troponin NT-proBNP LV dysfunction, arrhythmias, coronary arteries (CAs) dilatation or...
Myocarditis has spontaneous resolution in 50% of patients. Our study aimed to define risk factors for developing dilated cardiomyopathy (DCM) and death pediatric patients with acute myocarditis (AM). The retrospective cohort included all treated AM. Mother Child Health Institute from January 2011 March 2019. In the study, 62 were included, 40 boys 22 girls (11.15±5.86 years) Twelve out sixty-two children had fulminant myocarditis. Four died phase AM, 11 developed DCM. Follow up was...
<b>Introduction:</b> Transcatheter closure is an alternative to ventricular septal defect (VSD) occlusion surgery. Nit-Occlud Lê VSD coil a new device yet be evaluated. The study aimed evaluate immediate and midterm results after transcatheter with the device. <b>Methods:</b> retrospective analysis included 30 patients referred for during period from October 2015 December 2020. <b>Results:</b> At time of intervention, patients’ mean age body weights were 7.5 ± 5.6 years 29.3 19.1 kg....
Anomalno ishodište leve koronarne arterije iz plućne (ALCAPA) predstavlja retku kongenitalnu anomaliju, koja se javlja sa učestalošću od 1:300.000 živorođene dece i kod koje ishemija miokarda nastaje usled fenomena »koronarne krađe«.
 Dvomesečno odojče je hospitalizovano znacima teške kongestivne srčane insuficijencije, bila praćena metaboličkom acidozom, povišenim koncentracijama kardiospecifičnih enzima proteina, radiografskim uvećanjem senke elektrokardiografskim ishemije miokarda....
Introduction/Objective. The anomalous origin of the left coronary artery from pulmonary (ALCAPA) is rare congenital disease, which causes myocardial ischemia and subsequent heart failure in infants. aim early mid-term follow up evaluation function after surgical repair ALCAPA. Methods. Investigation was retrospective included medical records ALCAPA patients treated surgically, between 2009 2017, at tertiary referent center. Results. Five (four girls) with anomaly were study. All had...
Perinatal asphyxia (PA) is a condition characterized by gas exchange disorder due to lack of blood flow or exchange, with potential multiorgan dysfunction. Our study aimed determine the correlation between biochemical markers and echocardiography findings in group asphyxiated newborns. The prospective cohort included 120 neonates (52/120 PA) treated at tertial referral pediatric center, from 2012 2014. A moderate-strong positive was recorded transtricuspid pressure gradient (TRPG) serum...