- Musculoskeletal pain and rehabilitation
- Orthopedic Surgery and Rehabilitation
- Shoulder Injury and Treatment
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Elbow and Forearm Trauma Treatment
- Osteoarthritis Treatment and Mechanisms
- Total Knee Arthroplasty Outcomes
- Shoulder and Clavicle Injuries
- Spine and Intervertebral Disc Pathology
- Rheumatoid Arthritis Research and Therapies
- Health Systems, Economic Evaluations, Quality of Life
- Nerve Injury and Rehabilitation
- Inflammatory mediators and NSAID effects
- Medical Practices and Rehabilitation
- Cancer survivorship and care
- Bipolar Disorder and Treatment
- Schizophrenia research and treatment
- Mental Health Treatment and Access
- Lymphatic System and Diseases
- Pain Management and Placebo Effect
- Electroconvulsive Therapy Studies
- Diagnosis and Treatment of Venous Diseases
- Clinical practice guidelines implementation
- Complementary and Alternative Medicine Studies
- Healthcare and Venom Research
Stiftung für Forschung in Spätantike und Mittelalter HR. Sennhauser
2011-2024
University Hospital of Zurich
2002-2017
Zürcher RehaZentrum Davos
2006-2017
Rehabilitation Foundation
2017
Creative Commons
2017
North American Spine Society
2017
University of Zurich
1997-2017
Klinik Hirslanden
2017
Berner Augenklinik am Lindenhofspital
2017
University of Fribourg
2017
To discuss the concepts of minimal clinically important difference (MCID) and smallest detectable (SDD) to examine their relation required sample sizes for future studies using concrete data condition-specific Western Ontario McMaster Universities Osteoarthritis Index (WOMAC) generic Medical Outcomes Study 36-Item Short Form (SF-36) in patients with osteoarthritis lower extremities undergoing a comprehensive inpatient rehabilitation intervention.SDD MCID were determined prospective study 122...
There is no data on the variation in suicide risk over lifetime and suicide-preventive effect of long-term treatment mood-disorder patients with antidepressants neuroleptics. Our research focused 186 unipolar (D), 60 bipolar II (Dm), 130 nuclear I (MD), 30 preponderantly manic (M/Md); that were followed-up from 1963 to 2003. By 2003, 45 (11.1%) 406 had committed suicide. Suicide rates highest among D (Standardized Mortality Ratio, SMR = 26.4), MD (SMR 13.6), Dm 10.6) lowest M/Md 4.7)....
To compare the responsiveness of condition-specific Western Ontario and McMaster Universities osteoarthritis (OA) index (WOMAC) generic Short Form-36 (SF-36) in patients with OA legs undergoing a comprehensive inpatient rehabilitation intervention.A prospective follow up study consecutively referred inpatients clinic was made. The included fulfilled American College Rheumatology criteria for knee or hip underwent both passive and, particularly, active physical therapy three to four weeks....
Hand strength is an important independent surrogate parameter to assess outcome and risk of morbidity mortality. This study aimed determine the predictive power cofactors predict population-based normative grip pinch strength.A representative population survey was used as basis for prediction analyses (n = 978). Bivariate relationships between grip/pinch strengths dominate hand were explored by means all relevant mathematical functions maximize prediction. The resulting best combined into a...
Objective . To cross-culturally adapt the Shoulder Pain and Disability Index (SPADI) from English into German, to test reliability validity of German version. Methods Cross-cultural adaptation SPADI was performed according international guidelines. One hundred eighteen patients who had undergone shoulder arthroplasty, on average 4 yr previously, completed a questionnaire booklet containing SPADI, Short Form 36 (SF-36), Arm, Hand (DASH) questionnaire, American Elbow Surgeons (ASES) for assess...
Background and Purpose— Outcome after first stroke varies significantly across Europe. This study was designed to compare motor functional recovery between four European rehabilitation centers. Methods— Consecutive patients (532 patients) were recruited. They assessed on admission at 2, 4, 6 months with the Barthel Index, Rivermead Motor Assessment of Gross Function, Leg/Trunk, Arm, Nottingham Extended Activities Daily Living (except admission). Data analyzed using random effects ordinal...
Abstract Objective To assess the responsiveness (sensitivity to change) of 6 shoulder outcome instruments. Methods In a prospective cohort study 153 total arthroplasties, was measured by Short Form 36 (SF‐36); Disabilities Arm, Shoulder, and Hand questionnaire (DASH); Shoulder Pain Disability Index (SPADI); American Elbow Surgeons for (ASES); Constant (Murley) Score (CS). Responsiveness mainly quantified effect sizes before months after operation. Sensitivity analysis effects receiver...
Purpose. To document the prevalence, severity and time course of anxiety depression in stroke rehabilitation patients four European countries.Method. At two, six months post-stroke, prevalence were determined 532 consecutively recruited patients, using Hospital Anxiety Depression Scale. Time was examined, Cochran-Q Friedman-tests, respectively. We identified whether numbers anxious/depressed at each point comprised same individuals.Results. Prevalence ranged between 22% 25%; 24% 30%. Median...
Although subacute and chronic gastrointestinal symptoms are very common in primary care, epidemiological date sparse. The aim of the study was to examine quantify prevalence their associations with somatic mental disorders general population. Data were collected prospectively between 1981 (age m = 22, f 23) 2008 49/50) from Zurich Cohort Study (n 292 men, 299 women), a representative population survey. participants assessed using semi-structured interview, “Structured Psychopathological...
Recent evidence shows an association between coronavirus disease 2019 (COVID-19) infection and a severe inflammatory syndrome in children. Cardiovascular magnetic resonance (CMR) data about myocardial injury children are limited to small cohorts. The aim of this multicenter, international registry is describe clinical cardiac characteristics multisystem (MIS-C) associated with COVID-19 using CMR so as better understand the real extent damage vulnerable cohort. Hundred-eleven patients meeting...
Abstract Objective To explore the physiometric and psychometric properties of clinical, generic, condition‐specific assessment instruments. describe patients' outcome after total shoulder arthroplasty. Methods Forty‐three patients were assessed in a 5–6‐year cross‐sectional catamnesis. Results With regard to joint stability, pain, general physical health, mental showed scores comparative normative scores. Significant functional limitation was evidenced by low mean on specific function scales...
Changes of health and quality-of-life in chronic conditions are mostly small require specific sensitive instruments. The aim this study was to determine compare responsiveness, i.e. the sensitivity change five outcome instruments for effect measurement pain.In a prospective cohort study, 273 pain patients were assessed on Numeric Rating Scale (NRS) pain, Short Form 36 (SF-36), Multidimensional Pain Inventory (MPI), Hospital Anxiety Depression (HADS), Coping Strategies Questionnaire (CSQ)....
Objective To determine minimal clinically important differences (MCIDs) for improvement and worsening in various health dimensions knee osteoarthritis under conservative therapy. Methods Health, symptoms function were assessed by the generic Short Form 36 condition-specific Western Ontario McMaster Universities Osteoarthritis Index n=190 patients with before after comprehensive rehabilitation intervention (3-month follow-up). By means of construct-specific transition questions, MCIDs defined...
To report on the results of consensus process integrating evidence from preliminary studies to develop first version a Comprehensive ICF Core Set and Brief for diabetes mellitus.A formal decision-making gathered was followed. Preliminary included Delphi exercise, systematic review, an empirical data collection. After training in based these relevant categories were identified by international experts different backgrounds.The set 253 at second, third, fourth levels with 99 body functions, 40...