A5031800041- Musculoskeletal pain and rehabilitation
- Intensive Care Unit Cognitive Disorders
- Spine and Intervertebral Disc Pathology
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Medical Practices and Rehabilitation
- Respiratory Support and Mechanisms
- Stroke Rehabilitation and Recovery
- Connective tissue disorders research
- Frailty in Older Adults
- Biomedical and Chemical Research
- Cerebral Palsy and Movement Disorders
- Psychosomatic Disorders and Their Treatments
- Clinical practice guidelines implementation
- Total Knee Arthroplasty Outcomes
- Complementary and Alternative Medicine Studies
- Cancer survivorship and care
- Osteoarthritis Treatment and Mechanisms
- Shoulder Injury and Treatment
- Hip disorders and treatments
- Cancer-related cognitive impairment studies
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Health and Mental Health
- Hemodynamic Monitoring and Therapy
- Sepsis Diagnosis and Treatment
University Hospital of Bern
2015-2024
University of Bern
2019-2024
Ospedale Sant'Anna
2024
Smith Family
2023
Hôpital de l'enfance
2016
Solothurner Spitäler
2014
Departamento de Epidemiología
2013
Stiftung für Forschung in Spätantike und Mittelalter HR. Sennhauser
2008-2011
Maastricht University
2008-2009
University of Zurich
2006
Introduction Neuromuscular weakness resulting in severe functional impairment is common critical care survivors. This study aimed to evaluate effects of an early progressive rehabilitation intervention mechanically ventilated adults at risk. Methods was a parallel, two-arm, assessor-blinded, randomised controlled trial with 6-months follow-up that conducted mixed ICU academic centre Switzerland. Previously independent, ventilated, critically ill expected stay ≥72 hours (n = 115) were control...
Little has been done to study the effectiveness of antidepressants in controlling anxiety/depression a population cancer patients. A double‐blind placebo‐controlled was therefore designed assess 20 mg fluoxetine. Of 115 patients who fulfilled entry criteria for levels distress, 45 were randomized fluoxetine treatment group (FA) and 46 placebo (PA) after 1‐week period exclude responders. The Montgomery Asberg Depression Scale (MADRS), Hamilton Anxiety (HAS), Hospital (HADS), Revised Symptom...
Background Virtual reality-based training has found increasing use in neurorehabilitation to improve upper limb and facilitate motor recovery. Objective The aim of this study was directly compare virtual with conventional therapy. Methods In a multi-center, parallel-group randomized controlled trial, patients at least 6 months after stroke onset were allocated either an experimental group (virtual training) or control receiving therapy (16x45 minutes within 4 weeks). system replicated...
Introduction Intensive care unit acquired weakness (ICUAW) may contribute to functional disability in ICU survivors, yet performance-based data for general patients are lacking. This study explored outcomes of (1) and risk factors (2) at discharge. Methods Data from a randomised controlled trial that investigated two early exercise regimes previously independent, ventilated adults (n = 115) without any significant outcome-differences were used the present analysis. ICUAW was clinically...
Changes of health and quality-of-life in chronic conditions are mostly small require specific sensitive instruments. The aim this study was to determine compare responsiveness, i.e. the sensitivity change five outcome instruments for effect measurement pain.In a prospective cohort study, 273 pain patients were assessed on Numeric Rating Scale (NRS) pain, Short Form 36 (SF-36), Multidimensional Pain Inventory (MPI), Hospital Anxiety Depression (HADS), Coping Strategies Questionnaire (CSQ)....
Introduction The global volume of surgery is growing and the population ageing, economic pressure rising. Major associated with relevant morbidity mortality. Postoperative reduction in physiological functional capacity especially marked elderly, multimorbid patient low fitness level, sarcopenia malnutrition. Interventions aiming to optimise prior (prehabilitation) may reduce postoperative complications consequently health costs. Methods analysis This a multicentre, multidisciplinary,...
To compare the effects of an interdisciplinary pain management programme with those standard in-patient rehabilitation by comprehensive biopsychosocial self--assessment.In this naturalistic prospective controlled cohort study, 164 chronic patients who participated in and 143 underwent were assessed using standardized instruments. Effect differences compared bivariately analysed multivariate logistic regression to control for baseline outcome variables confounders.On entry into clinic,...
This cross validation study examined the reliability of Multidimensional Pain Inventory (MPI) and stability Classification System empirically derived subgroup classification obtained by cluster analysis in chronic musculoskeletal pain. Reliability German was only once past a small sample. Previous international studies mainly involving fibromyalgia patients showed that retest resulted 33–38% being assigned to different classification. Participants were 204 persons with pain (82% non-specific...
INTRODUCTION: The present study aimed to replicate and validate the empirically derived subgroup classification based on Multidimensional Pain Inventory (MPI) in a sample of highly disabled fibromyalgia (FM) patients. Second, it examined how identified subgroups differed their response an intensive, interdisciplinary inpatient pain management program. METHODS: Participants were 118 persons with FM who experienced persistent disabled. Subgroup was conducted by cluster analysis using MPI...
Patients with non-specific back pain are not a homogeneous group but heterogeneous regard to their bio-psycho-social impairments. This study examined sample of 173 highly disabled patients chronic find out how the three subgroups based on Multidimensional Pain Inventory (MPI) differed in response an inpatient management program. Subgroup classification was conducted by cluster analysis using MPI subscale scores at entry into At program and discharge after four weeks, participants completed...
Patients after primary hip or knee replacement surgery can benefit from postoperative treatment in terms of improvement independence ambulation, transfers, range motion and muscle strength. After discharge hospital, patients are referred to different destination modalities: intensive inpatient rehabilitation (IR), cure (medically prescribed stay at a convalescence center), ambulatory (AT) home. The purpose this study was 1) measure functional health (primary outcome) function relevant...
In recent years, virtual reality has been introduced to neurorehabilitation, in particular with the intention of improving upper-limb training options and facilitating motor function recovery. The proposed study incorporates a quantitative part qualitative part, termed mixed-methods approach: (1) investigation efficacy compared conventional therapy are investigated, (2a) patients' experiences expectations (2b) therapists' using system setting. At three participating clinics, 60 patients at...
The aim of this study was to capture and understand the immediate recovery journey patients following lumbar spinal fusion surgery explore interacting constructs that shape their journey. A qualitative using Interpretive Phenomenological Analysis (IPA) approach. purposive sample 43 adult (≥16 years) undergoing ≤4 level instrumented for back and/or leg pain degenerative cause, were recruited pre-surgery from 4 UK centres. Patients completed a weekly diary expressed in own words first weeks...
Objectives The relationship between chronic pain and depression is controversial the data on association show strong variation. This study aimed to provide refined correlation regression basis of categorical continuous measures. Methods Cross-sectional assessment was based standardized instruments that measure a quasi-continuous scale, Short Form-36, Hospital Anxiety Depression Scale, Multidimensional Pain Inventory. Correlations were determined by instruments' scales, with without...
Objective: To determine and compare the sensitivity to change of condition-specific cervical Northern American Spine Society (NASS) generic Short Form 36 (SF-36). Design: Prospective cohort study. Subjects: One hundred seventy five patients after whiplash injury. Interventions: Four-week inpatient interdisciplinary pain management programme. Main measures, analysis: Responsiveness NASS SF-36 was quantified by effect size standardized response mean compared within same construct modified...
Prospective classification of patients with nonspecific chronic back pain into homogeneous subgroups might be an important objective in order to tailor interventions and improve treatment outcomes.This study investigated the effect a subgroup-specific rehabilitation program based on Multidimensional Pain Inventory (MPI) Classification System compared standard care.Single blinded, parallel group, pragmatic randomized controlled trial.Inpatient subjects clinic.A total 139 pain.Patients both...
Prolonged need for intensive care is associated with neuromuscular weakness, termed Intensive Care Unit Acquired Weakness. Those affected suffer from severe functional impairment that can persist years. First studies suggest a positive effect of physiotherapy and early mobilisation. However, the ideal intervention preferential outcome not known. So far no randomised controlled trial has been conducted to specifically evaluate an endurance resistance training in mechanically ventilated,...
Introduction There has been a 65% increase in lumbar spinal fusion surgery (LSFS) worldwide over the last 13 years, with costs of £26 million to UK National Health Service annually. Patient dissatisfaction outcome and persistent pain disability incurs further costs. Three trials provide low-quality evidence for role physiotherapy. Our surveys investigating physiotherapy/surgeon practice concluded rehabilitation should be tailored individual patient owing considerable clinical heterogeneity....