A5069412095- Chemical Synthesis and Analysis
- Iron-based superconductors research
- Peroxisome Proliferator-Activated Receptors
- Adipose Tissue and Metabolism
- Machine Learning in Bioinformatics
- Synthetic Organic Chemistry Methods
- Metabolism, Diabetes, and Cancer
- Rare-earth and actinide compounds
- Corporate Taxation and Avoidance
- Receptor Mechanisms and Signaling
- Carbohydrate Chemistry and Synthesis
- Computational Drug Discovery Methods
- Click Chemistry and Applications
- Neuropeptides and Animal Physiology
- Inflammatory mediators and NSAID effects
- Intellectual Capital and Performance Analysis
- Macrophage Migration Inhibitory Factor
- Physics of Superconductivity and Magnetism
- Asymmetric Synthesis and Catalysis
- Fluorine in Organic Chemistry
Futaba (Japan)
2022-2023
Shionogi (Japan)
2022-2023
Kyoto University
2003-2009
We report high-sensitivity microwave measurements of the in-plane penetration depth ${\ensuremath{\lambda}}_{ab}$ and quasiparticle scattering rate $1/\ensuremath{\tau}$ in several single crystals hole-doped Fe-based superconductor ${\mathrm{Ba}}_{1\ensuremath{-}x}{\mathrm{K}}_{x}{\mathrm{Fe}}_{2}{\mathrm{As}}_{2}$ ($x\ensuremath{\approx}0.55$). While a power-law temperature dependence with power $\ensuremath{\sim}2$ is found large $1/\ensuremath{\tau}$, we observe an exponential superfluid...
We have studied the lower critical fields ${H}_{c1}$ of superconducting iron oxipnictide ${\text{PrFeAsO}}_{1\ensuremath{-}y}$ single crystals for $\mathbit{H}$ parallel and perpendicular to $ab$ planes. Measurements local magnetic induction at positions straddling sample edge by using a miniature Hall-sensor array clearly resolve first flux penetration from Meissner state. The temperature dependence $\mathbit{H}\ensuremath{\parallel}c$ is well scaled in-plane depth without showing any...
Several β-secretase inhibitors were designed based on hydroxyethylamine dipeptide isostere (HDI) structures and synthesized by a methodology using the aza-Payne rearragement O,N-acyl transfer reactions to study their structure–activity relationships. Among these pseudopeptides, effective compounds developed as first containing HDI transition state mimic with potent enzyme inhibitory activity (IC50 < 100 nM).
Peroxisome proliferator-activated receptor δ (PPARδ) is considered to be a pharmaceutical target treat metabolic diseases including atherosclerosis, but there no PPARδ agonist available for clinical use. We have previously reported the discovery of piperidinyl/piperazinyl benzothiazole derivatives as new series agonists using docking-based virtual screening methods. In present study, we found that introduction pyrrolidine group into 4-position their central piperidine rings enhances hPPARδ...