Guoyong Chen

ORCID: 0000-0003-3381-4468
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Research Areas
  • Carbohydrate Chemistry and Synthesis
  • Surfactants and Colloidal Systems
  • Liver Disease Diagnosis and Treatment
  • MRI in cancer diagnosis
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Radiomics and Machine Learning in Medical Imaging
  • Cardiovascular Function and Risk Factors
  • Analytical Chemistry and Sensors
  • Glycosylation and Glycoproteins Research
  • Cardiovascular Disease and Adiposity
  • Liquid Crystal Research Advancements
  • Molecular Sensors and Ion Detection
  • Food Chemistry and Fat Analysis
  • Epigenetics and DNA Methylation
  • Assisted Reproductive Technology and Twin Pregnancy
  • MicroRNA in disease regulation
  • RNA modifications and cancer
  • Immunotherapy and Immune Responses
  • Prenatal Screening and Diagnostics
  • Catalytic Cross-Coupling Reactions
  • Bioactive Compounds and Antitumor Agents
  • Infrared Thermography in Medicine
  • Pickering emulsions and particle stabilization
  • Acupuncture Treatment Research Studies
  • Tendon Structure and Treatment

Nanchang University
2024-2025

Guangxi Medical University
2024

West China Hospital of Sichuan University
2022-2023

Sichuan University
2022-2023

Wuhan University
2021

Wuhan Asia Heart Hospital
2021

Xiangtan University
2016-2019

Fuzhou General Hospital of Nanjing Military Command
2017

Zhengzhou People's Hospital
2009-2013

Putian University
2008

We synthesized two novel host-guest crown ether molecules [(PTFMA)(15-crown-5)ClO 4 ] ( 1 ) and [(PTFMA)(15-crown-5)PF 6 2 ). Compound transitioned from a non-centrosymmetric space group to centrosymmetric one.

10.1039/d4dt03466j article EN Dalton Transactions 2025-01-01

Low-dimensional hybrid organic–inorganic ferroelectric materials have attracted significant interest due to their outstanding optical and electrical properties. Nevertheless, many of the most extensively studied hybrids incorporate lead or tin, which raises concerns related long-term stability environmental sustainability. Here, by using quasi-spherical strategy, we designed obtained a series zero-dimensional indium metal compounds: [Me2CH2X(i-Pr)N][InBr4] (X = H, 1; F, 2; Cl, 3; Br, 4,...

10.1021/acs.inorgchem.5c00339 article EN Inorganic Chemistry 2025-03-17

Abstract Background Abdominal ectopic fat deposition and excess visceral depots in obesity may be related to cardiovascular disease (CVD) as both are involved the metabolic syndrome (MetS). The awareness of link between abdominal adiposity subclinical cardiac remodeling would help improve treatment outcome. Besides, liver fibrosis has also shown a potential relationship with dysfunction. Thus, we aimed investigate associations magnetic resonance (MR)-based hepatic shear stiffness left...

10.1186/s12933-023-01828-1 article EN cc-by Cardiovascular Diabetology 2023-04-29

Halogen engineering offers a means of enhancing the physical properties materials by fine-tuning rotational energy barrier and dipole moment, which proved to be effective in achieving switchable phase transitions optical responses materials. In this work, substituting methyl group ligand N-ethyl-1,5-diazabicyclo[3.3.0]octane (CH3CH2-3.3.0-Dabco) with halogen atoms X (Cl or Br) then contining react it FeBr3 HBr aqueous solution, we successfully synthesized three kinds organic–inorganic hybrid...

10.1021/acs.jpclett.4c01691 article EN The Journal of Physical Chemistry Letters 2024-07-16

Endometriosis (EM) interferes with the reproductive process and affects success rate of in vitro fertilization (IVF). Inflammatory cytokines are suggested to play a role infertility patients EM.In this study, we aimed investigate relationship between resistin interleukin 23 (IL-23) levels follicular fluid (FF) serum together severity endometriosis fertilization/ embryo transfer (IVF-ET) outcome.Samples from 116 infertile women were studied using enzyme-linked immunosorbent assay (ELISA). The...

10.17219/acem/41149 article EN cc-by-nc-nd Advances in Clinical and Experimental Medicine 2017-12-29

Abstract A series of alkyl β ‐ d ‐galactopyranosides were prepared by the trichloroacetimidate method with ‐galactose and alcohols different chain lengths as raw materials. Their solubility, surface tension, emulsification, foaming, wettability, thermotropic liquid crystalline properties, thermal stability investigated. Alkyl are soluble in water ethanol, solubility decreases increasing length. Decyl ‐galactopyranoside was insoluble water, but ethanol. Dissolution is an endothermic process...

10.1007/s11743-016-1865-0 article EN Journal of Surfactants and Detergents 2016-08-20

Alkyl α-D-galactopyranosides are sugar-based nonionic surfactants, and it is necessary to research their structure–property relationships since not quite clear that the change of alkyl chain length has effects on a series physicochemical properties. Here, were prepared by galactose alcohols through three steps including acetylation, coupling with in presence catalyst stannic chloride, deprotection. Furthermore, water solubility other properties investigated. (4a ∼ 4e, n = 6 10) soluble,...

10.1080/01932691.2016.1180628 article EN Journal of Dispersion Science and Technology 2016-04-29

We describe a scalable method for preparing an aminopyrazole building block using copper-catalyzed amidation with acetamide as ammonia surrogate. This procedure provides alternative to the standard nitration/reduction sequence and avoids energetic intermediates, specialized hydrogenation equipment, potentially genotoxic impurities that arise from nitro reduction. The chemistry has been successfully scaled produce >50 kg of target compound demonstrate viability this route.

10.1021/acs.oprd.1c00066 article EN Organic Process Research & Development 2021-04-06

Abstract Alkyl β‐D‐maltosides are an important class of sugar‐based nonionic surfactants and have been widely studied. Nevertheless, it is still necessary to investigate further their amphiphilic structure‐surface property relationships. In this article, we reported a series properties synthetic alkyl ( 6a – 6i , n = 6–18) including hydrophilic–lipophilic balance (HLB) number, water solubility, hygroscopicity, moisture‐retention capacity, foaming ability, surface tension, thermotropic phase...

10.1002/jsde.12281 article EN Journal of Surfactants and Detergents 2019-04-04

以葡萄糖为原料,经乙酰化、选择性脱C1位乙酰基、转化成三氯乙酰亚胺酯、与受体醇偶联和脱保护5步反应合成了11种不同碳链长度的烷基-β-D-吡喃葡萄糖苷。利用核磁共振、偏光显微镜和热失重分析法对其进行结构表征和性能测试。结果表明,当烷基-β-D-吡喃葡萄糖苷疏水烷基链长n为6—10时,均具有发泡和乳化性能,特别是正壬基β-D-吡喃葡萄糖苷(rt=9)具有更加优异的发泡和乳化性能;当烷基-β-D-吡喃葡萄糖苷疏水链的长度n/〉7时,均具有热致液晶行为,特别是正十二烷基-β-D-吡喃葡萄糖苷(n=12)和十四烷基-β-D-吡喃葡萄糖苷(n=14)能够形成更加稳定的液晶态。

10.11944/j.issn.1000-0518.2016.11.160017 article EN Chinese Journal of Applied Chemistry 2016-11-01

Inserting diffusion weighted imaging (DWI) into the time interval between post contrast and hepatobiliary phase (HBP) is saving health economic friendly. However, whether DWI would be affected before after Gd-EOB-DTPA still unknown. This study aims to validate at both low high b-values enhancement.From July 2019 November 2019, seventy-three patients who satisfied inclusion criteria were enrolled. Those scanned with multiple b-value (b-value of 0, 50, 800, 1,000, 1,200 s/mm2) using a 3.0 T...

10.21037/atm-22-962 article EN Annals of Translational Medicine 2022-03-01

Objective To study the relationship between polymorphisms of NQO1 and hepatocellular carcinoma (HCC) in Zhengzhou Guilin area.Methods The group was a hospital-based case-control which included 146 cases HCC 151 controls with nontumor seen People's Hospital Zhengzhou.The 136 123 non-tumor Medical University Hospital.NQO1 were determined by polymerase chain restriction TaqMan MGB probe.All data analyzed conditional logistic multiple factor regression analysis SPSS 18.0 statistical...

10.3760/cma.j.issn.1007-8118.2013.11.008 article EN Zhonghua gan-dan waike zazhi 2013-11-28

The aim of this study was to investigate the values computed tomography (CT) imaging technology based on image segmentation algorithm (ISA). It applied in radial shock wave therapy (RSWT) treat knee osteoarthritis (KOA), so its curative effect and rehabilitation nerve function were mainly analyzed study. 84 patients with KOA selected grouped into an ultrasonic treatment group (group A) a RSW B). All received ISA-based CT examination high-quality nursing intervention. There comparisons...

10.1155/2021/7098924 article EN Journal of Healthcare Engineering 2021-08-05

The diagnostic performance for hepatocellular carcinoma (HCC) is hampered using gadoxetic acid-enhanced magnetic resonance (MR) imaging due to the high incidence of transient severe motion in arterial phase (AP). Dynamic contrast enhanced computed tomography (CT) yield detection rate hepatic nodules AP, and combined use CT (CTAP) with MR may improve HCC. Thus, this study aimed determine whether CTAP can HCC based on various criteria.A total 169 surgically histologically confirmed (137 HCCs...

10.21037/atm-22-4968 article EN Annals of Translational Medicine 2022-11-01
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