A5101613932- Endometrial and Cervical Cancer Treatments
- Pregnancy and preeclampsia studies
- Gynecological conditions and treatments
- Cervical Cancer and HPV Research
- Ovarian cancer diagnosis and treatment
- Uterine Myomas and Treatments
- Estrogen and related hormone effects
- Genetic Syndromes and Imprinting
- Cancer-related gene regulation
- Prenatal Screening and Diagnostics
- Birth, Development, and Health
- Epigenetics and DNA Methylation
- MRI in cancer diagnosis
- Cancer Risks and Factors
- Radiomics and Machine Learning in Medical Imaging
- Endometriosis Research and Treatment
- Redox biology and oxidative stress
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Sarcoma Diagnosis and Treatment
- Sexual function and dysfunction studies
- Cancer Cells and Metastasis
- Ferroptosis and cancer prognosis
- PI3K/AKT/mTOR signaling in cancer
- Inflammatory mediators and NSAID effects
China Medical University
2025
Peking University First Hospital
2001-2023
Peking University
2001-2023
Beijing Tsinghua Chang Gung Hospital
2016-2023
Tsinghua University
2009-2023
Capital Medical University
2016
Preeclampsia is a pregnancy-specific syndrome mainly characterized by hypertensive disorder and proteinuria after gestational weeks 20. So far the etiology of preeclampsia remains unclear. We previously reported that preeclamptic placentas exhibited decreased mRNA expression hypermethylation in promoter region paternally imprinted H19 gene compared with normal placentas. has recently been identified to encode precursor miR-675, indicating possible novel functional pathway imprinting gene....
Background Preeclampsia (PE) is a pregnancy-specific syndrome manifested by on-set of hypertension and proteinuria after 20 weeks gestation. Abnormal placenta development has been generally accepted as initial cause the disorder. Recently, miR-195 was found to be down-regulated in preeclamptic placentas compared with normal pregnant ones, indicating possible association this small molecule placental pathology preeclampsia. By far function remains unknown. Methodology/Principal Findings...
The pregnancy-specific disorder preeclampsia is a major cause of maternal mortality and morbidity. Activin A has been suggested as potential biomarker the disease, but whether it plays role in pathology or just manifestation disease not fully understood. objective study was to examine roles on placental trophoblast cells under pathological conditions preeclampsia. Placental plasma productions healthy pregnant women preeclamptic patients were compared by using clinical samples obtained from...
This study aimed to assess the predictive value of radiomic analysis derived from primary lesions and ipsilateral axillary suspicious lymph nodes (SLN) on dynamic contrast-enhanced MRI (DCE-MRI) for evaluating response neoadjuvant therapy (NAT) in early high-risk advanced breast cancer (BC) patients. A retrospective was conducted 222 BC patients (192 Center I 30 II) who underwent NAT. Radiomic features were extracted lesion (intra- peritumoral regions) SLN develop signatures (RS-primary,...
Objective This study aimed to detect the expression of Akt, mTOR, and Pax-2 in differing endometrial tissue/cells, together with assessment such molecular markers for improving accuracy within cytology screening cancer (EC). Methods Overall, 92 hysteroscopy cases were included. cohort comprised 32 carcinoma patients, 30 benign lesion normal endometrium. Endometrial cells collected before hysteroscopy, immunohistochemical (IHC) immunocytochemical (ICC) detection Pax-2. Expression levels...
Liquid-based cytology (LBC) offers an alternative method to biopsy in screening endometrial cancer. Cell block (CB), prepared by collecting residual cytological specimen, represents a novel supplement the diagnosis of cytology. This study aimed compare specimen adequacy and diagnostic accuracy LBC CB lesions.A total 198 women with high risks carcinoma (EC) from May 2014 April 2015 were enrolled this study. The specimens collected sampler (SAP-1) followed histopathologic evaluation dilatation...
The aim of this study was to investigate the diagnostic accuracy liquid-based endometrial cytology in postmenopausal women, comparison with histology. There were 790 women scheduled for hysteroscopy enrolled study. After providing informed consent, all patients proceeded sequentially through cytology, hysteroscopy, and then dilatation curettage (D&C). Cytology sampling performed by brushing uterus cavity using SAP-1 sample prepared smear SurePath technology. slides stained Papanicolaou...
The Wnt signaling pathway plays an essential role in tumor invasion and migration. DKK1 functions as important inhibitor of the represents a promising target for cancer therapy. aim present study was to determine endometrial carcinoma (EC) cell migration using RNA interference (RNAi) technology. Ishikawa EC cells were transfected at high efficiency with specific siRNA. RT‑PCR western blot analysis used mRNA protein levels DKK1, β‑catenin metalloproteinase 14 (MMP14) siRNA‑treated ‑untreated...
The current study is designed to evaluate certain immunocytochemical (ICC) biomarkers gain a better cytodiagnosis. For this purpose, 85 patients from March 2016 2019 who planned get hysteroscopy assay were recruited. Cytological sampling was conducted by scratching the uterus cavity using SAP-1, and samples processed as liquid-based smears, SurePath technology. 36 diagnosed with EC or atypical endometrial hyperplasia recruited in study. 33 cases EC, 3 hyperplasia, allocated precancerous...
Laparoscopic-assisted radical vaginal hysterectomy (LARVH) and abdominal (ARH) are commonly used for cervical cancer treatment. However, the clinical application of LARVH versus ARH in treating remains controversial.To investigate efficacy via comparing several inductors by pooling related studies.Eligible articles from PubMed, Embase, Cochrane library were screened using established search terms. Consecutive variables pooled weighted mean difference (WMD) 95% confidence interval (CI)....
Objective To evaluate the accuracy of endometrial cytology test (ECT) for diagnosis cancer or precancerous lesions and then discuss value ECT as a screening tool cancer.Secondly,to investigate related characteristics independent risk factors epidemiology carcinomas atypical hyperplasia to advise proper crowd monitoring. Methods Totally 1717 preoperative questionnaires on hysteroscopy+ dilation& curettage,histopathology cytological tests in Peking University First Hospital,People's...
You have accessJournal of UrologyDiscussed Poster, Tuesday, May 24, 2005, 1:00 - 5:00 pm1 Apr 20051251: Effect Alprostadil Cream on Cerebral Responses Using Functional Magnetic Resonance Imaging in Women with Sexual Arousal Disorder Qinping Liao, Miao Zhang, Sheng Xie, Joseph Mo, and Ming Q. Lu LiaoQinping Liao More articles by this author , ZhangMiao Zhang XieSheng Xie MoJoseph Mo LuMing View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)35396-5AboutPDF ToolsAdd to...