47 Background: Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide. Early detection and accurate diagnosis are essential for improving survival rates optimizing therapeutic strategies. Recently, artificial intelligence (AI) technologies, such as machine learning algorithms, convolutional neural networks (CNNs), computer-assisted diagnostic (CAD) systems, have significantly enhanced traditional tools like colonoscopy histopathology. This systematic review...

Canine heartworm, Dirofilaria immitis, is a nematode parasite that infects dogs by way of mosquito bite. Rarely, humans play accidental hosts to this and are not suitable environment for the live. As dies in pulmonary vessels it embolizes causing infarction eventual nodule formation lungs. In right clinical context, can be considered malignant prompting invasive tissue sampling. We describe case 48-year-old man who was found have multiple asymptomatic scattered nodules during imaging workup...

The Kytococcus genus formerly belonged to Micrococcus. first report of a schroeteri infection was in 2002 patient diagnosed with endocarditis. We case central line associated bacteremia underlying Hairy Cell Leukemia. is an emerging the neutropenic population and patients implanted artificial tissue. It thought be commensal bacterium skin; however, attempts culture bacteria remain unsuccessful. There have been total 5 cases (including ours) K. hematologic malignancies neutropenia only 18...

Thrombotic thrombocytopenic purpura (TTP) is caused by the deficiency of ADAMTS13, a von Willebrand factor cleaving protease, which results in thrombotic microangiopathy. It characterized microangiopathic hemolytic anemia, thrombocytopenia, and microvascular thrombosis leading to organ damage. has an extremely high mortality rate if left untreated, making early diagnosis treatment utmost importance. We report case TTP that developed after vaccination with Ad26.COV2.S COVID vaccine. present...

SAPHO syndrome is a rare clinical entity composed of synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO). We describe case masquerading as metastatic breast cancer in patient with localized who presented cord compression. There was no pathologic evidence cancer; however, bone scan indicated osseous involvement. After multidisciplinary review images additional findings pustulosis diagnosis made.

Retroperitoneal fibrosis (RPF) is a rare condition characterized by fibroinflammatory tissue infiltrating and compressing retroperitoneal structures. While mostly idiopathic (idiopathic or IRF), RPF frequently associated with certain drugs, infections, malignancies. It thought to be immune-mediated because of response steroids commonly seen other autoimmune diseases, especially IgG4-related disease (IgG4-RD). IRF also part the chronic aortitis syndromes presence aortic aneurysms another...

Sjogren syndrome is an autoimmune disorder that leads to dryness in the eyes and mouth. Nodular pulmonary amyloidosis a localized amyloid deposition pathology commonly seen with monoclonal lymphoproliferative disorders. We present patient who came dyspnea was found have nodular on biopsy. Commonly associated pathologies were ruled out further workup, syndrome. This case demonstrates as rare presentation of setting relatively well-controlled symptoms. Detection should prompt evaluation...

Learning point for cliniciansPoroid hidradenoma is a rare but important differential diagnosis slow-growing breast mass which can be misinterpreted malignant process as both the clinical well radiological picture deceptively similar to cancerous lesion.

TO THE EDITOR: We would like to report 2 cases of multiple myeloma (MM) complicated by myelomatous pleural effusions (MPE). MM is a malignant transformation and proliferation single clone plasma cells, which typically infiltrates the bone marrow produces monoclonal immunoglobulins (Ig). In United States, annual incidence 4-5 per 100,000. Myeloma accounts for 1% all cancers slightly over 10% hematologic malignancies [1]. Recent advancements in treatment have resulted significantly improved...

Muir-Torre syndrome (MTS) is an autosomal dominant condition characterized by dermatological tumors along with visceral malignancies. The manifestations include recurrent sebaceous adenomas and keratoacanthomas. commonly seen malignancies are colorectal, gynecological, urological. It a variant of hereditary non-polyposis colorectal carcinoma (HNPCC). underlying genetic mechanism germline mutations in the DNA mismatch repair (MMR) genes leading to microsatellite instability (MSI), conferring...

Introduction: An abdominal aortic aneurysm (AAA) is defined when infra-renal diameter at least 3.0 cm. The United States Preventive Services Task Force recommended in 2005 that all men between the ages of 65 to 75 years who have ever smoked should be screened once for AAA by ultrasonography. However, clinical impact these recommendations are unknown. Methods: We queried Healthcare Cost and Utilization Project’s Nationwide Inpatient Sample (NIS) data rupture using ICD9 codes 441.4 441.3...

Introduction: Paclitaxel is an antineoplastic chemotherapeutic agent used to treat various malignancies. The mechanism of action involves interference with microtubules during cell division. Various adverse effects exist, but bowel perforation a rare complication. cause thought be related chemotherapy-induced neutropenia and necrosis as direct effect the medication. We present case soon after administration paclitaxel. Case Description/Methods: A 43-year-old woman family medical history...

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Introduction: Somatostatinoma is a rare neuroendocrine tumor often associated with neurofibromatosis type 1, Von Hippel Lindau syndrome, and tuberous sclerosis. The incidence of somatostatinoma estimated to be 1 in 40 million. Somatostatinomas have an insidious growth, as result, it presents later stages malignant disease. presenting “somatostatinoma syndrome,” which consists diarrhea, diabetes, gallstones, uncommon. Case Description/Methods: We present the case 24-year-old female who newly...