A5078228283- Cancer-related cognitive impairment studies
- Dementia and Cognitive Impairment Research
- Glioma Diagnosis and Treatment
- Breast Cancer Treatment Studies
- Brain Metastases and Treatment
- Advanced Breast Cancer Therapies
- Health, Environment, Cognitive Aging
- Nutritional Studies and Diet
- Frailty in Older Adults
- BRCA gene mutations in cancer
- Cognitive Functions and Memory
- Estrogen and related hormone effects
- Neurobiology of Language and Bilingualism
- Educational and Psychological Assessments
The Netherlands Cancer Institute
2020-2023
Dutch Cancer Society
2021
University of Amsterdam
2020
Oncode Institute
2020
Amsterdam Neuroscience
2017-2019
Amsterdam University Medical Centers
2019
Vrije Universiteit Amsterdam
2019
The cognitive-functional composite (CFC) was designed to improve the measurement of clinically relevant changes in predementia and early dementia stages. We have previously demonstrated its good test-retest reliability feasibility use. current study aimed evaluate several quality aspects CFC, including construct validity, clinical relevance, suitability for target population. Baseline data Capturing Changes Cognition used: an international, prospective cohort participants with subjective...
Abstract Background Cognitive effects of tamoxifen have been described. We augment data from a previous short-term (ST) follow-up study with long-term (LT) to evaluate ST and LT cognitive followed by exemestane in breast cancer patients. Methods Patients the Tamoxifen Exemestane Adjuvant Multinational trial received 5 years (exemestane group, n = 114) or 2.5 (sequential 92). Neuropsychological performance was assessed pre-endocrine therapy, after 1 year (ST follow-up) at (LT follow-up). A...
To examine the effect of a premenopausal risk-reducing salpingo-oophorectomy (RRSO) in women at increased risk ovarian cancer on objective and subjective cognition least 10 years after RRSO.A cross-sectional study with prospective follow-up, nested nationwide cohort.Multicentre Netherlands.641 (66% BRCA1/2 pathogenic variant carriers) who underwent either RRSO ≤ age 45 (n = 436) or postmenopausal ≥ 54 205). All participants were older than 55 recruitment.Participants completed an online...
To improve the detection of changes in Alzheimer's disease (AD), we designed cognitive-functional composite (CFC). As a first validation step, investigated its test-retest reliability and feasibility use.We performed study with 2-3 weeks between assessments, including patients mild cognitive impairment (MCI) or AD dementia cognitively healthy participants. We calculated intraclass correlation coefficients (ICCs) type absolute agreement for all CFC measures compared baseline retest scores...
Objective: Since computerized cognitive test performance may be influenced by computer experience, correction for this measure might needed. This study examined how to correct experience examining its influence on online and traditional tests. Method: 248 healthy adults completed an neuropsychological battery 70 equivalents of the Computer was assessed a performance-based self-report measure. Regression analyses were applied examine their Results: After demographics, associated with...
There is a need to better identify impaired cognitive processes increase our understanding of dysfunction caused by cancer and treatment improve interventions. The Trail Making Test frequently used for evaluating information-processing speed (part A) executive function B), but interpretation its outcomes challenging because performance depends on many processes. To disentangle processes, we collected high-resolution data from 192 non-central nervous system patients who received systemic...
Introduction Despite an increasing need for new Rey Auditory Verbal Learning Test (RAVLT)-based word lists in computerized testing, no criteria or standardized procedures exist its development. To lay a foundation future development of and alternate RAVLT(-based) lists, we present cross-lingual criteria, developed using the evaluated performance on online assessment.Method Based psycholinguistic literature, identified relevant selection criteria. validate two American-English one Dutch list,...